Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Natalia Kleschevnikov"'
Autor:
Shanshan Wang, Joseph S. Leem, Sonia Podvin, Vivian Hook, Natalia Kleschevnikov, Paul Savchenko, Mehul Dhanani, Kimberly Zhou, Isabella C. Kelly, Tong Zhang, Atsushi Miyanohara, Phuong Nguyen, Alexander Kleschevnikov, Steve L. Wagner, John Q. Trojanowski, David M. Roth, Hemal H. Patel, Piyush M. Patel, Brian P. Head
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 434-450 (2021)
Alzheimer’s disease (AD) is the most common form of neurodegeneration and cognitive dysfunction in the elderly. Identifying molecular signals that mitigate and reverse neurodegeneration in AD may be exploited therapeutically. Transgenic AD mice (PS
Externí odkaz:
https://doaj.org/article/9a008a9a994349fab892e7d7e193a9c9
Autor:
Isabella C. Kelly, Mehul Dhanani, John Q. Trojanowski, Kimberly Zhou, Sonia Podvin, Steve L. Wagner, Atsushi Miyanohara, Shanshan Wang, Piyush M. Patel, Tong Zhang, Vivian Hook, Alexander M. Kleschevnikov, Phuong Nguyen, Joseph Leem, Natalia Kleschevnikov, Brian P. Head, David M. Roth, Hemal H. Patel, Paul Savchenko
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 434-450 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 434-450 (2021)
Alzheimer’s disease (AD) is the most common form of neurodegeneration and cognitive dysfunction in the elderly. Identifying molecular signals that mitigate and reverse neurodegeneration in AD may be exploited therapeutically. Transgenic AD mice (PS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecde459cbf8b7e4efc353012ef591897
https://doi.org/10.1016/j.omtm.2021.03.021
https://doi.org/10.1016/j.omtm.2021.03.021
Autor:
Shanshan Wang, Joseph Leem, Sonia Podvin, Vivian Hook, Natalia Kleschevnikov, Paul Savchenko, Mehul Dhanani, Kimberly Zhou, Isabella Kelly, Tong Zhang, Atsushi Miyanohara, Alexander Kleschevnikov, Steve Wagner, John Trojanowski, David Roth, Hemal Patel, Piyush Patel, Brian Head
Background: AD presents with severe neurodegeneration which leads to cognitive deficits and dementia. While many previous approaches focused on targeting amyloid and/or tau, we identified a novel molecular and cellular target that attenuates neurodeg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38412678667f748d1ff2340cd76256b1
https://doi.org/10.21203/rs.3.rs-79305/v1
https://doi.org/10.21203/rs.3.rs-79305/v1
Autor:
John Q. Trojanowski, Brian P. Head, Atsushi Miyanohara, Mehul Dhanani, Tong Zhang, Paul Savchenko, Isabella C. Kelly, Sonia Podvin, Steve L. Wagner, Vivian Hook, Alexander M. Kleschevnikov, Natalia Kleschevnikov, Shanshan Wang, Kimberly Zhou, David M. Roth, Joseph Leem, Hemal H. Patel, Piyush M. Patel
AD presents with severe neurodegeneration which leads to cognitive deficits and dementia. Identifying the molecular signals that attenuate neurodegeneration in AD may be exploited as therapeutic targets. This study revealed that transgenic AD mice (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd4e440291b2ab8dce87aa0e8bc2f05
https://doi.org/10.1101/2020.07.24.220129
https://doi.org/10.1101/2020.07.24.220129