Latent Mycobacterium tuberculosis Infection Is Associated With a Higher Frequency of Mucosal-Associated Invariant T and Invariant Natural Killer T Cells

Autor: Dominic Paquin-Proulx, Priscilla R. Costa, Cassia G. Terrassani Silveira, Mariana P. Marmorato, Natalia B. Cerqueira, Matthew S. Sutton, Shelby L. O’Connor, Karina I. Carvalho, Douglas F. Nixon, Esper G. Kallas

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Increasing drug resistance and the lack of an effective vaccine are the main factors contributing to Mycobacterium tuberculosis (Mtb) being a major cause of death globally. Despite intensive research efforts, it is not well understood why some indivi

Externí odkaz: https://doaj.org/article/bc3008eb4bfb4fadafa584ab5605eb04

HLA-C downregulation by HIV-1 adapts to host HLA genotype.

Autor: Nathaniel D Bachtel, Gisele Umviligihozo, Suzanne Pickering, Talia M Mota, Hua Liang, Gregory Q Del Prete, Pramita Chatterjee, Guinevere Q Lee, Rasmi Thomas, Mark A Brockman, Stuart Neil, Mary Carrington, Bosco Bwana, David R Bangsberg, Jeffrey N Martin, Esper G Kallas, Camila S Donini, Natalia B Cerqueira, Una T O'Doherty, Beatrice H Hahn, R Brad Jones, Zabrina L Brumme, Douglas F Nixon, Richard Apps

Publikováno v: PLoS Pathogens, Vol 14, Iss 9, p e1007257 (2018)

HIV-1 can downregulate HLA-C on infected cells, using the viral protein Vpu, and the magnitude of this downregulation varies widely between primary HIV-1 variants. The selection pressures that result in viral downregulation of HLA-C in some individua

Externí odkaz: https://doaj.org/article/fd77a141723449b993740096f7b2aca0

Immune effects of Lactobacillus casei Shirota in treated HIV-infected patients with poor CD4+ T-cell recovery

Autor: Priscilla R. Costa, Simone de Barros Tenore, Zelinda Nakagawa, Natalia B. Cerqueira, Lucas A M Franco, Esper G. Kallas, Ester Cerdeira Sabino, Vivian Iida Avelino-Silva, Jorge Kalil

Publikováno v: AIDS. 34:381-389

Background HIV infection leads to depletion of intestinal CD4+ T cells, mucosal barrier dysfunction, increased gut permeability and microbial translocation even among patients on suppressive ART. Previous studies suggest probiotics may help restore i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f252211ded7f07542975b50c1efe04
https://doi.org/10.1097/qad.0000000000002420

Predictors of mortality in patients with yellow fever: an observational cohort study

Autor: Yeh-Li Ho, Gabriela B F Diniz, Renata Buccheri, Priscilla R. Costa, Nathalia C. Santiago Souza, José Eduardo Levi, Esper G. Kallas, Luiz Gonzaga Francisco de Assis Barros D'Elia Zanella, Natalia B. Cerqueira, Carlos Henrique Valente Moreira, Anna Carla P Castiñeiras, Daniel Joelsons, Alvino Maestri, Alice Tung Wan Song, Vivian Iida Avelino-Silva, Ingra Morales Claro, Mariana P Marmorato, Igor C. Borges, Ester Cerdeira Sabino, Juliana Zanatta de Carvalho Dias

Publikováno v: The Lancet. Infectious diseases. 19(7)

Summary Background Yellow fever virus infection results in death in around 30% of symptomatic individuals. The aim of this study was to identify predictors of death measured at hospital admission in a cohort of patients admitted to hospital during th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26058d68b95ecc4d112eb668871903fb
https://pubmed.ncbi.nlm.nih.gov/31559956

Latent Mycobacterium tuberculosis Infection Is Associated With a Higher Frequency of Mucosal-Associated Invariant T and Invariant Natural Killer T Cells

Autor: Mariana P Marmorato, Shelby L. O’Connor, Matthew S. Sutton, Cassia G. T. Silveira, Karina I. Carvalho, Esper G. Kallas, Priscilla R. Costa, Douglas F. Nixon, Natalia B. Cerqueira, Dominic Paquin-Proulx

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology, Vol 9 (2018)

Increasing drug resistance and the lack of an effective vaccine are the main factors contributing to Mycobacterium tuberculosis (Mtb) being a major cause of death globally. Despite intensive research efforts, it is not well understood why some indivi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e19df14f960436560588ace1bd1e5df