Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Natalia, Ninkina"'
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 881 (2024)
The malfunctioning of the brain synucleins is associated with pathogenesis of Parkinson’s disease. Synucleins’ ability to modulate various pre-synaptic processes suggests their modifying effects on the electroencephalogram (EEG) recorded from dif
Externí odkaz:
https://doaj.org/article/cd85c9eae82b4e6dafcd5148a7aa986f
Autor:
Natalia Ninkina, Michail S. Kukharsky
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2330 (2023)
Extensive studies of α-synuclein function and dysfunction revealed its involvement in multiple normal and aberrant molecular processes and, consequently, numerous and diverse effects on the neuronal cell biology [...]
Externí odkaz:
https://doaj.org/article/6f2cac345cd94e4fabd80b6222b09d1c
Publikováno v:
Molecules, Vol 26, Iss 11, p 3078 (2021)
Recent studies have implicated synucleins in several reactions during the biosynthesis of lipids and fatty acids in addition to their recognised role in membrane lipid binding and synaptic functions. These are among aspects of decreased synuclein fun
Externí odkaz:
https://doaj.org/article/39454c56edaf4a6d979390defac52a68
Autor:
Patrick S. Hosford, Natalia Ninkina, Vladimir L. Buchman, Jeffrey C. Smith, Nephtali Marina, Shahriar SheikhBahaei
Publikováno v:
Brain Sciences, Vol 10, Iss 9, p 583 (2020)
Synuclein (α, β, and γ) proteins are highly expressed in presynaptic terminals, and significant data exist supporting their role in regulating neurotransmitter release. Targeting the gene encoding α-synuclein is the basis of many animal models of
Externí odkaz:
https://doaj.org/article/6ce6a6308b2c44c1bcccb101ee746cff
Autor:
Sergey O. Bachurin, Kirill D. Chaprov, T. A. Ivanova, Michail S. Kukharsky, Alexander P. Rezvykh, Vladimir L. Buchman, Ekaterina A. Lysikova, Sergei Funikov, Alexei V. Deykin, Natalia Ninkina, Alexey Yu. Aksinenko
Publikováno v:
CNS Neuroscience & Therapeutics
Aims To assess effects of DF402, a bioisostere of Dimebon/Latrepirdine, on the disease progression in the transgenic model of amyotrophic lateral sclerosis (ALS) caused by expression of pathogenic truncated form of human FUS protein. Methods Mice rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4997d60d928480af1e9fe5a8f9afe3d
https://doi.org/10.1111/cns.13637
https://doi.org/10.1111/cns.13637
Autor:
Igor O. Kozlov, Dmitriy A. Serov, Evgeniya S. Seryogina, Maxim E. Astashev, Arina V. Tankanag, Kirill D. Chaprov, Ekaterina A. Lysikova, Natalia Ninkina, Evgeniy A. Zherebtsov, Andrey V. Dunaev
Publikováno v:
Optical Technologies for Biology and Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e9dd661b4348aac1521b99c35b980df
https://doi.org/10.1117/12.2626412
https://doi.org/10.1117/12.2626412
Autor:
R. K. Ovchinnikov, Andrey D. Durnev, Larisa G. Kolik, Kirill D. Chaprov, Natalia Ninkina, Michail S. Kukharsky, Aleksey A. Ustyugov, T. V. Tarasova, Andrei Yu. Roman, Vladimir L. Buchman
Publikováno v:
Neurobiology of Aging
The etiology and pathogenesis of Parkinson’s disease (PD) are tightly linked to the gain-of-function of α-synuclein. However, gradual accumulation of α-synuclein aggregates in dopaminergic neurons of substantia nigra pars compacta (SNpc) leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e042df9144efdfc3ec499d386485dc
https://doi.org/10.1016/j.neurobiolaging.2020.02.026
https://doi.org/10.1016/j.neurobiolaging.2020.02.026
Autor:
Owen M. Peters, Steven Millership, Tatyana A. Shelkovnikova, Ileana Soto, Lora Keeling, Anthony Hann, Nicholas Marsh-Armstrong, Vladimir L. Buchman, Natalia Ninkina
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 1, Pp 124-131 (2012)
Amyotrophic lateral sclerosis (ALS) is characterised by substantial loss of both upper and lower motor neuron function, with sensory and cognitive systems less affected. Though heritable forms of the disease have been described, the vast majority of
Externí odkaz:
https://doaj.org/article/32924db1ff434670bdb95f2f99cccca2
Autor:
Natalia Ninkina, Owen M. Peters, Natalie Connor-Robson, Kirill D. Chaprov, Holger B. Kramer, Dominic J. Withers, Arthur T. Kopylov, Vladimir L. Buchman, Steven Millership, Alex Montoya
Publikováno v:
The Journal of Biological Chemistry
Synucleins, a family of three proteins highly expressed in neurons, are predominantly known for the direct involvement of α-synuclein in the etiology and pathogenesis of Parkinson's and certain other neurodegenerative diseases, but their precise phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c25bdcdb04d42ed3e6e25fe31cef99
http://europepmc.org/articles/PMC8633583
http://europepmc.org/articles/PMC8633583
Autor:
Natalia Ninkina, Mikhail V. Pokrovskiy, Andrei Yu. Roman, Vladimir L. Buchman, Irina A. Guschina
Publikováno v:
Molecules
Volume 26
Issue 11
Molecules, Vol 26, Iss 3078, p 3078 (2021)
Volume 26
Issue 11
Molecules, Vol 26, Iss 3078, p 3078 (2021)
Background: Recent studies have implicated synucleins in several reactions during the biosynthesis of lipids and fatty acids in addition to their recognised role in membrane lipid binding and synaptic functions. All members of the synuclein family in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c0ba58a56eeb31beb60c84bb706ade