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pro vyhledávání: '"Natacha C.F. Santos"'
Autor:
Antonieta C. R. Alencastro, Rene Oliveira Beleboni, Marcelo Hermes-Lima, Carlos A. Navas, Natacha C.F. Santos
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 146:1-9
Although the number of science and engineering (SE) publications produced in Latin America grew exponentially over the past 15 years, the investment in science and the number of full time researchers did not grow at a comparable rate. Moreover, Latin
Publikováno v:
IUBMB life. 59(4-5)
Summary Science in Latin America has experienced vigorous growth in the past decade, as demonstrated by the fact that the Latin American share of the world’s scientific publications increased from 1.8% in 1991 – 1995 to 3.4% in 1999 – 2003. Sig
Publikováno v:
European journal of pharmacology. 428(1)
Pyridoxal isonicotinoyl hydrazone (PIH) is able to prevent iron-mediated hydroxyl radical formation by means of iron chelation and inhibition of redox cycling of the metal. In this study, we investigated the effect of PIH on Fe(II)-citrate-mediated l
Autor:
Natacha C.F. Santos, Herbert M. Schulman, Mark Andrews, Prem Ponka, Junguo Yan, Marcelo Hermes-Lima
Publikováno v:
Biochimica et biophysica acta. 1426(3)
The search for effective iron chelating agents was primarily driven by the need to treat iron-loading refractory anemias such as beta-thalassemia major. However, there is a potential for therapeutic use of iron chelators in non-iron overload conditio