Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Natalia L. Peeck"'
Autor:
Chunlei Jiao, Natalia L. Peeck, Jiaqi Yu, Mohammad Ghaem Maghami, Sarah Kono, Daphne Collias, Sandra L. Martinez Diaz, Rachael Larose, Chase L. Beisel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Many CRISPR-Cas immune systems generate guide (g)RNAs using trans-activating CRISPR RNAs (tracrRNAs). Recent work revealed that Cas9 tracrRNAs could be reprogrammed to convert any RNA-of-interest into a gRNA, linking the RNA’s presence to
Externí odkaz:
https://doaj.org/article/fae1f70b488348a591a8db8b7fd3dca3
Autor:
Chunlei Jiao, Sahil Sharma, Lars Barquist, Yanying Yu, Oliver Kurzai, Christoph Schoen, Gaurav Dugar, Natalia L. Peeck, Franziska Wimmer, Cynthia M. Sharma, Thorsten Bischler, Chase L. Beisel
Publikováno v:
Science (New York, N.y.)
Cellular RNAs guide CRISPR-Cas9 The Cas9 nuclease widely used for genome editing is derived from natural bacterial defense systems that protect against invading viruses. Cas9 is directed by RNA guides to cut matching viral DNA. Jiao et al. discovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0479d0730260a491d7b532522657ec7b
https://doi.org/10.1126/science.abe7106
https://doi.org/10.1126/science.abe7106