Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Natália Fontana Nicoletti"'
Publikováno v:
Journal of Biosciences and Medicines. :15-29
Objective: To describe the relationship between autophagy and apoptosis and the possible signaling pathways involved in degenerative lumbar intervertebral disc. Summary of Background Data: Autophagy and apoptosis are regulatory cellular mechanisms th
Autor:
Manuela Peletti-Figueiró, Natália Fontana Nicoletti, Asdrubal Falavigna, Anderson Ricardo Ingracio, Fernanda Trindade Gonzalez Dias, Otávio Bianchi
Publikováno v:
Journal of Biosciences and Medicines. :26-42
Modulating healing factors could avoid or minimize some possible pathological processes in collagen deposition. The present study was aimed to evaluated the role of active biomolecules such as PDGF-BB and PRP loaded or not into polymeric biomaterial
Autor:
Asdrubal Falavigna, Bruno Saciloto, Manuela Figueiró, Natália Fontana Nicoletti, Charles A Carazzo
Publikováno v:
Journal of Biosciences and Medicines. :68-77
Objective: To characterize the association between DNA damage and Intervertebral disc degeneration (IDD). Summary of Background Data: IDD is the main disorder causing low back pain and is the most promising target for intervention. Many factors can c
Autor:
Natália Fontana Nicoletti, Daniel Rodrigo Marinowic, Fernanda Trindade Gonzalez Dias, Lucas Dall Agnol, Sidnei Moura E Silva, Asdrubal Falavigna, Ángel Marcos-Fernández, Otávio Bianchi
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The microdiscectomy used for the treatment of intervertebral disc disorders leaves an open incision in the annulus fibrosus that must be sealed to avoid re-herniation and other subsequent degenerations. In this study, we developed an injectable and i
Autor:
Giovanna Ramos Garcez, Natália Fontana Nicoletti, Ricardo Meurer Papaléo, Jefferson Braga Silva, Nara Regina de Souza Basso, Pedro Cesar Chagastelles, Bruna Sgarioni, Cristhiane Alvim Valente, Fábio Herrmann, Maria M. Campos, Mara Lise Zanini, Gustavo Guthmann Pesenatto, Eduardo Goldani
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:1522-1534
This study investigated the effects of smooth and microgrooved membrane blends, with different polycaprolactone (PCL)/ poly(lactic-co-glycolic acid) (PLGA) ratios on the viability, proliferation, and adhesion of different mammalian cell types. The po
Autor:
Thaís Cristina Erig, Marcus Vinicius Gomez, Natália Fontana Nicoletti, Nelson Pires Ferreira, Maria M. Campos, Marcelo Ricardo Roxo, Rafael Fernandes Zanin, Fernanda Bueno Morrone
Publikováno v:
Toxicon. 129:58-67
This study investigated the effects of P/Q- and N-type voltage-gated calcium channel (VGCC) blockers derived from P. nigriventer in glioma progression, by means of in vitro and in vivo experiments. Glioma cells M059J, U-138MG and U-251MG were used to
Autor:
Vinicius Duval da Silva, Natália Fontana Nicoletti, Nelson Pires Ferreira, Maria M. Campos, Jacques Sénécal, Réjean Couture, Fernanda Bueno Morrone, Marcelo Ricardo Roxo, João Bosco Pesquero, Rafael Leite Morais
Publikováno v:
Molecular Neurobiology. 54:7869-7882
This study investigated the role of kinins and their receptors in malignant brain tumors. As a first approach, GL-261 glioma cells were injected (2 × 105 cells in 2 μl/2 min) into the right striatum of adult C57/BL6 wild-type, kinin B1 and B2 recep
Autor:
Rafael Roesler, Fernanda Bueno Morrone, Natália Fontana Nicoletti, Aroldo Braga Filho, Guido Lenz, Maria M. Campos, Alessandra Sayuri Kikuchi Tamajusuku, Marina P. Gehring, Franciele Cristina Kipper, Rafael Fernandes Zanin, Nathalia D. M. Sperotto, Luise Meurer, Debora Gazzana Flores
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 68:92-100
Glioblastoma multiforme (GBM) is considered the most lethal intracranial tumor and the median survival time is approximately 14 months. Although some glioma cells present radioresistance, radiotherapy has been the mainstay of therapy for patients wit
Autor:
Otávio Bianchi, Jaderson Costa da Costa, Anderson Ricardo Ingracio, Natália Fontana Nicoletti, Fernanda Trindade Gonzalez Dias, Felipe Castro Menezes, Asdrubal Falavigna, Rosane Michele Duarte Soares, Daniel Rodrigo Marinowic, Lucas Dall Agnol
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 99
Engineered skin coverings have been adopted clinically to support extensive and deep wounds that result in fewer healthy skin remaining and therefore take longer to heal. Nonetheless, these biomaterials demand intensive labor and an expensive final c
Autor:
Cristhiane, Alvim Valente, Pedro, Cesar Chagastelles, Natália, Fontana Nicoletti, Giovanna, Ramos Garcez, Bruna, Sgarioni, Fábio, Herrmann, Gustavo, Pesenatto, Eduardo, Goldani, Mara Lise, Zanini, Maria Martha, Campos, Ricardo, Meurer Papaléo, Jefferson, Braga da Silva, Nara Regina, de Souza Basso
Publikováno v:
Journal of biomedical materials research. Part A. 106(6)
This study investigated the effects of smooth and microgrooved membrane blends, with different polycaprolactone (PCL)/ poly(lactic-co-glycolic acid) (PLGA) ratios on the viability, proliferation, and adhesion of different mammalian cell types. The po