Comprehensive structural investigation of a potent and selective CXCR4 antagonist via crosslink modification

Autor: Trotta, Anna Maria, Mazzarella, Vincenzo, Roggia, Michele, D'Aniello, Antonia, Del Bene, Alessandra, Vetrei, Cinzia, Di Maiolo, Gaetana, Campagna, Erica, Natale, Benito, Rea, Giuseppina, Santagata, Sara, D'Alterio, Crescenzo, Cutolo, Roberto, Mottola, Salvatore, Merlino, Francesco, Benedetti, Rosaria, Altucci, Lucia, Messere, Anna, Cosconati, Sandro, Tomassi, Stefano, Scala, Stefania, Di Maro, Salvatore

Publikováno v: In European Journal of Medicinal Chemistry 5 December 2024 279

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Identification of Dual Inhibitors Targeting Main Protease (M^pro) and Cathepsin L as Potential Anti-SARS-CoV‑2 Agents.

Autor: Previti, Santo, Ettari, Roberta, Calcaterra, Elsa, Roggia, Michele, Natale, Benito, Weldert, Annabelle C., Müller-Ruttloff, Christin, Salisch, Florian, Irto, Anna, Cigala, Rosalia Maria, Ziebuhr, John, Schirmeister, Tanja, Cosconati, Sandro, Zappalà, Maria

Publikováno v: ACS Medicinal Chemistry Letters; 5/9/2024, Vol. 15 Issue 5, p602-609, 8p

Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity.

Autor: Poggetti V; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Angeloni E; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Germelli L; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Natale B; DiSTABiF, University of Campania Luigi Vanvitelli, Via Vivaldi, 43, 81100 Caserta, Italy., Waqas M; DiSTABiF, University of Campania Luigi Vanvitelli, Via Vivaldi, 43, 81100 Caserta, Italy., Sarno G; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, SA, Italy., Angeli A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, Polo Scientifico, University of Florence, Via U. Schiff, 6, Sesto Fiorentino, 50019 Firenze, Italy., Daniele S; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Salerno S; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Barresi E; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Cosconati S; DiSTABiF, University of Campania Luigi Vanvitelli, Via Vivaldi, 43, 81100 Caserta, Italy., Castellano S; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, SA, Italy., Da Pozzo E; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Costa B; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, Polo Scientifico, University of Florence, Via U. Schiff, 6, Sesto Fiorentino, 50019 Firenze, Italy., Da Settimo F; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy., Taliani S; Department of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2024 Nov 15. Date of Electronic Publication: 2024 Nov 15.