Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Natalia A. Stefanova"'
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2374 (2024)
Background: It is believed that alterations in the functioning of the cytochrome P450 (CYP), which participates in metabolic transformations of endogenous polyunsaturated fatty acids (PUFAs) (with the formation of cardioprotective or cardiotoxic prod
Externí odkaz:
https://doaj.org/article/b879d370d01a45f1809f3a881df68a0a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1462 (2023)
It has been suggested that functional traits of the adult brain—all of which are established early in life—may affect the brain’s susceptibility to Alzheimer’s disease (AD). Results of our previous studies on senescence-accelerated OXYS rats,
Externí odkaz:
https://doaj.org/article/be0fe4a5fb9b41b7a94d39de267e2e5a
Autor:
Ekaterina A. Rudnitskaya, Tatiana A. Kozlova, Alena O. Burnyasheva, Anna E. Tarasova, Tatiana M. Pankova, Marina V. Starostina, Natalia A. Stefanova, Nataliya G. Kolosova
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Aging is the major risk factor of the most common (∼95% of cases) sporadic Alzheimer’s disease (AD). Accumulating data indicate middle age as a critical period for the relevant pathological processes, however, the question of when AD starts to de
Externí odkaz:
https://doaj.org/article/7162feb079b6451a9eea47ce7817906b
Autor:
Ekaterina A. Rudnitskaya, Alena O. Burnyasheva, Tatiana A. Kozlova, Daniil A. Peunov, Nataliya G. Kolosova, Natalia A. Stefanova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1134 (2022)
Astrocytes and microglia are the first cells to react to neurodegeneration, e.g., in Alzheimer’s disease (AD); however, the data on changes in glial support during the most common (sporadic) type of the disease are sparse. Using senescence-accelera
Externí odkaz:
https://doaj.org/article/3d0e8a671fa84b89ba9ae8484e68c317
Autor:
Natalia A. Stefanova, Kseniya Yi Maksimova, Ekaterina A. Rudnitskaya, Natalia A. Muraleva, Nataliya G. Kolosova
Publikováno v:
BMC Genomics, Vol 19, Iss S3, Pp 51-63 (2018)
Abstract Background Cerebrovascular dysfunction plays a critical role in the pathogenesis of Alzheimer’s disease (AD): the most common cause of dementia in the elderly. The involvement of neurovasculature disorders in the progression of AD is now i
Externí odkaz:
https://doaj.org/article/1f226daf26224dd89e05387d2e1b2236
Autor:
Ekaterina A. Rudnitskaya, Tatiana A. Kozlova, Alena O. Burnyasheva, Natalia A. Stefanova, Nataliya G. Kolosova
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 823 (2021)
Sporadic Alzheimer’s disease (AD) is a severe disorder of unknown etiology with no definite time frame of onset. Recent studies suggest that middle age is a critical period for the relevant pathological processes of AD. Nonetheless, sufficient data
Externí odkaz:
https://doaj.org/article/37543dbbf808423ab62e0775c8381721
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1058 (2021)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia worldwide, with no cure. There is growing interest in mitogen-activated protein kinases (MAPKs) as possible pathogenesis-related therapeutic
Externí odkaz:
https://doaj.org/article/a66b207e622841d18b431a796f74506c
Autor:
Alena O. Burnyasheva, Tatiana A. Kozlova, Natalia A. Stefanova, Nataliya G. Kolosova, Ekaterina A. Rudnitskaya
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 6986 (2020)
There is a growing body of evidence that interventions like cognitive training or exercises prior to the manifestation of Alzheimer’s disease (AD) symptoms may decelerate cognitive decline. Nonetheless, evidence of prevention or a delay of dementia
Externí odkaz:
https://doaj.org/article/156685b6702343c5b807c2864d827805
Publikováno v:
Antioxidants, Vol 9, Iss 8, p 676 (2020)
Alzheimer’s disease (AD) is the most common type of dementia and is currently incurable, and mitogen-activated protein kinase (MAPK) p38 is implicated in the pathogenesis of AD. p38 MAPK inhibition is considered a promising strategy against AD, but
Externí odkaz:
https://doaj.org/article/3d34f2613a724bf8b4006c1cee0d6014
Publikováno v:
Economy, Governance and Lave Basis. :74-79