Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Natália G. Sampaio"'
Autor:
Xavier Sisquella, Yifat Ofir-Birin, Matthew A. Pimentel, Lesley Cheng, Paula Abou Karam, Natália G. Sampaio, Jocelyn Sietsma Penington, Dympna Connolly, Tal Giladi, Benjamin J. Scicluna, Robyn A. Sharples, Andreea Waltmann, Dror Avni, Eli Schwartz, Louis Schofield, Ziv Porat, Diana S. Hansen, Anthony T. Papenfuss, Emily M. Eriksson, Motti Gerlic, Andrew F. Hill, Andrew G. Bowie, Neta Regev-Rudzki
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
STING is an intracellular DNA sensor that can alter response to infection, but in the case of malaria it is unclear how parasite DNA in red blood cells (RBCs) reaches DNA sensors in immune cells. Here the authors show that STING in human monocytes ca
Externí odkaz:
https://doaj.org/article/144b9d639c34432f83aff80548d8d525
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/085a17c9de9e4b4e85f77980d484ec0b
Autor:
Sarah Straub, Natalia G. Sampaio
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Early detection of infection is a central and critical component of our innate immune system. Mammalian cells have developed specialized receptors that detect RNA with unusual structures or of foreign origin – a hallmark of many virus infections. A
Externí odkaz:
https://doaj.org/article/a7fc77d292704ad3b1b1d4a1da4a1e25
Autor:
Natalia G. Sampaio, Lise Chauveau, Jonny Hertzog, Anne Bridgeman, Gerissa Fowler, Jurgen P. Moonen, Maeva Dupont, Rebecca A. Russell, Marko Noerenberg, Jan Rehwinkel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Human cells respond to infection by SARS-CoV-2, the virus that causes COVID-19, by producing cytokines including type I and III interferons (IFNs) and proinflammatory factors such as IL6 and TNF. IFNs can limit SARS-CoV-2 replication but cyt
Externí odkaz:
https://doaj.org/article/bf7b2861bd4e49ec90699e30b9ce5848
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202408 (2018)
Toll like receptors (TLRs) are important pattern recognition receptors that can detect pathogen and danger associated molecular patterns to initiate an innate immune response. TLR1 and 2 heterodimerize at the plasma membrane upon binding to triacylat
Externí odkaz:
https://doaj.org/article/a0e0618a92624bf9b0b0550edefe4b44