Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Natalia F Smirnova"'
1
Akademický článek
Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease
Autor: Jie Jia, Thomas M Conlon, Rim SJ Sarker, Demet Taşdemir, Natalia F Smirnova, Barkha Srivastava, Stijn E Verleden, Gizem Güneş, Xiao Wu, Cornelia Prehn, Jiaqi Gao, Katharina Heinzelmann, Jutta Lintelmann, Martin Irmler, Stefan Pfeiffer, Michael Schloter, Ralf Zimmermann, Martin Hrabé de Angelis, Johannes Beckers, Jerzy Adamski, Hasan Bayram, Oliver Eickelberg, Ali Önder Yildirim
Publikováno v: EMBO Molecular Medicine, Vol 10, Iss 5, Pp 1-17 (2018)
Abstract The development of chronic obstructive pulmonary disease (COPD) pathogenesis remains unclear, but emerging evidence supports a crucial role for inducible bronchus‐associated lymphoid tissue (iBALT) in disease progression. Mechanisms underl
Externí odkaz: https://doaj.org/article/97fa922cf1de46cda5b806cfa389d804
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2
Akademický článek
A minor tweak in transplant surgery protocols alters the cellular landscape of the arterial wall during transplant vasculopathy
Autor: Laura Mickiewicz, Rana Zahreddine, Kévin Cormier, Sophie Peries, Arnaud Del Bello, Muriel Laffargue, Natalia F. Smirnova
Publikováno v: Frontiers in Transplantation, Vol 3 (2024)
IntroductionTransplant vasculopathy (TV) is a major complication after solid organ transplantation, distinguished by an arterial intimal thickening that obstructs the vascular lumen and leads to organ rejection. To date, TV remains largely untreatabl
Externí odkaz: https://doaj.org/article/add249b854d849e5881b5989984a7b1d
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3
Akademický článek
The different natural estrogens promote endothelial healing through distinct cell targets
Autor: Morgane Davezac, Rana Zahreddine, Melissa Buscato, Natalia F. Smirnova, Chanaelle Febrissy, Henrik Laurell, Silveric Gilardi-Bresson, Marine Adlanmerini, Philippe Liere, Gilles Flouriot, Rachida Guennoun, Muriel Laffargue, Jean-Michel Foidart, Françoise Lenfant, Jean-François Arnal, Raphaël Métivier, Coralie Fontaine
Publikováno v: JCI Insight, Vol 8, Iss 5 (2023)
The main estrogen, 17β-estradiol (E2), exerts several beneficial vascular actions through estrogen receptor α (ERα) in endothelial cells. However, the impact of other natural estrogens such as estriol (E3) and estetrol (E4) on arteries remains poo
Externí odkaz: https://doaj.org/article/cee391bdb2374d7ba32e1f7c699de3f8
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4
Akademický článek
Single-cell transcriptome mapping identifies a local, innate B cell population driving chronic rejection after lung transplantation
Autor: Natalia F. Smirnova, Kent Riemondy, Marta Bueno, Susan Collins, Pavan Suresh, Xingan Wang, Kapil N. Patel, Carlyne Cool, Melanie Königshoff, Nirmal S. Sharma, Oliver Eickelberg
Publikováno v: JCI Insight, Vol 7, Iss 18 (2022)
Bronchiolitis obliterans syndrome (BOS) is the main reason for poor outcomes after lung transplantation (LTx). We and others have recently identified B cells as major contributors to BOS after LTx. The extent of B cell heterogeneity and the relative
Externí odkaz: https://doaj.org/article/96c9037e12a14bf89a9c5ed4e05661c0
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5
A historical view of estrogen effect on arterial endothelial healing: From animal models to medical implication
Autor: Coralie Fontaine, Melissa Buscato, Morgane Davezac, Jean-François Arnal, Rana Zahreddine, Natalia F. Smirnova, Marine Adlanmerini, Daniel Henrion, Muriel Laffargue, Françoise Lenfant
Publikováno v: Atherosclerosis. 338:30-38
Endothelial barrier integrity is required for maintaining vascular homeostasis and fluid balance between the circulation and surrounding tissues. In contrast, abnormalities of endothelial cell function and loss of the integrity of the endothelial mon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ada727ace1ec99314e01d66667dc0e
https://doi.org/10.1016/j.atherosclerosis.2021.10.013
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6
Single cell transcriptome mapping identifies a local innate B cell population driving local antibody production and chronic rejection after lung transplantation
Autor: Susan Collins, Kent Riemondy, K. Patel, Natalia F. Smirnova, Nirmal S. Sharma, Oliver Eickelberg, Melanie Koenigshoff, Carlyne D. Cool
Bronchiolitis obliterans syndrome (BOS) due to chronic rejection is the main reason for poor outcomes after lung transplantation (LTx). We and others have recently identified B cells as major contributors to BOS after LTx. The extent of B cell hetero
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ee69513c648593d5015927bb5bfa0f5
https://doi.org/10.1101/2021.02.16.431278
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7
Noncatalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage
Autor: Régis Blaise, Damien Ramel, Natalia F. Smirnova, Emilio Hirsch, Alessandra Ghigo, Muriel Laffargue, Nicole Malet, Pierre Vincent, Stéphanie Gayral, Adrien Lupieri, Isabelle Limon, Marie-Kerguelen Sarthou
Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2020, pp.jcs.245969. ⟨10.1242/jcs.245969⟩
Journal of Cell Science, Company of Biologists, 2020, 133 (13), pp.jcs245969. ⟨10.1242/jcs.245969⟩
Journal of Cell Science, 2020, pp.jcs.245969. ⟨10.1242/jcs.245969⟩
International audience; Arterial remodeling in hypertension and intimal hyperplasia involves inflammation and disrupted flow, both of which contribute to smooth muscle cell dedifferentiation and proliferation. In this context, our previous results id
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd503acdf34174addc47312f4a6bfb5
https://hal.archives-ouvertes.fr/hal-02817436
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8
Tamoxifen Accelerates Endothelial Healing by Targeting ERα in Smooth Muscle Cells
Autor: Alexia Vinel, Marie-Ange Renault, Françoise Lenfant, Emeline Lhuillier, Adrien Lupieri, Alain-Pierre Gadeau, Natalia F. Smirnova, Melissa Buscato, Morgane Davezac, Coralie Fontaine, Romain Solinhac, Raphaël Métivier, Gilles Flouriot, Emilie Vessieres, Rana Zahreddine, Jean-François Arnal, Daniel Henrion, Muriel Laffargue
Publikováno v: Circulation Research
Circulation Research, 2020, 127 (12), pp.1473-1487. ⟨10.1161/CIRCRESAHA.120.317062⟩
Circulation Research, American Heart Association, 2020, 127 (12), pp.1473-1487. ⟨10.1161/CIRCRESAHA.120.317062⟩
Circulation Research, American Heart Association, 2020, ⟨10.1161/CIRCRESAHA.120.317062⟩
Circ Res
Rationale: Tamoxifen prevents the recurrence of breast cancer and is also beneficial against bone demineralization and arterial diseases. It acts as an ER (estrogen receptor) α antagonist in ER-positive breast cancers, whereas it mimics the protecti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26b3f12b32b3f5dc38ddf5ff3260c78
https://hal.science/hal-03040722/document
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9
Preservation with α1-antitrypsin improves primary graft function of murine lung transplants
Autor: Oliver Eickelberg, Carmela Morrone, Natalia F. Smirnova, Jessica Götzfried, A. O. Yildirim, Brice Korkmaz, Dieter E. Jenne
Publikováno v: The Journal of Heart and Lung Transplantation
J. Heart Lung Transpl. 37, 1021-1028 (2018)
BACKGROUND: Vascular damage and primary graft dysfunction increase with prolonged preservation times of transplanted donor lungs. Hence, storage and conservation of donated lungs in protein-free, dextran-containing electrolyte solutions, like Perfade
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398ad545a981cf33f59d006f1d2e4222
http://europepmc.org/articles/PMC6078707
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