Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Natalia E. Broude"'
Autor:
Irina V. Smolina, Natalia E. Broude
Publikováno v:
Cancer Biology & Medicine, Vol 12, Iss 3, Pp 143-149 (2015)
Cancer cells differ from normal cells in various parameters, and these differences are caused by genomic mutations and consequential altered gene expression. The genetic and functional heterogeneity of tumor cells is a major challenge in cancer resea
Externí odkaz:
https://doaj.org/article/ac301442cd454f6e9b382618dc11744e
Publikováno v:
Pharmaceuticals, Vol 4, Iss 3, Pp 494-508 (2011)
Many genetic and infectious diseases can be targeted at the RNA level as RNA is more accessible than DNA. We seek to develop new approaches for detection and tracking RNA in live cells, which is necessary for RNA-based diagnostics and therapy. We rec
Externí odkaz:
https://doaj.org/article/92696c9b82784c7f9aa075d7b6556bc4
Autor:
Harry Driscoll, Natalia E. Broude, Charles R. Cantor, Feng Ding, Yingjie Sun, Paul Toran, Irina V. Smolina
Publikováno v:
Cell Research. 24:894-897
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd42f46de046cee6d84351bb12debf9
https://doi.org/10.1038/cr.2014.47
https://doi.org/10.1038/cr.2014.47
Autor:
Natalia E. Broude
Publikováno v:
Molecular Microbiology. 80:1137-1147
Studies of gene expression at the single cell level in live bacterial cells represent a new and fertile area of research providing real-time, spatially specified information that cannot be obtained by techniques relying on large cell populations. Bef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c5165d6b3d00319bc23b269e47c7140
https://doi.org/10.1111/j.1365-2958.2011.07652.x
https://doi.org/10.1111/j.1365-2958.2011.07652.x
Publikováno v:
Pharmaceuticals
Volume 4
Issue 3
Pages 494-508
Pharmaceuticals, Vol 4, Iss 3, Pp 494-508 (2011)
Volume 4
Issue 3
Pages 494-508
Pharmaceuticals, Vol 4, Iss 3, Pp 494-508 (2011)
Many genetic and infectious diseases can be targeted at the RNA level as RNA is more accessible than DNA. We seek to develop new approaches for detection and tracking RNA in live cells, which is necessary for RNA-based diagnostics and therapy. We rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c9911fd9ad91e39eb80a82bc88f40f
http://europepmc.org/articles/PMC4053799
http://europepmc.org/articles/PMC4053799
Autor:
Feng Ding, Natalia E. Broude, Shantanu Sharma, Vadim V. Demidov, Nikolay V. Dokholyan, Poornima Chalasani
Publikováno v:
RNA. 14:1164-1173
RNA molecules with novel functions have revived interest in the accurate prediction of RNA three-dimensional (3D) structure and folding dynamics. However, existing methods are inefficient in automated 3D structure prediction. Here, we report a robust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2da7257495b0134bffa8999155854f
https://doi.org/10.1261/rna.894608
https://doi.org/10.1261/rna.894608
Publikováno v:
Nature Methods. 4:421-427
We describe a technique for the detection and localization of RNA transcripts in living cells. The method is based on fluorescent-protein complementation regulated by the interaction of a split RNA-binding protein with its corresponding RNA aptamer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432a6975a3d2819aaf0c0eba7c1b7412
https://doi.org/10.1038/nmeth1023
https://doi.org/10.1038/nmeth1023
Autor:
Natalia E. Broude, Irina V. Smolina
Publikováno v:
RNA Scaffolds ISBN: 9781493927296
The spectrum of RNA functions in the cell continues to widen and new types of RNA molecules continue to be discovered. However, methods to access and manipulate endogenous RNAs in live cells are limited. Here we describe a universal technique for lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb5660444cc9826e0a0ff71121c150c
https://doi.org/10.1007/978-1-4939-2730-2_7
https://doi.org/10.1007/978-1-4939-2730-2_7
Autor:
Carlos Witte-Hoffmann, Natalia E. Broude, Poornima Chalasani, Nikolay V. Dokholyan, Feng Ding, Yong Yu, Hung Wei Yiu, Charles R. Cantor, Vadim V. Demidov
Publikováno v:
Proceedings of the National Academy of Sciences. 103:2052-2056
Fluorescent proteins have proven to be excellent reporters and biochemical sensors with a wide range of applications. In a split form, they are not fluorescent, but their fluorescence can be restored by supplementary protein–protein or protein–nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f3547ddad860673abc3f759413c9da
https://doi.org/10.1073/pnas.0511078103
https://doi.org/10.1073/pnas.0511078103
Autor:
Natalia E. Broude
Publikováno v:
Trends in Biotechnology. 20:249-256
The specific structural features of stem-loop (hairpin) DNA constructs provide increased specificity of target recognition. Recently, several robust assays have been developed that exploit the potential of structurally constrained oligonucleotides to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cef28106c51ad73194fa157e08b374d
https://doi.org/10.1016/s0167-7799(02)01942-x
https://doi.org/10.1016/s0167-7799(02)01942-x