Výsledky vyhledávání - "Natale R. Sciolino"

Akademický článek

Partial or Complete Loss of Norepinephrine Differentially Alters Contextual Fear and Catecholamine Release Dynamics in Hippocampal CA1

Autor: Leslie R. Wilson, Nicholas W. Plummer, Irina Y. Evsyukova, Daniela Patino, Casey L. Stewart, Kathleen G. Smith, Kathryn S. Konrad, Sydney A. Fry, Alex L. Deal, Victor W. Kilonzo, Sambit Panda, Natale R. Sciolino, Jesse D. Cushman, Patricia Jensen

Publikováno v: Biological Psychiatry Global Open Science, Vol 4, Iss 1, Pp 51-60 (2024)

Background: Contextual fear learning is heavily dependent on the hippocampus. Despite evidence that catecholamines contribute to contextual encoding and memory retrieval, the precise temporal dynamics of their release in the hippocampus during behavi

Externí odkaz: https://doaj.org/article/8050ff2fc93446f3a539787dd28c9b3e

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Akademický článek

Recombinase-Dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types

Autor: Natale R. Sciolino, Nicholas W. Plummer, Yu-Wei Chen, Georgia M. Alexander, Sabrina D. Robertson, Serena M. Dudek, Zoe A. McElligott, Patricia Jensen

Publikováno v: Cell Reports, Vol 15, Iss 11, Pp 2563-2573 (2016)

Chemogenetic technologies, including the mutated human Gq-coupled M3 muscarinic receptor (hM3Dq), have greatly facilitated our ability to directly link changes in cellular activity to altered physiology and behavior. Here, we extend the hM3Dq toolkit

Externí odkaz: https://doaj.org/article/382371775c1747b69ca902a58db2cb89

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Partial or complete loss of norepinephrine differentially alters contextual fear and catecholamine release dynamics in hippocampal CA1

Autor: Leslie R. Wilson, Nicholas W. Plummer, Irina Y. Evsyukova, Daniela Patino, Casey L. Stewart, Kathleen G. Smith, Sydney A Fry, Alex L. Deal, Victor W. Kilonzo, Natale R. Sciolino, Jesse D. Cushman, Patricia Jensen

Contextual fear learning is heavily dependent on the hippocampus. Despite evidence that catecholamines contribute to contextual encoding and memory retrieval, the precise temporal dynamics of their release in the hippocampus during behavior is unknow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7421c20c7aae23bac7b796cdd868d48
https://doi.org/10.1101/2023.03.26.534277

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Natural locus coeruleus dynamics during feeding

Autor: Natale R. Sciolino, Madeline Hsiang, Christopher M. Mazzone, Leslie R. Wilson, Nicholas W. Plummer, Jaisal Amin, Kathleen G. Smith, Christopher A. McGee, Sydney A. Fry, Cindy X. Yang, Jeanne M. Powell, Michael R. Bruchas, Alexxai V. Kravitz, Jesse D. Cushman, Michael J. Krashes, Guohong Cui, Patricia Jensen

Publikováno v: Science Advances. 8

Recent data demonstrate that noradrenergic neurons of the locus coeruleus (LC-NE) are required for fear-induced suppression of feeding, but the role of endogenous LC-NE activity in natural, homeostatic feeding remains unclear. Here, we found that LC-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea155009c174ef50d83669c7db29e73
https://doi.org/10.1126/sciadv.abn9134

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Chemogenetic stimulation of tonic locus coeruleus activity strengthens the default mode network

Autor: Weiting Zhang, Esteban A. Oyarzabal, Sheng Song, Sung-Ho Lee, Irina Evsyukova, Natale R. Sciolino, Patricia Jensen, Yen-Yu Ian Shih, Hong Yuan, Manasmita Das, Kathleen G. Smith, Tzu-Hao Harry Chao, Guohong Cui, Jingheng Zhou, Li-Ming Hsu

Publikováno v: Science advances. 8(17)

The default mode network (DMN) of the brain is involved in cognition, emotion regulation, impulsivity, and balancing between internally and externally focused states. DMN dysregulation has been implicated in several neurological and neuropsychiatric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e7e33707e601efacd037ebcd6e3350
https://pubmed.ncbi.nlm.nih.gov/35486721

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A role for the locus coeruleus in the modulation of feeding

Recent data suggest that LC-NE neurons play a role in fear-induced suppression of feeding, but their endogenous activity in naturally behaving animals has not been explored. We found that endogenous activity of LC-NE neurons was enhanced during food

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873e7b79908ef3118f43d01214a6a5cc

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Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviors

Autor: Natale R. Sciolino, Patricia Jensen, Jeanne M. Powell, David Weinshenker, Daniel Lustberg, L. Cameron Liles, Madeline Hsiang, Rachel P Tillage, Kathleen G. Smith, Nicholas W. Plummer

Publikováno v: Brain Struct Funct

Accumulating evidence indicates that disruption of galanin signaling is associated with neuropsychiatric disease, but the precise functions of this neuropeptide remain largely unresolved due to lack of tools for experimentally disrupting its transmis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebf566ab7cdd3bdb83cd172992122ae
https://pubmed.ncbi.nlm.nih.gov/32065256

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The galanin receptor agonist, galnon, attenuates cocaine-induced reinstatement and dopamine overflow in the frontal cortex

Autor: Natale R. Sciolino, Philip V. Holmes, Gaylen L. Edwards, Jessica L. Groves-Chapman, Jason P. Schroeder, Yvonne E. Ogbonmwan, Kimberly G. Freeman, David Weinshenker

Publikováno v: Addiction Biology. 20:701-713

Relapse represents one of the most significant problems in the long-term treatment of drug addiction. Cocaine blocks plasma membrane monoamine transporters and increases dopamine (DA) overflow in the brain, and DA is critical for the motivational and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a89144b2bfa7bdf3a1348558f93cdef
https://doi.org/10.1111/adb.12166

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