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Stem cells have generated considerable interest recently in the scientific, clinical, and public arenas. The third book in the Stem Cell Repair and Regeneration series offers contributions from numerous areas bridging medicine and the life sciences.S
Stem cell research is one of the leading “cutting edge” areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by
This second book in the Stem Cell Repair and Regeneration series provides a deeper exploration of the therapeutic potential of undifferentiated human stem cells.Regenerative medicine is an extremely fast-moving field which is evolving from the initia
Publikováno v:
Regenerative Medicine. 7:387-395
Worldwide, tissue engineering and cellular replacement therapies are at the forefront of the regenerative medicine agenda, and researchers are addressing key diseases, including diabetes, stroke and neurological disorders. It is becoming evident that
Autor:
Salah Helmy, Long R. Jiao, Christos Rountas, Paul Tait, Michael S. Scott, Nataša Levičar, Miroslav Milicevic, Shahid A. Khan, Despina Kyriakou, Dimitris Zacharoulis, Stephen B. Marley, Nagy A. Habib, Madhava Pai, Andrew V. Thillainayagam, Joanna Nicholls, Kevin Jestice, Myrtle Y. Gordon, Devinder S. Bansi, Maria Glibetic, Jane F. Apperley, Steen Lindkaer Jensen
Publikováno v:
The American Journal of Gastroenterology. 103:1952-1958
Recent advances in regenerative medicine, including hematopoietic stem cell (HSC) transplantation, have brought hope for patients with severe alcoholic liver cirrhosis (ALC). The aim of this study was to assess the safety and efficacy of administerin
Autor:
Joanna Nicholls, J. F. Apperley, Paul Tait, Long R. Jiao, Nataša Levičar, C. Smadja, John C. Davis, Francesco Dazzi, Nagy A. Habib, S. B. Marley, Madhava Pai, Myrtle Y. Gordon, Steen Lindkaer Jensen
Publikováno v:
Cell Proliferation. 41:115-125
Evidence is growing in support of the role of stem cells as an attractive alternative in treatment of liver diseases. Recently, we have demonstrated the feasibility and safety of infusing CD34(+) adult stem cells; this was performed on five patients
Publikováno v:
Journal of Cardiothoracic-Renal Research. 1:107-114
Summary Recent developments in the field of regenerative stem cell therapy for ischaemic heart disease have lead to an explosion in the clinical trial realm. At present no consensus exists regarding, amongst others, the optimal cell type as well as t
Autor:
Federica M. Marelli-Berg, Francesco Dazzi, Stephen B. Marley, Paul Tait, Rikke Dodge, Steen Lindkaer Jensen, Nataša Levičar, Madhava Pai, Myrtle Y. Gordon, Ahmet Ayav, Malcolm Alison, Mahrokh Nohandani, Philippe Bachellier, Raymond J. Playford, Joanna Nicholls, Tamara Thalji, Faisal A. Al-Allaf, Nagy A. Habib, John Davies, Hanane M’Hamdi, Robert I. Lechler, Farzin Farzaneh, Joop Gaken, Jane F. Apperley, Long R. Jiao, Ioannis Dimarakis, Jonathan P. Welsh
Publikováno v:
STEM CELLS. 24:1822-1830
A phase I study was performed to determine the safety and tolerability of injecting autologous CD34(+) cells into five patients with liver insufficiency. The study was based on the hypothesis that the CD34(+) cell population in granulocyte colony-sti
Autor:
Tamara T. Lah, Ricardo A Dewey, Emma Daley, Nataša Levičar, Derek Davies, Janko Kos, Timothy E. Bates, Geoffrey J. Pilkington
Publikováno v:
Cancer Gene Therapy. 10:141-151
Invasion and metastasis of certain tumors are accompanied by increased mRNA protein levels and enzymatic activity of cathepsin L. Cathepsin L has also been suggested to play a role in the proteolytic cascades associated with apoptosis. To investigate
Autor:
Nataša Levičar, Tadej Strojnik, Janko Kos, Geoffrey J. Pilkington, Tamara T. Lah, Ricardo A Dewey
Publikováno v:
Journal of Neuro-Oncology. 58:21-32
The expression patterns of different classes of peptidases in central nervous system (CNS) tumours have been most extensively studied in astrocytomas and meningiomas. Although the two types of tumours are very different in most respects, both may inv