Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Natacha Prevost"'
Publikováno v:
The Journal of Organic Chemistry
A strategy for the synthesis of the lycopodium alkaloid dihydrolycolucine (1) has been investigated. Synthetic routes were developed based on N-acylpyridinium salt chemistry to prepare target fragments 3 and 4 that could ultimately converge to the na
Autor:
Jerome F. Hayes, Michael Shipman, Sabitur Rahman, Gildas Prie, Natacha Prevost, Cyril Montagne, Jason J. Shiers
Publikováno v:
Tetrahedron. 62:8447-8457
2-Methyleneaziridinyl anions can be produced by selective deprotonation of the parent aziridine at C-3 using sec-BuLi/TMEDA. Subsequent reaction with a wide variety of electrophiles including MeI, ICH2CH2CH2CH2Cl, PhCH2Br, allyl bromide, Me3SiCl, Bu3
Autor:
Michael Shipman, Jerome F. Hayes, Gildas Prie, Natacha Prevost, Stephanie A. Fernandes, Heather Twin
Publikováno v:
Angewandte Chemie. 116:6679-6681
Autor:
Stephan Georg Mueller, Anna Pedret-Dunn, Natacha Prevost, Clemens Moeller, Christopher Brown, Juergen Prestle, Bernd Nosse, Stefan Scheuerer, Marcus Schindler, Mark Whittaker, Alexander Heifetz, Heather Tye
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(1)
The discovery of a novel series of 5-HT2C agonists based on a tricyclic pyrazolopyrimidine scaffold is described. Compounds with good levels of in vitro potency and moderate to good levels of selectivity with respect to the 5-HT2A and 5-HT2B receptor
Autor:
Michael Shipman, Natacha Prevost
Publikováno v:
ChemInform. 32
Autor:
Natacha Prevost, Michael Shipman
Publikováno v:
ChemInform. 34
Rearrangement of a variety of 3-(2-methyleneaziridin-1-yl)propyl radicals, generated using Bu 3 SnH/AIBN by homolytic cleavage of phenylselenide substituted 2-methyleneaziridines, produces 3-methylenepiperidines in yields ranging from 58 to 68%. By c
Autor:
Heather Twin, Alexandra M. Z. Slawin, Ivan Prokes, Michael Shipman, Jerome F. Hayes, Natacha Prevost
Publikováno v:
Scopus-Elsevier
Lithiation and alkylation of a 2-isopropylidineaziridine bearing an (S)-alpha-methylbenzyl group on nitrogen proceeds with high levels of diastereocontrol (80-90% de).
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1c1eda3de80f4a214d7802df4c9558
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http://www.scopus.com/inward/record.url?eid=2-s2.0-0038717316&partnerID=MN8TOARS