Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Natalia, Pacienza"'
Autor:
Ricardo Malvicini, Diego Santa-Cruz, Anna Maria Tolomeo, Maurizio Muraca, Gustavo Yannarelli, Natalia Pacienza
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291589 (2023)
In the last few years, extracellular vesicles (EVs) have become of great interest due to their potential as biomarkers, drug delivery systems, and, in particular, therapeutic agents. However, there is no consensus on which is the best way to isolate
Externí odkaz:
https://doaj.org/article/bd4f2f6133864fb08a883baeec6cc035
Autor:
Andrea Papait, Antonietta Rosa Silini, Maria Gazouli, Ricardo Malvicini, Maurizio Muraca, Lorraine O’Driscoll, Natalia Pacienza, Wei Seong Toh, Gustavo Yannarelli, Peter Ponsaerts, Ornella Parolini, Günther Eissner, Michela Pozzobon, Sai Kiang Lim, Bernd Giebel
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Perinatal tissues, mainly the placenta and umbilical cord, contain a variety of different somatic stem and progenitor cell types, including those of the hematopoietic system, multipotent mesenchymal stromal cells (MSCs), epithelial cells and amnion e
Externí odkaz:
https://doaj.org/article/9cc59fafb0fc4698b80df76a66adc772
Autor:
Luciana M. Domínguez, Bárbara Bueloni, Ma. José Cantero, Milagros Albornoz, Natalia Pacienza, Celeste Biani, Carlos Luzzani, Santiago Miriuka, Mariana García, Catalina Atorrasagasti, Gustavo Yannarelli, Juan Bayo, Esteban Fiore, Guillermo Mazzolini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9586 (2023)
New therapeutic options for liver cirrhosis are needed. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have emerged as a promising tool for delivering therapeutic factors in regenerative medicine. Our aim is to establish a new thera
Externí odkaz:
https://doaj.org/article/aa4cb0a8044346c9acb47226f6ca28aa
Autor:
Natalia Pacienza, Ryang Hwa Lee, Eun-Hye Bae, Dong-ki Kim, Qisong Liu, Darwin J. Prockop, Gustavo Yannarelli
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 67-76 (2019)
Extracellular vesicles (EVs) play key roles in cell biology and may provide new clinical diagnostics and therapies. However, it has proven difficult to develop protocols for their purification and characterization. One of the major barriers in the fi
Externí odkaz:
https://doaj.org/article/edf9fc30177047ae834b933eb1960fa5
Autor:
Diego Santa-Cruz, Natalia Pacienza, Carla Zilli, Eduardo Pagano, Karina Balestrasse, Gustavo Yannarelli
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 549-557 (2017)
Heme oxygenase-1 (HO-1) plays a protective role against oxidative stress in plants. The mechanisms regulating its expression, however, remain unclear. Here we studied the methylation state of a GC rich HO-1 promoter region and the expression of sever
Externí odkaz:
https://doaj.org/article/391617ec54fd403a91358f32da7504ae
Autor:
Natalia Pacienza, Diego Santa-Cruz, Ricardo Malvicini, Oscar Robledo, Gastón Lemus-Larralde, Alejandro Bertolotti, Martín Marcos, Gustavo Yannarelli
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Lung transplantation is a lifesaving therapy for people living with severe, life-threatening lung disease. The high mortality rate among patients awaiting transplantation is mainly due to the low percentage of lungs that are deemed acceptable for imp
Externí odkaz:
https://doaj.org/article/3fe9cd329040469bbe73f47d9e66badb
Autor:
Mazzolini, Luciana M. Domínguez, Bárbara Bueloni, Ma. José Cantero, Milagros Albornoz, Natalia Pacienza, Celeste Biani, Carlos Luzzani, Santiago Miriuka, Mariana García, Catalina Atorrasagasti, Gustavo Yannarelli, Juan Bayo, Esteban Fiore, Guillermo
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9586
New therapeutic options for liver cirrhosis are needed. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have emerged as a promising tool for delivering therapeutic factors in regenerative medicine. Our aim is to establish a new thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0009c40570e834a3f6b87a26477c0ba7
Autor:
Gustavo Yannarelli, Claudia Noemí Martini, Maria del Carmen Vila, Fernando Nicolas Sosa, Ricardo Malvicini, Natalia Pacienza
Publikováno v:
Journal of Physiology and Biochemistry. 77:601-611
Alendronate, a bisphosphonate used to prevent osteoporosis, stimulates osteogenesis but impairs adipogenesis. Different clinical trials suggest that the incidence of diabetes may be lower in patients treated with alendronate. Taking into account the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03a05daf1bbccc48a4668d21dd0d785
https://doi.org/10.1007/s13105-021-00826-9
https://doi.org/10.1007/s13105-021-00826-9
Autor:
Gustavo Yannarelli, Natalia Pacienza, Sonia Montanari, Diego Santa-Cruz, Sowmya Viswanathan, Armand Keating
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189131 (2017)
Mesenchymal stem/stromal cells (MSCs) are in numerous cell therapy clinical trials, including for injured myocardium. Acquisition of cardiomyocyte characteristics by MSCs may improve cardiac regeneration but the mechanisms regulating this process are
Externí odkaz:
https://doaj.org/article/ba43487a51c24e8c9bda1f92315f75b1
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3268 (2019)
Mechanisms mediating mesenchymal stromal/stem cells’ (MSCs) multipotency are unclear. Although the expression of the pluripotency factor OCT4 has been detected in MSCs, whether it has a functional role in adult stem cells is still controversial. We
Externí odkaz:
https://doaj.org/article/4e84a6d08fa1428eb767524bdab72c17