Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Natalia Fernández-Borges"'
Autor:
Alba Marín-Moreno, Sylvie L. Benestad, Tomas Barrio, Laura Pirisinu, Juan Carlos Espinosa, Linh Tran, Alvina Huor, Michele Angelo Di Bari, Hasier Eraña, Ben C. Maddison, Claudia D’Agostino, Natalia Fernández-Borges, Sara Canoyra, Nuria Jerez-Garrido, Joaquín Castilla, John Spiropoulos, Keith Bishop, Kevin C. Gough, Romolo Nonno, Jorn Våge, Olivier Andréoletti, Juan María Torres
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem of the animal. Two different western blotting tests were conducted independently
Externí odkaz:
https://doaj.org/article/51a3b8f500ba47a290cef12832a53307
Autor:
Alba Marín-Moreno, Juan Carlos Espinosa, Patricia Aguilar-Calvo, Natalia Fernández-Borges, José Luis Pitarch, Lorenzo González, Juan María Torres
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract E/D163 polymorphism of dog prion protein (PrP) has been recently proposed as the variant responsible for canid prion resistance. To further investigate the protective role of this variant against prion replication, the transgenic mouse model
Externí odkaz:
https://doaj.org/article/dd52988c19cf4e058e4786fdf4f8fbf6
Autor:
Alba Marín-Moreno, Patricia Aguilar-Calvo, Juan Carlos Espinosa, María Zamora-Ceballos, José Luis Pitarch, Lorenzo González, Natalia Fernández-Borges, Leonor Orge, Olivier Andréoletti, Romolo Nonno, Juan María Torres
Publikováno v:
Veterinary Research, Vol 52, Iss 1, Pp 1-15 (2021)
Abstract The diversity of goat scrapie strains in Europe has recently been studied using bioassays in a wide collection of rodent models, resulting in the classification of classical scrapie into four different categories. However, the sole use of th
Externí odkaz:
https://doaj.org/article/e64c541f75a7499a9890e417ae1cf878
Autor:
Alba Marín-Moreno, Sara Canoyra, Natalia Fernández-Borges, Juan Carlos Espinosa, Juan María Torres
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 1, p 21 (2023)
Neurodegenerative diseases (NDs) are some of the most important health challenges modern medicine and advanced societies face. Indeed, the number of patients affected by one of these illnesses will increase in the following years at the same rate tha
Externí odkaz:
https://doaj.org/article/79e054b8b79f41be83d344b84cd25c02
Autor:
Franc Llorens, Katrin Thüne, Waqas Tahir, Eirini Kanata, Daniela Diaz-Lucena, Konstantinos Xanthopoulos, Eleni Kovatsi, Catharina Pleschka, Paula Garcia-Esparcia, Matthias Schmitz, Duru Ozbay, Susana Correia, Ângela Correia, Ira Milosevic, Olivier Andréoletti, Natalia Fernández-Borges, Ina M. Vorberg, Markus Glatzel, Theodoros Sklaviadis, Juan Maria Torres, Susanne Krasemann, Raquel Sánchez-Valle, Isidro Ferrer, Inga Zerr
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-21 (2017)
Abstract Background YKL-40 (also known as Chitinase 3-like 1) is a glycoprotein produced by inflammatory, cancer and stem cells. Its physiological role is not completely understood but YKL-40 is elevated in the brain and cerebrospinal fluid (CSF) in
Externí odkaz:
https://doaj.org/article/ecd452e7a5af49e1a47d32c0f9339fd5
Autor:
Natalia Fernández-Borges, Juan Carlos Espinosa, Alba Marín-Moreno, Patricia Aguilar-Calvo, Emmanuel A. Asante, Tetsuyuki Kitamoto, Shirou Mohri, Olivier Andréoletti, Juan María Torres
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 9, Pp 1522-1530 (2017)
Bovine spongiform encephalopathy (BSE) is the only known zoonotic prion that causes variant Creutzfeldt-Jakob disease (vCJD) in humans. The major risk determinant for this disease is the polymorphic codon 129 of the human prion protein (Hu-PrP), wher
Externí odkaz:
https://doaj.org/article/adfbf9e2b4344c33b8f0a6e3907f10d8
Autor:
Franc Llorens, Katrin Thüne, Beata Sikorska, Matthias Schmitz, Waqas Tahir, Natalia Fernández-Borges, Maria Cramm, Nadine Gotzmann, Margarita Carmona, Nathalie Streichenberger, Uwe Michel, Saima Zafar, Anna-Lena Schuetz, Ashish Rajput, Olivier Andréoletti, Stefan Bonn, Andre Fischer, Pawel P. Liberski, Juan Maria Torres, Isidre Ferrer, Inga Zerr
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-20 (2017)
Abstract Sporadic Creutzfeldt-Jakob disease (sCJD) is the most prevalent form of human prion disease and it is characterized by the presence of neuronal loss, spongiform degeneration, chronic inflammation and the accumulation of misfolded and pathoge
Externí odkaz:
https://doaj.org/article/2e50321168ab46359a8ddcd179c4d0d2
Autor:
Hasier Eraña, Jorge M Charco, Michele A Di Bari, Carlos M Díaz-Domínguez, Rafael López-Moreno, Enric Vidal, Ezequiel González-Miranda, Miguel A Pérez-Castro, Sandra García-Martínez, Susana Bravo, Natalia Fernández-Borges, Mariví Geijo, Claudia D'Agostino, Joseba Garrido, Jifeng Bian, Anna König, Boran Uluca-Yazgi, Raimon Sabate, Vadim Khaychuk, Ilaria Vanni, Glenn C Telling, Henrike Heise, Romolo Nonno, Jesús R Requena, Joaquín Castilla
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008117 (2019)
The resolution of the three-dimensional structure of infectious prions at the atomic level is pivotal to understand the pathobiology of Transmissible Spongiform Encephalopathies (TSE), but has been long hindered due to certain particularities of thes
Externí odkaz:
https://doaj.org/article/215467d1d4f44efeb809d884605f8666
Autor:
Alejandro M Sevillano, Natalia Fernández-Borges, Neelam Younas, Fei Wang, Saioa R Elezgarai, Susana Bravo, Ester Vázquez-Fernández, Isaac Rosa, Hasier Eraña, David Gil, Sonia Veiga, Enric Vidal, Melissa L Erickson-Beltran, Esteban Guitián, Christopher J Silva, Romolo Nonno, Jiyan Ma, Joaquín Castilla, Jesús R Requena
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006797 (2018)
Very solid evidence suggests that the core of full length PrPSc is a 4-rung β-solenoid, and that individual PrPSc subunits stack to form amyloid fibers. We recently used limited proteolysis to map the β-strands and connecting loops that make up the
Externí odkaz:
https://doaj.org/article/a5a65062a45e40f184b776930d9e28d0
Autor:
Franc Llorens, Katrin Thüne, Eulàlia Martí, Eirini Kanata, Dimitra Dafou, Daniela Díaz-Lucena, Ana Vivancos, Orr Shomroni, Saima Zafar, Matthias Schmitz, Uwe Michel, Natalia Fernández-Borges, Olivier Andréoletti, José Antonio Del Río, Juana Díez, Andre Fischer, Stefan Bonn, Theodoros Sklaviadis, Juan Maria Torres, Isidre Ferrer, Inga Zerr
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006802 (2018)
Increasing evidence indicates that microRNAs (miRNAs) are contributing factors to neurodegeneration. Alterations in miRNA signatures have been reported in several neurodegenerative dementias, but data in prion diseases are restricted to ex vivo and a
Externí odkaz:
https://doaj.org/article/af99f18480054466853a78bc909aede2