Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Natalia Briones"'
Autor:
Jessica D. Lang, Tuong Vi V. Nguyen, Maren K. Levin, Page E. Blas, Heather L. Williams, Esther San Roman Rodriguez, Natalia Briones, Claudius Mueller, William Selleck, Sarah Moore, Victoria L. Zismann, William P.D. Hendricks, Virginia Espina, Joyce O’Shaughnessy
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract Background A subset of triple-negative breast cancers (TNBCs) have homologous recombination deficiency with upregulation of compensatory DNA repair pathways. PIKTOR, a combination of TAK-228 (TORC1/2 inhibitor) and TAK-117 (PI3Kα inhibitor)
Externí odkaz:
https://doaj.org/article/52d8e016d5974151b746534d27914afc
Autor:
Jennifer Barrila, Shameema F. Sarker, Nicole Hansmeier, Shanshan Yang, Kristina Buss, Natalia Briones, Jin Park, Richard R. Davis, Rebecca J. Forsyth, C. Mark Ott, Kevin Sato, Cristine Kosnik, Anthony Yang, Cheryl Shimoda, Nicole Rayl, Diana Ly, Aaron Landenberger, Stephanie D. Wilson, Naoko Yamazaki, Jason Steel, Camila Montano, Rolf U. Halden, Tom Cannon, Sarah L. Castro-Wallace, Cheryl A. Nickerson
Publikováno v:
npj Microgravity, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Spaceflight uniquely alters the physiology of both human cells and microbial pathogens, stimulating cellular and molecular changes directly relevant to infectious disease. However, the influence of this environment on host–pathogen interac
Externí odkaz:
https://doaj.org/article/0a444f5908f9404283b41f24e25ddf2d
Autor:
Shukmei Wong, E J Ehrhart, Samuel Stewart, Victoria Zismann, Jacob Cawley, Rebecca Halperin, Natalia Briones, Keith Richter, Karthigayini Sivaprakasam, Nieves Perdigones, Tania Contente-Cuomo, Salvatore Facista, Jeffrey M Trent, Muhammed Murtaza, Chand Khanna, William P D Hendricks
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0264986 (2022)
Cancer genomic heterogeneity presents significant challenges for understanding oncogenic processes and for cancer's clinical management. Variation in driver mutation frequency between patients with the same tumor type as well as within an individual
Externí odkaz:
https://doaj.org/article/62e231b6cdc64d4faee96910a1df5788
Autor:
Ignazio S. Piras, Nieves Perdigones, Victoria Zismann, Natalia Briones, Salvatore Facista, José Luis Rivera, Elizabeth Rozanski, Cheryl A. London, William P. D. Hendricks
Publikováno v:
Genes, Vol 11, Iss 11, p 1313 (2020)
Canine gastric dilatation-volvulus (GDV) is a common life-threatening condition occurring primarily in large and giant breeds with a 3.9% to 36.7% lifetime risk. The genetic correlates of GDV have not previously been systematically explored. We under
Externí odkaz:
https://doaj.org/article/a65d18613b87454da2751b6dfb3fb7bd
Autor:
William P. D. Hendricks, Natalia Briones, Rebecca F. Halperin, Salvatore Facista, Paul R. Heaton, Daruka Mahadevan, Suwon Kim
Publikováno v:
Cancers, Vol 11, Iss 10, p 1566 (2019)
The therapeutic HER2-targeting antibody trastuzumab has been shown to elicit tumor immune response in a subset of HER2-positive (HER2+) breast cancer. We performed genomic and immunohistochemical profiling of tumors from eight patients who have compl
Externí odkaz:
https://doaj.org/article/e3261a1773234c0b9e19ecbeede83c3d
Autor:
Natalia Briones, Maren K Levin, Jessica D. Lang, Virginia Espina, Victoria Zismann, Claudius Mueller, Joyce O'Shaughnessy, Priscilla Ontiveros, Esther San Roman Rodriguez, Rick Wenstrup, William P.D. Hendricks, Tiziano Pramparo
Publikováno v:
Cancer Research. 81:PS11-25
BACKGROUND: A subset of TNBCs have homologous recombination deficiency with upregulation of compensatory DNA repair pathways. The combination of TAK-228 and TAK-117 (PIKTOR), investigational oral TORC1/2 and PI3Kα selective inhibitors, respectively,
Autor:
Anthony N. Karnezis, Shary Yuting Chen, Jeffrey M. Trent, Anne Marie Mes-Masson, Natalia Briones, Pilar Ramos, Christine Chow, Winnie Yang, David G. Huntsman, William P.D. Hendricks, Bernard E. Weissman, Yemin Wang, Tjalling Bosse, C Blake Gilks
Publikováno v:
Gynecol Oncol
Gynecologic Oncology, 160(2), 568-578. ACADEMIC PRESS INC ELSEVIER SCIENCE
Gynecologic oncology, vol 160, iss 2
Gynecologic Oncology, 160(2), 568-578. ACADEMIC PRESS INC ELSEVIER SCIENCE
Gynecologic oncology, vol 160, iss 2
Objective. The development of effective cancer treatments depends on the availability of cell lines that faithfully recapitulate the cancer in question. This study definitively re-assigns the histologic identities of two ovarian cancer cell lines, CO
Autor:
Muhammed Murtaza, Rebecca F. Halperin, Keith Richter, Samuel Stewart, E. J. Ehrhart, Victoria Zismann, Salvatore Facista, Shukmei Wong, Tania Contente-Cuomo, Nieves Perdigones, Jacob Cawley, Jeffrey M. Trent, Karthigayini Sivaprakasam, Chand Khanna, Natalia Briones, William P.D. Hendricks
Cancer genomic heterogeneity presents significant challenges for understanding oncogenic processes and for cancer’s clinical management. Variation in driver mutation frequency between patients with the same tumor type as well as within individual p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5770e1a682ba07591f38f4d69a0157cc
https://doi.org/10.1101/2020.11.15.380048
https://doi.org/10.1101/2020.11.15.380048
Autor:
Victoria Zismann, José Luis Rivera, Cheryl A. London, Nieves Perdigones, Ignazio S. Piras, Natalia Briones, Elizabeth A. Rozanski, William P.D. Hendricks, Salvatore Facista
Publikováno v:
Genes
Genes, Vol 11, Iss 1313, p 1313 (2020)
Volume 11
Issue 11
Genes, Vol 11, Iss 1313, p 1313 (2020)
Volume 11
Issue 11
Canine gastric dilatation-volvulus (GDV) is a common life-threatening condition occurring primarily in large and giant breeds with a 3.9% to 36.7% lifetime risk. The genetic correlates of GDV have not previously been systematically explored. We under
Autor:
Aaron Killian, Maren K Levin, Natalia Briones, Alison Barron, Jeffrey P. Lamont, Matthew J. McBride, William P.D. Hendricks, Tuoc Dao, Jonathan M. Ghergurovich, Virginia Espina, Claudius Mueller, Xiaoyang Su, Salvatore Facista, Joyce O'Shaughnessy, Alexis J. Cowan, Jessica D. Lang, Joshua D. Rabinowitz, Esther San Roman Rodriguez, Daniel D. Von Hoff
Publikováno v:
Med (N Y)
Summary Background Upregulated glucose metabolism is a common feature of tumors. Glucose can be broken down by either glycolysis or the oxidative pentose phosphate pathway (oxPPP). The relative usage within tumors of these catabolic pathways remains