Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Natalia C. Ferreira"'
Autor:
Simote T. Foliaki, Benjamin Schwarz, Bradley R. Groveman, Ryan O. Walters, Natalia C. Ferreira, Christina D. Orrù, Anna Smith, Aleksandar Wood, Olivia M. Schmit, Phoebe Freitag, Jue Yuan, Wenquan Zou, Catharine M. Bosio, James A. Carroll, Cathryn L. Haigh
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-23 (2021)
Abstract The neuro-physiological properties of individuals with genetic pre-disposition to neurological disorders are largely unknown. Here we aimed to explore these properties using cerebral organoids (COs) derived from fibroblasts of individuals wi
Externí odkaz:
https://doaj.org/article/6bd0dd66c2cd46cbb517d6bd6b03291d
Autor:
Natalia C. Ferreira, Jorge M. Charco, Jakob Plagenz, Christina D. Orru, Nathanial D. Denkers, Michael A. Metrick, Andrew G. Hughson, Karen A. Griffin, Brent Race, Edward A. Hoover, Joaquín Castilla, Tracy A. Nichols, Michael W. Miller, Byron Caughey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Efforts to contain the spread of chronic wasting disease (CWD), a fatal, contagious prion disease of cervids, would be aided by the availability of additional diagnostic tools. RT-QuIC assays allow ultrasensitive detection of prion seeds in
Externí odkaz:
https://doaj.org/article/161a06b194b3492ea12e6770ee888250
Autor:
Bradley R. Groveman, Natalia C. Ferreira, Simote T. Foliaki, Ryan O. Walters, Clayton W. Winkler, Brent Race, Andrew G. Hughson, Gianluigi Zanusso, Cathryn L. Haigh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Creutzfeldt–Jakob Disease (CJD) is a fatal, currently incurable, neurodegenerative disease. The search for candidate treatments would be greatly facilitated by the availability of human cell-based models of prion disease. Recently, an indu
Externí odkaz:
https://doaj.org/article/349388bbff72452db46c3047ea9cc10f
Autor:
CLAUDIA P. FIGUEIREDO, NATALIA C. FERREIRA, GISELLE F. PASSOS, ROBSON DA COSTA, FERNANDA S. NEVES, CLARICE S.C. MACHADO, ALESSANDRA MASCARELLO, LOUISE D. CHIARADIA-DELATORRE, PATRÍCIA D. NEUENFELDT, RICARDO J. NUNES, YRAIMA CORDEIRO
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 87, Iss 2 suppl, Pp 1421-1434 (2015)
An altered form of the cellular prion protein, the PrPScor PrPRes, is implicated in the occurrence of the still untreatable transmissible spongiform encephalopathies. We have previously synthesized and characterized aromatic compounds that inhibit pr
Externí odkaz:
https://doaj.org/article/7c9d0eadc0b24f0895791b4cc5cc305c
Autor:
Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012175 (2024)
Prions or prion-like aggregates such as those composed of PrP, α-synuclein, and tau are key features of proteinopathies such as prion, Parkinson's and Alzheimer's diseases, respectively. Their presence on solid surfaces may be biohazardous under som
Externí odkaz:
https://doaj.org/article/e41f9f194a98464797ac114a7b488335
Autor:
Juli Thomaz de Souza, Marcos F. Minicucci, Natália C. Ferreira, Bertha F. Polegato, Marina Politi Okoshi, Gabriel P. Modolo, Bethan E. Phillips, Philip J. Atherton, Kenneth Smith, Daniel Wilkinson, Adam Gordon, Suzana E. Tanni, Vladimir Eliodoro Costa, Maria Fernanda P. Fernandes, Silméia G. Zanati Bazan, Leonardo A. M. Zornoff, Rodrigo Bazan, Sérgio A. Rupp de Paiva, Paula Schmidt Azevedo
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Stroke is a leading cause of mortality and disability, and its sequelae are associated with inadequate food intake which can lead to sarcopenia. The aim of this study is to verify the effectiveness of creatine supplementation on f
Externí odkaz:
https://doaj.org/article/b7c4e571be834c63978cab4bcbe3a743
Autor:
Daniela Vicente Bavaresco, Natalia C. Ferreira, Luciane Bisognin Ceretta, Lisiane Tuon, Priscyla Waleska Simões, Karin Martins Gomes, Graziela Amboni
Publikováno v:
Inova Saúde. 5:30
O Diabetes Mellitus consiste em uma doença crônica que ocorre quando o pâncreas não produz insulina o suficiente, ou o organismo não é capaz de utilizar efetivamente a insulina produzida, o Diabetes Mellitus esta sendo considerado um problema d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fe4445499427c725599daee23cc382
https://doi.org/10.18616/is.v5i1.2336.30-41
https://doi.org/10.18616/is.v5i1.2336.30-41
Autor:
Natalia C Ferreira, Icaro A Marques, Wesley A Conceição, Bruno Macedo, Clarice S Machado, Alessandra Mascarello, Louise Domeneghini Chiaradia-Delatorre, Rosendo Augusto Yunes, Ricardo José Nunes, Andrew G Hughson, Lynne D Raymond, Pedro G Pascutti, Byron Caughey, Yraima Cordeiro
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84531 (2014)
The prion protein (PrP) is implicated in the Transmissible Spongiform Encephalopathies (TSEs), which comprise a group of fatal neurodegenerative diseases affecting humans and other mammals. Conversion of cellular PrP (PrP(C)) into the scrapie form (P
Externí odkaz:
https://doaj.org/article/43799d36574b4265a3fe221bb978ffb9