Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Natalia A. Syrota"'
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 20, Iss 2, Pp 27-51 (2022)
Aim. To analyze and summarize the synthetic potential of 1,2,3-triazole-4(5)-amines as efficient building blocks in the synthesis of triazolo-annulated pyridine, azine and azepine systems. Results and discussion. Original literature sources revealin
Externí odkaz:
https://doaj.org/article/5633e45214624081941674431785b23c
Autor:
Natalia A. Syrota, A. V. Bol’but, Mykhailo V. Vovk, Igor I. Chernobaev, Oleksandr S. Liavinets, Sergiy V. Kemskiy
Publikováno v:
Chemistry of Heterocyclic Compounds. 57:841-847
4-(N-Boc-amino)-1Н-1,2,3-triazolecarbothioamides, obtained by a sequential treatment of 4-(N-Boc-amino)-1Н-1,2,3-triazoles with n-BuLi and alkyl isothiocyanates at –78÷–60°C, reacted with ethyl bromoacetate, forming the respective 4-(N-Boc-am
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1048-1053
4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes upon heating under reflux in acetic acid in the presence of pyrrolidine react with cycloalkanones, acetylacetone, 1,3-cyclohexanediones, and malononitrile resulting in annulation of the pyridine ring wit
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:1092-1097
The corresponding ethyl 5-carbonylglycinates were synthesized by condensation of 4-(Boc-amino)-1,2,3-triazole-5-carboxylic acids with ethyl glycinate hydrochloride. They were intramolecularly cyclized with the selective formation of 1,4,6,7-tetrahydr
Publikováno v:
Chemistry of Heterocyclic Compounds. 54:789-795
5-Amino-N-(2,2-dimethoxyethyl)-1Н-1,2,3-triazole-4-carboxamides in formic acid were subjected to intramolecular cyclization to 5-hydroxy[1,2,3]triazolo[4,5-е][1,4]diazepines, which were converted by treatment with S-nucleophiles to 5-thio-functiona