Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Natalia Dworak"'
Autor:
Chun-Song Yang, Kasey Jividen, Teddy Kamata, Natalia Dworak, Luke Oostdyk, Bartlomiej Remlein, Yasin Pourfarjam, In-Kwon Kim, Kang-Ping Du, Tarek Abbas, Nicholas E. Sherman, David Wotton, Bryce M. Paschal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Androgen receptor (AR) signaling is regulated by multiple post-translational modifications. Here, the authors identify the writer and reader enzymes for AR ADP-ribosylation and show how they modulate AR signaling output in prostate cancer cells.
Externí odkaz:
https://doaj.org/article/4e3161d87a9e495bb19ec9d697ca2a8c
Publikováno v:
eLife, Vol 9 (2020)
We have previously demonstrated that checkpoint kinase 2 (CHK2) is a critical negative regulator of androgen receptor (AR) transcriptional activity, prostate cancer (PCa) cell growth, and androgen sensitivity. We have now uncovered that the AR direct
Externí odkaz:
https://doaj.org/article/314ac06112aa4f8599d533907962de2d
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
We have previously demonstrated that checkpoint kinase 2 (CHK2) is a critical negative regulator of androgen receptor (AR) transcriptional activity, prostate cancer (PCa) cell growth, and androgen sensitivity. We have now uncovered that the AR direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1752bec1bd14ff7e4d05380e40c6aa
https://elifesciences.org/articles/51378
https://elifesciences.org/articles/51378
Autor:
Teddy Kamata, Luke T. Oostdyk, Chun-Song Yang, In-Kwon Kim, Yasin Pourfarjam, Natalia Dworak, Kasey Jividen, Tarek Abbas, Bryce M. Paschal, Bartlomiej Remlein, Kang-Ping Du, David Wotton, Nicholas E. Sherman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Androgen signaling through the androgen receptor (AR) directs gene expression in both normal and prostate cancer cells. Androgen regulates multiple aspects of the AR life cycle, including its localization and post-translational modification, but unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f387dd0c6b375a219c58452d942dbee
https://pubmed.ncbi.nlm.nih.gov/33976187
https://pubmed.ncbi.nlm.nih.gov/33976187
We have previously demonstrated that checkpoint kinase 2 (CHK2) is a critical negative regulator of androgen receptor (AR) transcriptional activity, prostate cancer (PCa) cell growth, and androgen sensitivity. We have now uncovered that the AR direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07c33c8f4daa300e0fafb8eced849ea6
https://doi.org/10.1101/759142
https://doi.org/10.1101/759142
Autor:
Natalia Dworak, Bryce M. Paschal, Luke T. Oostdyk, Kasey Jividen, Teddy Kamata, Adam Spencer, Chun-Song Yang
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781493991945
Methods in Molecular Biology ISBN: 9781493991945
ADP-ribosylation is a post-translational modification generated by members of the superfamily of ADP-ribosyltransferases, known as the Parp enzymes. Depending on the superfamily member, Parp enzymes can conjugate a single ADP-ribose to a protein subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ef8930cafd8df944a12727b7c86dc9
https://pubmed.ncbi.nlm.nih.gov/31041742
https://pubmed.ncbi.nlm.nih.gov/31041742
Autor:
Bryce M. Paschal, Luke T. Oostdyk, Leonard Shank, Natalia Dworak, Nicholas E. Sherman, Kasey Jividen
The discovery and validation of protein-protein interactions provides a knowledge base that is critical for defining protein networks and how they underpin the biology of the cell. Identification of protein interactions that are highly transient, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3977bf87c79f85c8cf2b17354b3e03
https://europepmc.org/articles/PMC7087410/
https://europepmc.org/articles/PMC7087410/
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01549e4da4e027bef39bdcbc6e138bb6
https://doi.org/10.1530/endoabs.54.oc7
https://doi.org/10.1530/endoabs.54.oc7
Autor:
Joshua B. Kelley, Dawid Makosa, Chelsi J. Snow, Natalia Dworak, Mandovi Chatterjee, Chun-Song Yang, Kasey Jividen, William C. Simke, Isaac G Johnson, Bryce M. Paschal
Publikováno v:
Aging Cell
The Ran GTPase regulates nuclear import and export by controlling the assembly state of transport complexes. This involves the direct action of RanGTP, which is generated in the nucleus by the chromatin‐associated nucleotide exchange factor, RCC1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5ba5b8ead2e1665bcbe8d0f40c252d
https://pubmed.ncbi.nlm.nih.gov/30565836
https://pubmed.ncbi.nlm.nih.gov/30565836