Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Natalia Gonzalez-Paz"'
Autor:
Arif H. Kamal, Sumithra J. Mandrekar, Natalia Gonzalez-Paz, Patricia T. Greipp, Eric W. Schaefer, Philip R. Greipp, Prashant Kapoor, Shaji Kumar
Publikováno v:
Mayo Clinic Proceedings. 85:905-912
OBJECTIVE To determine clinical features, natural history, and outcome of a well-defined cohort of 25 consecutive patients with idiopathic systemic capillary leak syndrome (SCLS) evaluated at a tertiary care center. PATIENTS AND METHODS Records of pa
Autor:
Ruifang Xu, C. Aguilera, Syed M. Jalal, J.M. Hernández-Rivas, Enrique M. Ocio, Angela Dispenzieri, Morie A. Gertz, Roelandt F.J. Schop, P R Greipp, Norma C. Gutiérrez, Moro Mj, Martha Q. Lacy, R. García-Sanz, B. Gonzalez, S Van Wier, J M Hernández, R Fonseca, Natalia Gonzalez-Paz, J F San Miguel
Publikováno v:
British Journal of Haematology. 136:80-86
Fluorescence in situ hybridisation (FISH) is an effective technique for the cytogenetic analysis of Waldenstrom macroglobulinemia (WM), but the potential impact of molecular cytogenetics on disease evolution and as a prognostic marker is still unknow
Autor:
Morie A. Gertz, Natalia Gonzalez Paz, Roshini S. Abraham, Angela Dispenzieri, Tammy Price-Troska, Diane E. Grill, Rafael Fonseca, Karla V. Ballman, Michelle K. Manske
Publikováno v:
Blood. 105:794-803
Immunoglobulin light chain amyloidosis (AL) is characterized by a clonal expansion of plasma cells within the bone marrow. Gene expression analysis was used to identify a unique molecular profile for AL using enriched plasma cells (CD138+) from the b
Autor:
Doris N. Savoy, Natalia Gonzalez-Paz, Rafael Fonseca, Ellen A. Weiss, Martin E. Fernandez-Zapico, Daniel D. Billadeau, Raul Urrutia, Suresh T. Chari, Julian R. Molina, Thomas C. Smyrk
Publikováno v:
Cancer Cell. 7(1):39-49
Herein, we show that the hematopoietic-specific GEF VAV1 is ectopically expressed in primary pancreatic adenocarcinomas due to demethylation of the gene promoter. Interestingly, VAV1-positive tumors had a worse survival rate compared to VAV1-negative
The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
Autor:
Morie A. Gertz, Martin M. Oken, Jerry M. Winkler, Gordon W. Dewald, Rafael Fonseca, Robert A. Kyle, Emily A. Blood, Natalia Gonzalez-Paz, Carina S. Debes-Marun, Philip R. Greipp, Martha Q. Lacy, Sandra C. Bryant, Angela Dispenzieri, Rafael Santana-Davila, Elisa B. Picken
Publikováno v:
Blood. 102:2562-2567
Aneuploid is ubiquitous in multiple myeloma (MM), and 4 cytogenetic subcategories are recognized: hypodiploid (associated with a shorter survival), pseudodiploid, hyperdiploid, and near-tetraploid MM. The hypodiploid, pseudodiploid, and near-tetraplo
Autor:
B Van Ness, Kim Henderson, Tammy Price-Troska, Wee Joo Chng, R Fonseca, Natalia Gonzalez-Paz, S Van Wier, Susanna Jacobus, S V Rajkumar, Patricia T. Greipp, Emily A. Blood, Martin M. Oken
Publikováno v:
Leukemia. 21:582-584
Autor:
Natalia Gonzalez-Paz, Marta Chesi, Tae-Hoon Chung, George Mulligan, Siok Bian Ng, T Troska-Price, Wee Joo Chng, P L Bergsagel, Gaofeng Huang, R Fonseca
Publikováno v:
Leukemia
Events mediating transformation from the pre-malignant monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) are unknown. We analyzed a gene expression datasets generated on the Affymetrix U133 platform from 22 MGUS and 1
Autor:
Patricia T. Greipp, Kim Henderson, Susanna Jacobus, Wee Joo Chng, B Van Ness, R Fonseca, Natalia Gonzalez-Paz, Robert A. Kyle, Tammy Price-Troska, S Van Wier, S V Rajkumar, Martin M. Oken
Primary genetic abnormalities in myeloma (MM) such as trisomies of chromosomes 3, 5, 7, 9, 11, 15, 19 and 21 associated with hyperdiploid MM and translocations involving the immunoglobulin heavy chain (IgH) locus on chromosome 14q32 and three main re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90e8f362488794436d9e21ebd40e519
https://europepmc.org/articles/PMC3864109/
https://europepmc.org/articles/PMC3864109/
Autor:
Rebecca F. McClure, Martha Q. Lacy, Morie A. Gertz, Wee Joo Chng, Paul J. Kurtin, Emily A. Blood, Kimberly J. Henderson, Angela Dispenzieri, Rafael Fonseca, C. David James, Martin M. Oken, Gregory J. Ahmann, Natalia Gonzalez-Paz, Philip R. Greipp, Brian G Van Ness
Publikováno v:
Blood. 109(3)
The biological and clinical implications of p16 gene methylation in multiple myeloma (MM) are still unclear despite previous studies. In this comprehensive study, using methylation-specific PCR (MS-PCR), we show that p16 methylation is relatively com
Autor:
Angela Dispenzieri, Robert A. Kyle, Rafael Santana-Davila, Elisa B. Picken, Sandra C. Bryant, S V Rajkumar, C S Debes-Marun, Natalia Gonzalez-Paz, Martha Q. Lacy, T. E. Witzig, Jerry M. Winkler, John A. Lust, Rafael Fonseca, Morie A. Gertz, P R Greipp, Gordon W. Dewald
Publikováno v:
Leukemia. 17(2)
The nonrandom recurrent nature of chromosome abnormalities in myeloma suggests a role for them in disease pathogenesis. We performed a careful cytogenetic analysis of patients with abnormal karyotypes (n = 254), to discern patterns of association, se