Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Natalia Arruda-Costa"'
Autor:
Ariane de J. Sousa-Batista, Natalia Arruda-Costa, Wallace Pacienza-Lima, Felipe Carvalho-Gondim, Rosiane F. Santos, Silvia A. G. Da-Silva, Maria Inês Ré, Bartira Rossi-Bergmann
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 51 (2022)
Current chemotherapy of cutaneous leishmaniasis (CL) is based on repeated systemic or intralesional administration of drugs that often cause severe toxicity. Previously, we demonstrated the therapeutic potential of biodegradable poly(lactic-co-glycol
Externí odkaz:
https://doaj.org/article/64c83a06095b40629526de0285d86ba4
Autor:
Douglas O Escrivani, Rebecca L Charlton, Marjolly B Caruso, Gabriela A Burle-Caldas, Maria Paula G Borsodi, Russolina B Zingali, Natalia Arruda-Costa, Marcos V Palmeira-Mello, Jéssica B de Jesus, Alessandra M T Souza, Bárbara Abrahim-Vieira, Stefanie Freitag-Pohl, Ehmke Pohl, Paul W Denny, Bartira Rossi-Bergmann, Patrick G Steel
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009951 (2021)
With current drug treatments failing due to toxicity, low efficacy and resistance; leishmaniasis is a major global health challenge that desperately needs new validated drug targets. Inspired by activity of the natural chalcone 2',6'-dihydroxy-4'-met
Externí odkaz:
https://doaj.org/article/97dcebeea4914662b9ca60f477d72118
Autor:
Franceline Reynaud, Natalia Arruda-Costa, Ariane de Jesus Sousa-Batista, Patrick G. Steel, Douglas O Escrivani, Bartira Rossi-Bergmann
Publikováno v:
Parasitology
Parasitology, 2020, Vol.147(9), pp.1032-1037 [Peer Reviewed Journal]
Parasitology, 2020, Vol.147(9), pp.1032-1037 [Peer Reviewed Journal]
Cutaneous leishmaniasis (CL) is a major health problem in many countries and its current treatment involves multiple parenteral injections with toxic drugs and requires intensive health services. Previously, the efficacy of a single subcutaneous inje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64d91c29aaecc35f3478f5cad2e0cda
https://europepmc.org/articles/PMC10317656/
https://europepmc.org/articles/PMC10317656/
Anti-parasitic effect of the diuretic and Na+-ATPAse inhibitor furosemide in cutaneous leishmaniasis
Autor:
E E Almeida-Amaral, José Roberto Meyer-Fernandes, Bartira Rossi-Bergmann, Douglas O Escrivani, Natalia Arruda-Costa
Publikováno v:
Parasitology. 144:1375-1383
SUMMARYLeishmania amazonensispromastigotes are known to express furosemide (Lasix®)-sensitiveP-type membrane Na+-ATPase. In the present study, furosemide activity was studied in intracellular amastigotes and infected BALB/c mice to investigate its e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541f54de2916548f1a7fdb2cea84619e
https://doi.org/10.1017/s0031182017000695
https://doi.org/10.1017/s0031182017000695
Publikováno v:
Drug Development and Industrial Pharmacy
Drug Development and Industrial Pharmacy, Taylor & Francis, 2018, 44 (9), pp.1473-1480. ⟨10.1080/03639045.2018.1461903⟩
Drug Development and Industrial Pharmacy, Taylor & Francis, 2018, 44 (9), pp.1473-1480. ⟨10.1080/03639045.2018.1461903⟩
International audience; Current chemotherapy of cutaneous leishmaniasis (CL), even the mildest forms, encompasses multiple and painful injections with toxic drugs that cause systemic adverse effects. Recently, we showed the promising use of poly(lact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2851b95cec175b8ddb41eb9c2919c28b
https://hal-mines-albi.archives-ouvertes.fr/hal-01984692/file/improved-drug-loading.pdf
https://hal-mines-albi.archives-ouvertes.fr/hal-01984692/file/improved-drug-loading.pdf
Autor:
Ariane de Jesus Sousa-Batista, Natalia Arruda-Costa, Wallace Pacienza-Lima, Maria Inês Ré, Camila A. B. Falcão, Bartira Rossi-Bergmann
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2018, 62 (3), pp.art. e01822-17. ⟨10.1128/AAC.01822-17⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2018, 62 (3), pp.art. e01822-17. ⟨10.1128/AAC.01822-17⟩
Conventional chemotherapy of cutaneous leishmaniasis (CL) is based on multiple parenteral or intralesional injections with systemically toxic drugs. Aiming at a single-dose localized therapy, biodegradable poly(lactic-co-glycolic acid) (PLGA) micropa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4880676e410f1185d0ce2efe6d3683d1
https://hal-mines-albi.archives-ouvertes.fr/hal-01712186/document
https://hal-mines-albi.archives-ouvertes.fr/hal-01712186/document