Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Natalia Castro-Lopez"'
Autor:
Lukas M. du Plooy, Calla L. Telzrow, Connie B. Nichols, Corinna Probst, Natalia Castro-Lopez, Floyd L. Wormley, J. Andrew Alspaugh
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Cellular responses to external stress allow microorganisms to adapt to a vast array of environmental conditions, including infection sites. The molecular mechanisms behind these responses are studied to gain insight into microbial pathogenes
Externí odkaz:
https://doaj.org/article/6afdb1943cbe404d9dfbeb5018096d34
Autor:
Natalia Castro-Lopez, Althea Campuzano, Elysa Mdalel, Difernando Vanegas, Ashok Chaturvedi, Phung Nguyen, Mark Pulse, Astrid E. Cardona, Floyd L. Wormley
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Cryptococcosis, caused by fungi of the genus Cryptococcus, manifests in a broad range of clinical presentations, including severe pneumonia and disease of the central nervous system (CNS) and other tissues (bone and skin). Immune deficiency
Externí odkaz:
https://doaj.org/article/7be10c535b3947b0ab7650db1c44648c
Autor:
Carlos Alberto Peláez-Jaramillo, Maria Del Pilar Jiménez-Alzate, Pedronel Araque-Marin, Chiung-Yu Hung, Natalia Castro-Lopez, Garry T. Cole
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Coccidioides is a soil-borne fungal pathogen and causative agent of a human respiratory disease (coccidioidomycosis) endemic to semi-desert regions of southwestern United States, Mexico, Central and South America. Aerosolized arthroconidia inhaled by
Externí odkaz:
https://doaj.org/article/4a51da4a83bf432aa0726898290a3d4a
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract Background Cryptococcus neoformans, the causative agent of cryptococcosis, causes ~ 181,000 deaths annually, with males having a higher incidence of disease than females (7M:3F). The reason for this sex bias remains unclear. We hypothesized
Externí odkaz:
https://doaj.org/article/e3ccd65fdfab49ffa9311b3aa473613d
Autor:
Camaron R. Hole, Chrissy M. Leopold Wager, Natalia Castro-Lopez, Althea Campuzano, Hong Cai, Karen L. Wozniak, Yufeng Wang, Floyd L. Wormley
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Wormley and colleagues present data showing that vaccine strategies can be devised to prime dendritic cells to respond in a memory-like fashion upon subsequent exposure to a pathogen.
Externí odkaz:
https://doaj.org/article/8b6de08e40944ad089c3cdc3d7cca731
Autor:
Althea Campuzano, Natalia Castro-Lopez, Amanda J. Martinez, Michal A. Olszewski, Anutosh Ganguly, Chrissy Leopold Wager, Chiung-Yu Hung, Floyd L. Wormley
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Caspase recruitment domain-containing protein 9 (CARD9) is a critical adaptor molecule triggered by the interaction of C-type lectin receptors (CLRs) with carbohydrate motifs found in fungi. Consequently, clinical and animal studies indicate
Externí odkaz:
https://doaj.org/article/6c21d53c72894c5282dc76e76f285e1a
Autor:
Calla L. Telzrow, Connie B. Nichols, Natalia Castro-Lopez, Floyd L. Wormley, J. Andrew Alspaugh
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Arrestins, a structurally specialized and functionally diverse group of proteins, are central regulators of adaptive cellular responses in eukaryotes. Previous studies on fungal arrestins have demonstrated their capacity to modulate diverse
Externí odkaz:
https://doaj.org/article/46e71b2e9087448086405dcc06adbbf3
Autor:
Chrissy M Leopold Wager, Camaron R Hole, Althea Campuzano, Natalia Castro-Lopez, Hong Cai, Marley C Caballero Van Dyke, Karen L Wozniak, Yufeng Wang, Floyd L Wormley
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007358 (2018)
Development of vaccines against opportunistic infections is difficult as patients most at risk of developing disease are deficient in aspects of the adaptive immune system. Here, we utilized an experimental immunization strategy to induce innate memo
Externí odkaz:
https://doaj.org/article/9b8f5e1d82764f04b5dcd73c9a68a8b2
Autor:
Marley C. Caballero Van Dyke, Ashok K. Chaturvedi, Sarah E. Hardison, Chrissy M. Leopold Wager, Natalia Castro-Lopez, Camaron R. Hole, Karen L. Wozniak, Floyd L. Wormley
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no clinically available vaccine to prevent cryptococcosis. Mice given an
Externí odkaz:
https://doaj.org/article/8a156071758c4a378bfe53d5b02194d2
Autor:
Althea Campuzano, Natalia Castro-Lopez, Karen L Wozniak, Chrissy M Leopold Wager, Floyd L Wormley
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169347 (2017)
C-type lectin receptors (CLRs) are diverse, trans-membrane proteins that function as pattern recognition receptors (PRRs) which are necessary for orchestrating immune responses against pathogens. CLRs have been shown to play a major role in recogniti
Externí odkaz:
https://doaj.org/article/180d81c69f9d431ca7bacb379b35e34a