Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Natália Teruel"'
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1009286 (2021)
The SARS-CoV-2 Spike protein needs to be in an open-state conformation to interact with ACE2 to initiate viral entry. We utilise coarse-grained normal mode analysis to model the dynamics of Spike and calculate transition probabilities between states
Externí odkaz:
https://doaj.org/article/8d83078b6d3d4c518b26ee6537a0c4cb
Computational methods for the quantification and visualization of the relative contribution of molecular interactions to the stability of biomolecular structures and complexes are fundamental to understand, modulate and engineer biological processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709c586cebfcd055c0a736dcdd95c300
https://doi.org/10.1101/2023.04.26.538470
https://doi.org/10.1101/2023.04.26.538470
Publikováno v:
Bioinformatics (Oxford, England). 38(15)
Summary We present Systematic ProtEin AnnotatoR (SPEAR), a lightweight and rapid SARS-CoV-2 variant annotation and scoring tool, for identifying mutations contributing to potential immune escape and transmissibility (ACE2 binding) at point of sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc3463ae5ffae88feea471aaa7a4f5d
https://pubmed.ncbi.nlm.nih.gov/35695776
https://pubmed.ncbi.nlm.nih.gov/35695776
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1009286 (2021)
PLoS Computational Biology
PLoS Computational Biology
The SARS-CoV-2 Spike protein needs to be in an open-state conformation to interact with ACE2 to initiate viral entry. We utilise coarse-grained normal mode analysis to model the dynamics of Spike and calculate transition probabilities between states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4229a9d4ba36774695c20ab1dcadf07
https://doi.org/10.1371/journal.pcbi.1009286
https://doi.org/10.1371/journal.pcbi.1009286
Autor:
Carlos A Rodríguez-Salazar, Sarah van Tol, Olivier Mailhot, Maria Gonzalez-Orozco, Gabriel T Galdino, Abbey N Warren, Natalia Teruel, Padmanava Behera, Kazi Sabrina Afreen, Lihong Zhang, Terry L Juelich, Jennifer K Smith, María Inés Zylber, Alexander N Freiberg, Rafael J Najmanovich, Maria I Giraldo, Ricardo Rajsbaum
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002544 (2024)
Ebolavirus (EBOV) belongs to a family of highly pathogenic viruses that cause severe hemorrhagic fever in humans. EBOV replication requires the activity of the viral polymerase complex, which includes the cofactor and Interferon antagonist VP35. We p
Externí odkaz:
https://doaj.org/article/99a4e0e8910746299e1402b8c51819c3