Výsledky vyhledávání - "Nataša Lekić"

The involvement of heme oxygenase 1 but not nitric oxide synthase 2 in a hepatoprotective action of quercetin in lipopolysaccharide-induced hepatotoxicity of d-galactosamine sensitized rats

Autor: Hassan Farghali, Nataša Lekić, Nikolina Kutinová Canová, Aleš Hořínek

Publikováno v: Fitoterapia. 87:20-26

The objective of this study was to evaluate potential hepatoprotective capabilities of quercetin in relation to its modulation of the HO-1 and NOS-2 activities in an experimental model of fulminant liver failure. Liver insult was induced by in vivo a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f520fb60da2b23405a77df1b53874a
https://doi.org/10.1016/j.fitote.2013.03.016

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Resveratrol and related compounds as antioxidants with an allosteric mechanism of action in epigenetic drug targets

Autor: Nataša Lekić, H Farghali, N Kutinová Canová

Publikováno v: Scopus-Elsevier
ResearcherID

The present review is intended to focus on naturally occurring cytoprotective agents such as resveratrol (trans-3,4’,5-trihydroxystilbene) and other related compounds, probably with similar molecular mechanisms of action and high capacity to find a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfd8efa03b5b76aec20be6622212182
https://pubmed.ncbi.nlm.nih.gov/23173686

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Hepatoprotective effect of curcumin in lipopolysaccharide/-galactosamine model of liver injury in rats: relationship to HO-1/CO antioxidant system

Autor: Nataša Lekić, Zdeněk Zídek, Kameníková L, Lucie Muchová, Aleš Hořínek, Kateřina Váňová, Hassan Farghali, Dalibor Černý, Eva Kmoníčková

Publikováno v: Fitoterapia. 82(5)

This work studied a relationship between HO-1/CO system and lipid peroxidation with consequent effects on liver functions and NOS-2. We focused on curcumin pretreatment in rat toxic model of d-galactosamine and lipopolysaccharide. Hepatocyte viabilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b2695ce994d6cedb440f4d1b1194fd
https://pubmed.ncbi.nlm.nih.gov/21545828

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Heme oxygenase 1/carbon monoxide and nitric oxide synthase 2/nitric oxide systems in cytotoxicity and cytoprotection: Application to experimental liver research

Autor: Nataša Lekić, Hassan Farghali, Dalibor Černý, Kameníková L

Publikováno v: Toxicology Letters. 205:S182

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ae4f251ffa3a9cef9c82dde1691765e
https://doi.org/10.1016/j.toxlet.2011.05.633

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Differential Oxidative Stress Responses to D-Galactosamine-Lipopolysaccharide Hepatotoxicity Based on Real Time PCR Analysis of Selected Oxidant/Antioxidant and Apoptotic Gene Expressions in Rat

Autor: Aleš Hořínek, Dalibor Černý, Zdeněk Provazník, Hassan Farghali, Nataša Lekić, J Martínek

Publikováno v: ResearcherID
Scopus-Elsevier
Europe PubMed Central

Oxidative stress and apoptosis are proposed mechanisms of cellular injury in studies of xenobiotic hepatotoxicity. This study is focused on addressing the mutual relationship and early signals of these mechanisms in the D-galactosamine and lipopolysa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70eb086d68fc9ccc1a0f8f668f7c821e
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000293138600016&KeyUID=WOS:000293138600016

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