Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Natalia Goldin"'
Publikováno v:
Journal of Bioenergetics and Biomembranes. 39:51-57
Jasmonates are plant stress hormones that induce suppression of proliferation and death in cancer cells, while being selectively inactive towards non-transformed cells. Jasmonates can overcome apoptotic blocks and exert cytotoxic effects on drug-resi
Autor:
Natalia Goldin, Ronit Rotem, Israel Zan-Bar, Eliezer Flescher, Orit Fingrut, Dorit Reischer, Irit Altboum
Publikováno v:
British Journal of Pharmacology. 146:800-808
Mutations in p53, a tumor suppressor gene, occur in more than half of human cancers. Therefore, we tested the hypothesis that jasmonates (novel anticancer agents) can induce death in mutated p53-expressing cells. Two clones of B-lymphoma cells were s
Autor:
Tsafrir Bravman, Ariel G. Notcovich, Adrian Israelson, Z. Zaslavsky, Eliezer Flescher, Vered Bronner, Natalia Goldin, Laetitia Arzoine, Alina Heyfets, Varda Shoshan-Barmatz
Publikováno v:
Oncogene. 27(34)
Cellular bio-energetic metabolism and mitochondria are recognized as potential targets for anticancer agents, due to the numerous relevant peculiarities cancer cells exhibit. Jasmonates are anticancer agents that interact directly with mitochondria.
Autor:
Orit, Fingrut, Dorit, Reischer, Ronit, Rotem, Natalia, Goldin, Irit, Altboum, Israel, Zan-Bar, Eliezer, Flescher
Publikováno v:
British journal of pharmacology. 146(6)
Mutations in p53, a tumor suppressor gene, occur in more than half of human cancers. Therefore, we tested the hypothesis that jasmonates (novel anticancer agents) can induce death in mutated p53-expressing cells. Two clones of B-lymphoma cells were s