Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Natalia Komarova"'
Autor:
Alexander Kuznetsov, Mariia Andrianova, Dmitriy Ryazantsev, Andrey Sheshil, Vitaliy Grudtsov, Valerii Vechorko, Natalia Komarova
Publikováno v:
Sensors International, Vol 6, Iss , Pp 100302- (2025)
Study of enzyme-substrate interactions is a task of great practical and scientific importance. This paper describes the application of ion-sensitive field effect transistors in quasi-equilibrium state for examination of enzymatic reactions. A reactio
Externí odkaz:
https://doaj.org/article/0300cbdeb3e74044b6bf0d086e0f9c0b
Autor:
Alexander Kuznetsov, Andrey Sheshil, Eugene Smolin, Vitaliy Grudtsov, Dmitriy Ryazantsev, Mark Shustinskiy, Tatiana Tikhonova, Irakli Kitiashvili, Valerii Vechorko, Natalia Komarova
Publikováno v:
Sensors, Vol 24, Iss 11, p 3681 (2024)
Fabry disease is a lysosomal storage disorder caused by a significant decrease in the activity or absence of the enzyme α-galactosidase A. The diagnostics of Fabry disease during newborn screening are reasonable, due to the availability of enzyme re
Externí odkaz:
https://doaj.org/article/0d33e8769d604137a39d06f2f2acb96a
Autor:
Dmitriy Ryazantsev, Mark Shustinskiy, Andrey Sheshil, Alexey Titov, Vitaliy Grudtsov, Valerii Vechorko, Irakli Kitiashvili, Kirill Puchnin, Alexander Kuznetsov, Natalia Komarova
Publikováno v:
Sensors, Vol 24, Iss 10, p 3008 (2024)
Biosensors based on ion-sensitive field effect transistors (ISFETs) combined with aptamers offer a promising and convenient solution for point-of-care testing applications due to the ability for fast and label-free detection of a wide range of biomar
Externí odkaz:
https://doaj.org/article/7471559951634eeb8d3727893c10051e
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 5, p e1010039 (2022)
Feedback mechanisms within cell lineages are thought to be important for maintaining tissue homeostasis. Mathematical models that assume well-mixed cell populations, together with experimental data, have suggested that negative feedback from differen
Externí odkaz:
https://doaj.org/article/35617fe724d5424b9b22d677d13706e3
Publikováno v:
Biology and Life Sciences Forum, Vol 20, Iss 1, p 26 (2022)
Aptamers are nucleic acid ligands which exhibit specific binding to a desired target. Oligonucleotides are limited in their ability to form hydrophobic interactions. The affinity of aptamers can be improved with the introduction of hydrophobic modifi
Externí odkaz:
https://doaj.org/article/18ea1da3f5424152a0e7b13f2e29dcb1
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1085 (2022)
The detection of cardiac biomarkers is used for diagnostics, prognostics, and the risk assessment of cardiovascular diseases. The analysis of cardiac biomarkers is routinely performed with high-sensitivity immunological assays. Aptamers offer an attr
Externí odkaz:
https://doaj.org/article/c618847995694a3f814626fde6e4a9a3
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8774 (2020)
Aptamers are nucleic acid ligands that bind specifically to a target of interest. Aptamers have gained in popularity due to their high potential for different applications in analysis, diagnostics, and therapeutics. The procedure called systematic ev
Externí odkaz:
https://doaj.org/article/bdeeab1973d145fcae715fbc48c22cbe
Autor:
Natalia Komarova, Alexander Kuznetsov
Publikováno v:
Molecules, Vol 24, Iss 19, p 3598 (2019)
Aptamers are small oligonucleotides that are capable of binding specifically to a target, with impressive potential for analysis, diagnostics, and therapeutics applications. Aptamers are isolated from large nucleic acid combinatorial libraries using
Externí odkaz:
https://doaj.org/article/023aef7f90ac4d09aaeed5d97e292cdd
Publikováno v:
Molecules, Vol 23, Iss 12, p 3159 (2018)
Furaneol is an aroma compound which occurs naturally in foods and is used as an artificial flavor. Detection of furaneol is required in food science and food processing industry. Capture- Systematic Evolution of Ligands by EXponential enrichment (SEL
Externí odkaz:
https://doaj.org/article/1e4853d391774bad8e9cb7814ebe03df
Autor:
Mariia Andrianova, Natalia Komarova, Vitaliy Grudtsov, Evgeniy Kuznetsov, Alexander Kuznetsov
Publikováno v:
Sensors, Vol 18, Iss 1, p 49 (2017)
The electrochemical detection of interactions between aptamers and low-molecular-weight targets often lacks sensitivity. Signal amplification improves the detection of the aptamer-analyte complex; Bsm DNA polymerase was used to amplify the signal fro
Externí odkaz:
https://doaj.org/article/08caaeb216304d2dae5de825843dbf73