Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Natali Vasilevski"'
Autor:
Xianning Lai, Sarah Kit Leng Lui, Hiu Yan Lam, Yuta Adachi, Wen Jing Sim, Natali Vasilevski, Nicola J. Armstrong, Stephanie Claire Bridgeman, Nathan Michael Main, Tuan Zea Tan, Janina E. E. Tirnitz-Parker, Jean Paul Thiery, Hiromichi Ebi, Alan Prem Kumar, Pieter Johan Adam Eichhorn
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract Despite the promising antitumor activity of SHP2 inhibitors in RAS-dependent tumours, overall responses have been limited by their narrow therapeutic window. Like with all MAPK pathway inhibitors, this is likely the result of compensatory pa
Externí odkaz:
https://doaj.org/article/375510663f6147c1abe8dec01b58fcb1
Autor:
Pieter Johan Adam Eichhorn, Sarah Christine Elisabeth Wright, Violeta Serra, Jordi Rodon, Natali Vasilevski
Publikováno v:
Scientia
Cancers, Vol 13, Iss 1538, p 1538 (2021)
Cancers
Cancers, Vol 13, Iss 1538, p 1538 (2021)
Cancers
Simple Summary The phosphoinositide-3-kinase (PI3K) pathway is the most frequently activated pathway in human cancers. Consequently, a number of compounds targeting the various nodes of this pathway have been developed. However, the majority of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15474e65e2c98e082d3b71211c3196c8
https://hdl.handle.net/11351/7210
https://hdl.handle.net/11351/7210
Autor:
Giuseppe Verdile, Sarah Kit Leng Lui, Pieter Johan Adam Eichhorn, Anand D. Jeyasekharan, Patrick Jaynes, Prasanna Vasudevan Iyengar, Natali Vasilevski, Sarah Christine Elizabeth Wright, Tuan Zea Tan
Publikováno v:
Scientific Reports, 10(1). NATURE RESEARCH
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Systematic control of the transforming growth factor-β (TGFβ) pathway is essential to keep the amplitude and the intensity of downstream signalling at appropriate levels. Ubiquitination plays a crucial role in the general regulation of this pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d82409b9c40560b56a782e645e1a46c
https://www.nature.com/articles/s41598-020-72791-0
https://www.nature.com/articles/s41598-020-72791-0