Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natalia A. Elkina"'
Autor:
Yanina V. Burgart, Natalia A. Elkina, Evgeny V. Shchegolkov, Olga P. Krasnykh, Galina F. Makhaeva, Galina A. Triandafilova, Sergey Yu. Solodnikov, Natalia P. Boltneva, Elena V. Rudakova, Nadezhda V. Kovaleva, Olga G. Serebryakova, Mariya V. Ulitko, Sophia S. Borisevich, Natalia A. Gerasimova, Natalia P. Evstigneeva, Sergey A. Kozlov, Yuliya V. Korolkova, Artem S. Minin, Anna V. Belousova, Evgenii S. Mozhaitsev, Artem M. Klabukov, Victor I. Saloutin
Publikováno v:
Molecules, Vol 28, Iss 1, p 59 (2022)
4-Arylhydrazinylidene-5-(polyfluoroalkyl)pyrazol-3-ones (4-AHPs) were found to be obtained by the regiospecific cyclization of 2-arylhydrazinylidene-3-(polyfluoroalkyl)-3-oxoesters with hydrazines, by the azo coupling of 4-nonsubstituted pyrazol-5-ol
Externí odkaz:
https://doaj.org/article/e03f60e649344091824c96142959378b
Autor:
Natalia A. Elkina, Maria V. Grishchenko, Evgeny V. Shchegolkov, Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Sofya V. Lushchekina, Tatiana Y. Astakhova, Eugene V. Radchenko, Vladimir A. Palyulin, Ekaterina F. Zhilina, Anastasiya N. Perminova, Luka S. Lapshin, Yanina V. Burgart, Victor I. Saloutin, Rudy J. Richardson
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1551 (2022)
Alzheimer’s disease (AD) is considered a modern epidemic because of its increasing prevalence worldwide and serious medico-social consequences, including the economic burden of treatment and patient care. The development of new effective therapeuti
Externí odkaz:
https://doaj.org/article/407988391fe84cfd910efe4df0c33cf1
Autor:
Evgeny V. Shchegolkov, Olga G. Serebryakova, Galina F. Makhaeva, Natalia A. Elkina, Ya. V. Burgart, Sofya V. Lushchekina, Viktor I. Saloutin, N. P. Boltneva
Publikováno v:
Russian Chemical Bulletin. 70:567-572
A series of new adamantyl and citronellyl 4,4,4-trifluoro-2-arylhydrazinylidene-3-oxo-butanoates was synthesized. The synthesized compounds in nanomolar concentrations selectively inhibit carboxylesterase, while their activity is independent of the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659876c524b9c59621acd80abcbe35e1
https://doi.org/10.1007/s11172-021-3126-2
https://doi.org/10.1007/s11172-021-3126-2
Autor:
Evgeny V. Shchegolkov, Elena V. Rudakova, Olga G. Serebryakova, Victor I. Saloutin, Natalia А. Elkina, Yanina V. Burgart, Olga P. Krasnykh, Sergey Yu. Solodnikov, Galina F. Makhaeva, V. V. Maslova, Galina A. Triandafilova
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:199-207
New pyrazolo[1,5-a]pyrimidinones functionalized with the tolylhydrazone fragment were obtained as a result of cyclization of 3-oxo-2-(tolylhydrazinylidene) esters with 3-aminopyrazoles. In this case, methyl- and trifluoromethyl-containing derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927b0954a996dae84bf023514c929ab5
https://doi.org/10.1007/s10593-020-02652-1
https://doi.org/10.1007/s10593-020-02652-1
Autor:
Natalia A. Elkina, Evgeny V. Shchegolkov, Yanina V. Burgart, Victor I. Saloutin, Natalia P. Boltneva, Elena V. Rudakova, Galina F. Makhaeva
Publikováno v:
AIP Conference Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5b40d3f2ee2561c9e79773a30c50d38
https://doi.org/10.1063/5.0069215
https://doi.org/10.1063/5.0069215
Autor:
Natalia A. Elkina, Evgeny V. Shchegolkov, Yanina V. Burgart, Natalia A. Agafonova, Anastasia N. Perminova, Natalia A. Gerasimova, Galina F. Makhaeva, Elena V. Rudakova, Nadezhda V. Kovaleva, Natalia P. Boltneva, Olga G. Serebryakova, Sophia S. Borisevich, Natalia P. Evstigneeva, Natalia V. Zilberberg, Nikolai V. Kungurov, Victor I. Saloutin
Publikováno v:
Journal of Fluorine Chemistry. 254:109935
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb7442f2e844f904648b0b9b875741ba
https://doi.org/10.1016/j.jfluchem.2021.109935
https://doi.org/10.1016/j.jfluchem.2021.109935
Autor:
Nadezhda V. Kovaleva, Vladimir A. Palyulin, Natalia A. Elkina, N. P. Boltneva, Alexey A. Terentiev, Victor I. Saloutin, Rudy J. Richardson, Evgeny V. Shchegolkov, Olga G. Serebryakova, Yanina V. Burgart, Galina F. Makhaeva, Sofya V. Lushchekina, Tatyana S. Stupina, Sergey O. Bachurin, Eugene V. Radchenko, Elena V. Rudakova
Publikováno v:
European Journal of Medicinal Chemistry. 218:113385
An expanded series of alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates (HOPs) 3 was obtained via Cu(OAc)2-catalyzed azo coupling. All were nanomolar inhibitors of carboxylesterase (CES), while moderate or weak inhibitors of acetylcholin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7954c29e7b2c8a4f5ec8eac34684260
https://doi.org/10.1016/j.ejmech.2021.113385
https://doi.org/10.1016/j.ejmech.2021.113385
Autor:
N. P. Boltneva, Galina F. Makhaeva, Sergey O. Bachurin, Elena V. Rudakova, Evgeny V. Shchegolkov, Sofya V. Lushchekina, Olga G. Serebryakova, Yanina V. Burgart, Victor I. Saloutin, Rudy J. Richardson, Natalia A. Elkina, Olga G. Khudina
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(23)
A series of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids was synthesized via dealkylation of ethyl 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoates under the action of a Lewis acid. Under the same conditions, ethyl 2-arylhydrazinyli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd8f5f62639d07d2fb0afbe41340d08
https://pubmed.ncbi.nlm.nih.gov/31640885
https://pubmed.ncbi.nlm.nih.gov/31640885
Autor:
Sofya V. Lushchekina, Galina F. Makhaeva, Vladimir A. Palyulin, Evgeny V. Shchegolkov, Olga G. Serebryakova, Victor I. Saloutin, Nadezhda V. Kovaleva, Rudy J. Richardson, Eugene V. Radchenko, Natalia A. Elkina, Sergey O. Bachurin, Yanina V. Burgart, Elena V. Rudakova, N. P. Boltneva
Publikováno v:
Bioorganic chemistry. 91
To search for effective and selective inhibitors of carboxylesterase (CES), a series of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher or natural alcohol moieties was synthesized via pre-transesterification of ethyl trifluoroac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e98573cdfd3087d4173a8d5f567fdf6
https://pubmed.ncbi.nlm.nih.gov/31323527
https://pubmed.ncbi.nlm.nih.gov/31323527
Autor:
V. V. Maslova, Galina A. Triandafilova, Yanina V. Burgart, Maria A. Misiurina, Natalia A. Elkina, Vladimir V. Zarubaev, Sergey S. Solodnikov, Evgeny V. Shchegolkov, Alexander V. Slita, Olga P. Krasnykh, Anna A. Muryleva, Victor I. Saloutin
Publikováno v:
Journal of Fluorine Chemistry. 240:109648
The reaction of polyfluoroalkyl-containing 2-tolylhydrazinylidene-1,3-diketones with 3-aminopyrazoles depending on their structure can proceed as N,N-cyclization to form 5-RF- and 7-RF-regioisomeric pyrazolo[1,5-a]pyrimidines (at that haloform cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a2adbc427f149c07cf35ed51bf3673
https://doi.org/10.1016/j.jfluchem.2020.109648
https://doi.org/10.1016/j.jfluchem.2020.109648