Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Natalia Duque-Wilckens"'
Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors
Autor:
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Yan Wu, Adam J. Moeser, George I. Mias, Alfred J. Robison, Jin He
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Yuen Gao et al. characterize deficits in brain morphology, behavior, and gene expression following genetic ablation of the histone methyltransferase, ASH1L, during brain development in mice. Their results provide new insight into links between ASH1L
Externí odkaz:
https://doaj.org/article/4b96d495f04d482b9a52d8c90fd24875
Autor:
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Adam J. Moeser, George I. Mias, Alfred J. Robison, Yi Zhang, Jin He
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103742- (2022)
Summary: Recent clinical studies report that chromosomal 12q24.31 microdeletions are associated with autism spectrum disorder (ASD) and intellectual disability (ID). However, the causality and underlying mechanisms linking 12q24.31 microdeletions to
Externí odkaz:
https://doaj.org/article/7c4859cbe5774588b7eece70ffe4b2db
Autor:
Alfred J. Robison, Andrew L. Eagle, Cynthia L. Jordan, Elizabeth S. Williams, Claire E. Manning, Ashlyn Swift-Gallant, Natalia Duque-Wilckens, Sadhana Chinnusamy, Adam J. Moeser, Gina M. Leinninger
Publikováno v:
Biol Psychiatry
Background Depression affects women nearly twice as often as men, but the neurobiological underpinnings of this discrepancy are unclear. Preclinical studies in male mice suggest that activity of ventral hippocampus (vHPC) neurons projecting to the nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163b5368165cb4d39cc9fef0c2be998e
https://doi.org/10.1016/j.biopsych.2019.08.006
https://doi.org/10.1016/j.biopsych.2019.08.006
Autor:
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Adam J. Moeser, George I. Mias, Alfred J. Robison, Yi Zhang, Jin He
Publikováno v:
iScience
iScience, Vol 25, Iss 2, Pp 103742-(2022)
iScience, Vol 25, Iss 2, Pp 103742-(2022)
Summary Recent clinical studies report that chromosomal 12q24.31 microdeletions are associated with autism spectrum disorder (ASD) and intellectual disability (ID). However, the causality and underlying mechanisms linking 12q24.31 microdeletions to A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eca179dfc0b9976e6d8f5bf053aa747
https://pubmed.ncbi.nlm.nih.gov/35128353
https://pubmed.ncbi.nlm.nih.gov/35128353
Autor:
Zakaria Dairi, Robby E. Teis, Natalia Duque-Wilckens, Frauke Stoelting, Alfred J. Robison, Alex Douma, Adam J. Moeser, Sonia Khalid, Kyan Thelen, Nidia Maradiaga, Erika Sarno
Exposure to early life adversity (ELA) in the form of physical and/or psychological abuse or neglect increases the risk of developing psychiatric and inflammatory disorders later in life. It has been hypothesized that exposure to ELA results in persi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39b474b881726c4cdb80ba186d0d5763
https://doi.org/10.1101/2021.09.17.460793
https://doi.org/10.1101/2021.09.17.460793
Autor:
Alfred J. Robison, Mohammad B. Aljazi, George I. Mias, Yi Zhang, Jin He, Adam J. Moeser, Natalia Duque-Wilckens, Yuen Gao
Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental diseases associated with various genetic mutations. Recent clinical studies report that chromosomal 12q24.31 microdeletions are associated with human ASD/ID. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90a231eef0e66f224f96722604d58e42
https://doi.org/10.1101/2021.09.13.459918
https://doi.org/10.1101/2021.09.13.459918
Autor:
Natalia Duque-Wilckens, Robert Teis, Erika Sarno, Frauke Stoelting, Sonia Khalid, Zakaria Dairi, Alex Douma, Nidia Maradiaga, Stina Hench, Christine D. Dharshika, Kyan M. Thelen, Brian Gulbransen, A.J. Robison, Adam J. Moeser
Publikováno v:
Brain, behavior, and immunity. 103
Exposure to early life adversity (ELA) in the form of physical and/or psychological abuse or neglect increases the risk of developing psychiatric and inflammatory disorders later in life. It has been hypothesized that exposure to ELA results in persi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b84cf957effb0c601f73b13e7c953cc
https://pubmed.ncbi.nlm.nih.gov/35339629
https://pubmed.ncbi.nlm.nih.gov/35339629
Publikováno v:
Psychoneuroendocrinology. 140:105709
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b94262a20358153e02827a15c888b32
https://doi.org/10.1016/j.psyneuen.2022.105709
https://doi.org/10.1016/j.psyneuen.2022.105709
Autor:
Natalia Duque-Wilckens, Vanessa A. Minie, Emily C. Wright, Radmila Petric, Stephanie Ramos-Maciel, Brian C. Trainor
Domesticated mice and rats have shown to be powerful model systems for biomedical research, but there are cases in which the biology of species is a poor match for the hypotheses under study. The California mouse (Peromyscus californicus) has unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b34f87ecec38dbc0c705f7d09d048277
https://doi.org/10.1101/2021.01.05.425454
https://doi.org/10.1101/2021.01.05.425454
Autor:
Adam J. Moeser, Natalia Duque-Wilckens, Jin He, George I. Mias, Alfred J. Robison, Yingying Wu, Yuen Gao, Mohammad B. Aljazi
Autism spectrum disorder (ASD) is a neurodevelopmental disease associated with various gene mutations. Recent genetic and clinical studies report that mutations of the epigenetic gene ASH1L are highly associated with human ASD and intellectual disabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::940ce117775fd47db79eb1106429c231
https://doi.org/10.1101/2020.11.16.377259
https://doi.org/10.1101/2020.11.16.377259