Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Natalia L Klyachko"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Last decade, extracellular vesicles (EVs) attracted a lot of attention as potent versatile drug delivery vehicles. We reported earlier the development of EV-based delivery systems for therapeutic proteins and small molecule chemotherapeutics
Externí odkaz:
https://doaj.org/article/f7622b59ef5e4a1c84f9e241843437dc
Autor:
Matthew J Haney, Yuling Zhao, Emily B Harrison, Vivek Mahajan, Shaheen Ahmed, Zhijian He, Poornima Suresh, Shawn D Hingtgen, Natalia L Klyachko, R Lee Mosley, Howard E Gendelman, Alexander V Kabanov, Elena V Batrakova
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61852 (2013)
The ability to precisely upregulate genes in inflamed brain holds great therapeutic promise. Here we report a novel class of vectors, genetically modified macrophages that carry reporter and therapeutic genes to neural cells. Systemic administration
Externí odkaz:
https://doaj.org/article/078f3c2104194a308a193b155ebaecb6
Publikováno v:
Nanomaterials, Vol 14, Iss 5, p 411 (2024)
The modern global trend toward sustainable processes that meet the requirements of “green chemistry” provides new opportunities for the broad application of highly active, selective, and specific enzymatic reactions. However, the effective applic
Externí odkaz:
https://doaj.org/article/932210e7487c4306a78cdd76250a0507
Autor:
Azizbek D. Usvaliev, Natalia G. Belogurova, Konstantin V. Pokholok, Alexander V. Finko, Andrey N. Prusov, Dmitry Yu. Golovin, Konstantin A. Miroshnikov, Yuri I. Golovin, Natalia L. Klyachko
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1871 (2023)
The spreading of microbial pathogens with more and more resistance to traditional low-molecular antibiotic agents demands new approaches to antibacterial therapy. The employment of bacteriophage enzymes capable of breaking bacterial cell walls has at
Externí odkaz:
https://doaj.org/article/59894295d0c442fcb8c64157fb2c8a32
Autor:
Alexander N. Vaneev, Roman V. Timoshenko, Petr V. Gorelkin, Natalia L. Klyachko, Alexander S. Erofeev
Publikováno v:
Nanomaterials, Vol 13, Iss 9, p 1573 (2023)
Recently, nanopore technology has emerged as a promising technique for the rapid, sensitive, and selective detection of various analytes. In particular, the use of nanopores for the detection of copper ions has attracted considerable attention due to
Externí odkaz:
https://doaj.org/article/ad46b357a261448584551be22214fcf3
Autor:
Sofia A. Shilova, Maria G. Khrenova, Ilya O. Matyuta, Alena Y. Nikolaeva, Tatiana V. Rakitina, Natalia L. Klyachko, Mikhail E. Minyaev, Konstantin M. Boyko, Vladimir O. Popov, Ekaterina Yu. Bezsudnova
Publikováno v:
Molecules, Vol 28, Iss 5, p 2109 (2023)
Pyridoxal-5′-phosphate (PLP)-dependent transaminases are highly efficient biocatalysts for stereoselective amination. D-amino acid transaminases can catalyze stereoselective transamination producing optically pure D-amino acids. The knowledge of su
Externí odkaz:
https://doaj.org/article/cf5db3b6aea04fe59391ae10650babe0
Autor:
Alexander N. Vaneev, Roman V. Timoshenko, Petr V. Gorelkin, Natalia L. Klyachko, Yuri E. Korchev, Alexander S. Erofeev
Publikováno v:
Nanomaterials, Vol 12, Iss 21, p 3736 (2022)
Electrochemical nano- and microsensors have been a useful tool for measuring different analytes because of their small size, sensitivity, and favorable electrochemical properties. Using such sensors, it is possible to study physiological mechanisms a
Externí odkaz:
https://doaj.org/article/b73209685b7046a8a092c9fc201aa35d
Autor:
Svetlana Yu. Maklakova, Anton V. Lopukhov, Alexandr D. Khudyakov, Sergey V. Kovalev, Maria P. Mazhuga, Olga E. Chepikova, Andrey A. Zamyatnin, Alexander G. Majouga, Natalia L. Klyachko, Elena K. Beloglazkina
Publikováno v:
RSC Medicinal Chemistry. 14:56-64
Atorvastatin conjugates targeting the galactose-specific hepatic asialoglycoprotein receptor with improved stability are reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d97596c09ca6223ee6a8cecdd3856c24
https://doi.org/10.1039/d2md00119e
https://doi.org/10.1039/d2md00119e
Autor:
Sofia A. Zakharenkova, Marina I. Lebedeva, Alexandra N. Lebedeva, Irina A. Doroshenko, Ksenya Yu Vlasova, Anastasiya A. Bartoshevich, Vladimir M. Senyavin, Sergey S. Abramchuk, George G. Krivtsov, Alexander A. Ezhov, Tatyana A. Podrugina, Natalia L. Klyachko, Mikhail K. Beklemishev
Publikováno v:
Molecules, Vol 26, Iss 24, p 7426 (2021)
Imaging-guided delivery is developed for hydrophobic drugs, and to a much lesser extent, hydrophilic ones. In this work we have designed a novel strategy for real-time monitoring of hydrophilic drug delivery. Traditionally, the drug and the dye are c
Externí odkaz:
https://doaj.org/article/fb149f8761c444b195dbb937f0a59d4a
Autor:
Ivan A. Burmistrov, Maxim M. Veselov, Alexander V. Mikheev, Tatiana N. Borodina, Tatiana V. Bukreeva, Michael A. Chuev, Sergey S. Starchikov, Igor S. Lyubutin, Vladimir V. Artemov, Dmitry N. Khmelenin, Natalia L. Klyachko, Daria B. Trushina
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 65 (2021)
Nanosystems for targeted delivery and remote-controlled release of therapeutic agents has become a top priority in pharmaceutical science and drug development in recent decades. Application of a low frequency magnetic field (LFMF) as an external stim
Externí odkaz:
https://doaj.org/article/10e2128294c54371ac6db3082c83559c