Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Natália Ferreira de Sousa"'
Autor:
Natália Ferreira de Sousa, Gabrielly Diniz Duarte, Carolina Borsoi Moraes, Cecília Gomes Barbosa, Holli-Joi Martin, Nail N. Muratov, Yuri Mangueira do Nascimento, Luciana Scotti, Lúcio Holanda Gondim de Freitas-Júnior, José Maria Barbosa Filho, Marcus Tullius Scotti
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 912 (2024)
In 2019, the emergence of the seventh known coronavirus to cause severe illness in humans triggered a global effort towards the development of new drugs and vaccines for the SARS-CoV-2 virus. These efforts are still ongoing in 2024, including the pre
Externí odkaz:
https://doaj.org/article/291d71d6f69f4c8c9fca576dbc687759
Autor:
Rafael Carlos Ferreira, Sâmia Sousa Duarte, Valgrícia Matias de Sousa, Ramon Ramos Marques de Souza, Karinne Kelly Gadelha Marques, Renata Albuquerque de Abrantes, Yuri Mangueira do Nascimento, Natália Ferreira de Sousa, Marcus Tullius Scotti, Luciana Scotti, Josean Fechine Tavares, Juan Carlos Ramos Gonçalves, Marcelo Sobral da Silva, Marianna Vieira Sobral
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1553 (2023)
The characterization and cytotoxicity of the essential oil from Conyza bonariensis (L.) aerial parts (CBEO) were previously conducted. The major compound was (Z)-2-lachnophyllum ester (EZ), and CBEO exhibited significant ROS-dependent cytotoxicity in
Externí odkaz:
https://doaj.org/article/17fc57ea2e7f4e27bfa0afd8002f4d97
Methyleugenol Has an Antidepressant Effect in a Neuroendocrine Model: In Silico and In Vivo Evidence
Autor:
Mayara Cecile Nascimento Oliveira, Ikla Lima Cavalcante, Alana Natalícia de Araújo, Aline Matilde Ferreira dos Santos, Renata Priscila Barros de Menezes, Chonny Herrera-Acevedo, Natália Ferreira de Sousa, Jailane de Souza Aquino, José Maria Barbosa-Filho, Ricardo Dias de Castro, Reinaldo Nóbrega Almeida, Luciana Scotti, Marcus Tullius Scotti, Mirian Graciela Da Silva Stiebbe Salvadori
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1408 (2023)
Major depressive disorder is a severe mood disorder characterized by different emotions and feelings. This study investigated the antidepressant activity of the phenylpropanoid methyleugenol (ME) in adult female mice exposed to a stress model induced
Externí odkaz:
https://doaj.org/article/ba1b02714ade488ab55c6e8bc7971b66
Autor:
Fernando Ferreira Leite, Natália Ferreira de Sousa, Bruno Hanrry Melo de Oliveira, Gabrielly Diniz Duarte, Maria Denise Leite Ferreira, Marcus Tullius Scotti, José Maria Barbosa Filho, Luís Cezar Rodrigues, Ricardo Olímpio de Moura, Francisco Jaime Bezerra Mendonça-Junior, Luciana Scotti
Publikováno v:
Molecules, Vol 28, Iss 10, p 4009 (2023)
Chalcones are direct precursors in the biosynthesis of flavonoids. They have an α,β-unsaturated carbonyl system which gives them broad biological properties. Among the biological properties exerted by chalcones, their ability to suppress tumors sta
Externí odkaz:
https://doaj.org/article/2c40d4b3f62f4fa892460eb9eb7f26bd
Autor:
Chonny Herrera-Acevedo, Renata Priscila Barros de Menezes, Natália Ferreira de Sousa, Luciana Scotti, Marcus Tullius Scotti, Ericsson Coy-Barrera
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 663 (2023)
The bifunctional enzyme Dihydrofolate reductase-thymidylate synthase (DHFR-TS) plays a crucial role in the survival of the Leishmania parasite, as folates are essential cofactors for purine and pyrimidine nucleotide biosynthesis. However, DHFR inhibi
Externí odkaz:
https://doaj.org/article/e0384673a6e743debcf6c61aedbcccec
Autor:
Natália Ferreira de Sousa, Helivaldo Diógenes da Silva Souza, Renata Priscila Barros de Menezes, Francinara da Silva Alves, Chonny Alexander Herrera Acevedo, Thaís Amanda de Lima Nunes, Zoe L. Sessions, Luciana Scotti, Eugene N. Muratov, Francisco Jaime Bezerra Mendonça-Junior, Klinger Antônio da Franca Rodrigues, Petrônio Filgueiras de Athayde Filho, Marcus Tullius Scotti
Publikováno v:
Pathogens, Vol 12, Iss 1, p 136 (2023)
The World Health Organization classifies Leishmania as one of the 17 “neglected diseases” that burden tropical and sub-tropical climate regions with over half a million diagnosed cases each year. Despite this, currently available anti-leishmania
Externí odkaz:
https://doaj.org/article/5da8060d3b464d6ba8aa9938196cd177
Autor:
Débora Chaves Cajazeiro, Paula Pereira Marques Toledo, Natália Ferreira de Sousa, Marcus Tullius Scotti, Juliana Quero Reimão
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1634 (2022)
Toxoplasma gondii is a protozoan that infects up to a third of the world’s population. This parasite can cause serious problems, especially if a woman is infected during pregnancy, when toxoplasmosis can cause miscarriage, or serious complications
Externí odkaz:
https://doaj.org/article/838faec77fac4a638dab4e680054f9da
Autor:
Pablo Rayff da Silva, Renan Fernandes do Espírito Santo, Camila de Oliveira Melo, Fábio Emanuel Pachú Cavalcante, Thássia Borges Costa, Yasmim Vilarim Barbosa, Yvnni M. S. de Medeiros e Silva, Natália Ferreira de Sousa, Cristiane Flora Villarreal, Ricardo Olímpio de Moura, Vanda Lucia dos Santos
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 188 (2022)
The compound (E)-2-cyano-N,3-diphenylacrylamide (JMPR-01) was structurally developed using bioisosteric modifications of a hybrid prototype as formed from fragments of indomethacin and paracetamol. Initially, in vitro assays were performed to determi
Externí odkaz:
https://doaj.org/article/85db4375e4404b08839ab18499a6d0a8
Autor:
Gabriela Cristina Soares Rodrigues, Mayara dos Santos Maia, Andreza Barbosa Silva Cavalcanti, Natália Ferreira de Sousa, Marcus Tullius Scotti, Luciana Scotti
Publikováno v:
Molecules, Vol 26, Iss 3, p 766 (2021)
Background: The growing demand for agricultural products has led to the misuse/overuse of insecticides; resulting in the use of higher concentrations and the need for ever more toxic products. Ecologically, bioinsecticides are considered better and s
Externí odkaz:
https://doaj.org/article/1cd986dbd11545fe9860b228dbf48535
Autor:
Luciana Scotti, Pablo Rayff da Silva, Jéssica Cabral de Andrade, Natália Ferreira de Sousa, Anne Caroline Ribeiro Portela, Hugo Fernandes Oliveira Pires, Maria Caroline Rodrigues Bezerra Remígio, Danielle da Nóbrega Alves, Humberto Hugo Nunes de Andrade, Arthur Lins Dias, Mirian Graciela da Silva Stiebbe Salvadori, Adriana Maria Fernandes de Oliveira Golzio, Ricardo Dias de Castro, Marcus T. Scotti, Cícero Francisco Bezerra Felipe, Reinaldo Nóbrega de Almeida
Publikováno v:
Current Neuropharmacology. 21:842-866
Abstract: Alzheimer's and Parkinson's are neurodegenerative disorders that affect a great number of people around the world, seriously compromising the quality of life of individuals, due to motor and cognitive damage. In these diseases, pharmacologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e3777989d6ff89ff3d7d19327fd331
https://doi.org/10.2174/1570159x21666230221123059
https://doi.org/10.2174/1570159x21666230221123059