Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Natalia Cristina Fernandez"'
Autor:
Natalia eAlonso, Carlos Daniel Zappia, Maia eCabrera, Carlos Alberto Davio, Carina eShayo, Federico eMonczor, Natalia Cristina Fernandez
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Histamine mediates numerous functions acting through its four receptor subtypes all belonging to the large family of seven transmembrane G-protein coupled receptors (GPCRs). In particular, histamine H2 receptor (H2R) is mainly involved in gastric aci
Externí odkaz:
https://doaj.org/article/df1a7afd723d4353ae1f09b949c6ba10
Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines
Autor:
Carlos Davio, Georgina Alexandra Cardama, Natalia Cristina Fernandez, Emiliana Beatriz Echeverría, Pablo Lorenzano Menna, Federico Remes Lenicov, Maia Diana Eliana Cabrera, Nazareno González
Publikováno v:
Oncotarget
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Rac1 GTPase has long been recognized as a critical regulatory protein in different cellular and molecular processes involved in cancer progression, including acute myeloid leukemia. Here we show the antitumoral activity of ZINC69391 and 1A-116, two c
Autor:
Ezequiel Ivan Juritz, Carlos Davio, Valeria Burghi, Maia Diana Eliana Cabrera, Ana Julia Velez Rueda, Lucas Fabian, Natalia Cristina Fernandez, Emiliana Beatriz Echeverría, Pablo Lorenzano Menna
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Aims: G protein-coupled receptor (GPCR) kinases (GRKs) are mainly involved in the desensitization of GPCRs. Among them, GRK2 has been described to be upregulated in many pathological conditions and its crucial role in cardiac hypertrophy, hypertensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9651545a8df9023e4588d49f6d4e5252
https://linkinghub.elsevier.com/retrieve/pii/S0024320519307994
https://linkinghub.elsevier.com/retrieve/pii/S0024320519307994
Autor:
Fernando P. Dominici, Marina C. Muñoz, Máximo Hernán Sosa, Emiliana Beatriz Echeverría, Natalia Cristina Fernandez, Federico Monczor, Valeria Burghi, Diego Tomás Quiroga, Carlos Davio
Publikováno v:
Frontiers in Pharmacology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Pharmacology, Vol 10 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Pharmacology, Vol 10 (2019)
The MasR receptor (MasR) is an orphan G protein-coupled receptor proposed as a candidate for mediating the angiotensin (Ang)-converting enzyme 2-Ang-(1-7) protective axis of renin-angiotensin system. This receptor has been suggested to participate in
Autor:
Carina Shayo, Antonela Díaz Nebreda, Natalia Gómez, Federico Monczor, Natalia Cristina Fernandez, Carlos Daniel Zappia, Sonia Ripoll, Valeria Burghi, Emiliana Beatriz Echeverría, Carlos Davio
Publikováno v:
European Journal of Pharmacology. 896:173913
Histamine H1 receptor ligands used clinically as antiallergics rank among the most widely prescribed and over-the-counter drugs in the world. They exert the therapeutic actions by blocking the effects of histamine, due to null or negative efficacy to
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
H1 and H2 histamine receptor antagonists, although developed many decades ago, are still effective for the treatment of allergic and gastric acid-related conditions. This article focuses on novel aspects of the pharmacology and molecular mechanisms o
Autor:
Ana Sahores, Alejandro Enrique Carozzo, Alejandra I. Attorresi, Agustín Yaneff, Nicolás Di Siervi, Federico Monczor, Natalia Cristina Fernandez, Carina Shayo, Martín Carlos Abba, Federico Diez, Carlos Davio, Ángela Rodríguez-González, Natalia Gómez
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Pancreatic cancer is one of the most lethal types of tumors with no effective therapy available; is currently the third leading cause of cancer in developed countries; and is predicted to become the second deadliest cancer in the United States by 203
Autor:
Érica Guilhen Mario, Marina C. Muñoz, Michael Bader, Verónica Gabriela Piazza, Yamila Belén Gándola, Robson A.S. Santos, Natalia Cristina Fernandez, Janaina F Braga, Fernando P. Dominici, Diego Tomás Quiroga, Valeria Burghi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0183278 (2017)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 12, Iss 8, p e0183278 (2017)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Mas receptor (MasR) is a G protein-coupled receptor proposed as a candidate formediating the angiotensin (Ang)-converting enzyme 2-Ang (1-7) protective axis ofrenin-angiotensin system. Because the role of this receptor is not definitively clarified,d
Publikováno v:
Experimental Neurology. 248:262-274
Oligodendrocytes are the cells producing the myelin membrane around the axons in the central nervous system and, although apotransferrin (aTf) is required for oligodendrocyte differentiation, the underlying mechanisms are not fully understood. Fyn ty
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783319581927
Acute myeloid leukemia (AML) consists in a cancer of early hematopoietic cells arising in the bone marrow, most often of those cells that would turn into white blood cells (except lymphocytes). Chemotherapy is the treatment of choice for AML but one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0dc2576923c824512a3a1d6bdaf6ec
https://doi.org/10.1007/164_2016_8
https://doi.org/10.1007/164_2016_8