Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Natália Aparecida Nepomuceno"'
Autor:
Lucas Matos Fernandes, Alessandro Wasum Mariani, Israel Lopes de Medeiros, Marcos Naoyuki Samano, Luís Gustavo Abdalla, Aristides Tadeu Correia, Natália Aparecida Nepomuceno, Mauro Canzian, Paulo Manuel Pêgo-Fernandes
Publikováno v:
Acta Cirúrgica Brasileira, Vol 30, Iss 5, Pp 359-365 (2015)
PURPOSE: To evaluate a new perfusate solution to be used for ex vivo lung perfusion.METHODS: Randomized experimental study using lungs from rejected brain-dead donors harvested and submitted to 1 hour of ex vivo lung perfusion (EVLP) using mainstream
Externí odkaz:
https://doaj.org/article/e582699141d84bafb3e0c52eca9a2075
Autor:
Paolo Oliveira-Melo, Natalia Aparecida Nepomuceno, Liliane Moreira Ruiz, Aristides Tadeu Correia, Vanessa Sana Vilela, Karina Andrighetti de Oliveira Braga, Giovana Maria Manzuti, Deymisson Damitene Martins Feitosa, Emanuel Kennedy-Feitosa, Aizhou Wang, Marcelo Cypel, Paulo Manuel Pêgo Fernandes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Brain death (BD) provides most of the donor organs destined for lung transplantation (LTx). However, the organs may be affected by inflammatory and oxidative processes. Based on this, we hypothesize that the angiotensin-converting enzyme 2 (
Externí odkaz:
https://doaj.org/article/6a6ffc43bb4141b2993b52aeba8684f5
Autor:
Isaac de Faria Soares Rodrigues, Paulo Francisco Guerreiro Cardoso, Natalia Aparecida Nepomuceno da Silva, Aristides Tadeu Correia, Helio Minamoto, Benoit Jacques Bibas, Natalia de Souza Xavier Costa, Marilia Wellichan Mancini, Marisa Dolhnikoff, Paulo Manuel Pego-Fernandes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract To compare two different wavelengths of the surgical contact diode laser (CDL) for producing a posterior laryngofissure in in-vivo pigs. Anesthetized pigs underwent a tracheostomy and an anterior laryngofissure through a cervicotomy. They we
Externí odkaz:
https://doaj.org/article/819c6ebbfed64dd4a29e5febb62e9d9a
Autor:
Vanessa Sana Vilela, Karina Andrighetti de Oliveira Braga, Liliane Moreira Ruiz, Natalia Aparecida Nepomuceno, Paolo Oliveira Melo, Giovana Maria Manzuti, Vinícius Alcantara de Oliveira Costa, Jhonatan de Campos Ramos, Aristides Tadeu Correia, Paulo Manuel Pêgo-Fernandes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Lung transplantation stands as a vital treatment for severe lung diseases, primarily sourcing organs from donors with brain death (BD). This research delved into the potential anti-inflammatory effects of thalidomide in rats with BD-induced
Externí odkaz:
https://doaj.org/article/034fc8332ef04ed19ceb4e19efe8052b
Autor:
Alexandre Chagas Santana, Wellington Andraus, Dan Zimelewicz Oberman, Nícollas Nunes Rabelo, Filipe Miranda Oliveira Silva, Humberto Dellê, Rafael Pepineli, Edvaldo Leal de Moraes, Cristoforo Scavone, Larissa de Sá Lima, Sabrina Degaspari, Sérgio Brasil, Davi Jorge Fontoura Solla, Liliane Moreira Ruiz, Karina Andrighetti de Oliveira-Braga, Natalia Aparecida Nepomuceno, Paulo Manuel Pêgo-Fernandes, Stefan Gunther Tullius, Eberval Gadelha Figueiredo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Liver transplantation has come a long way and is now regarded as the gold standard treatment for end-stage liver failure. The great majority of livers utilized in transplantation come from brain-dead donors. A broad inflammatory response cha
Externí odkaz:
https://doaj.org/article/75148395e7e1446d9d765d116d6e8d60
Autor:
Alexandre Chagas Santana, Wellington Andraus, Filipe Miranda Oliveira Silva, Humberto Dellê, Rafael Pepineli, Edvaldo Leal de Moraes, Cristoforo Scavone, Larissa de Sá Lima, Sabrina Degaspari, Sergio Brasil, Davi Jorge Fontoura Solla, Liliane Moreira Ruiz, Karina Andrighetti de Oliveira-Braga, Natalia Aparecida Nepomuceno, Paulo Manuel Pêgo-Fernandes, Stefan Gunther Tullius, Eberval Gadelha Figueiredo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Brain death is characterized by a generalized inflammatory response that results in multiorgan damage. This process is mainly mediated through cytokines, which amplify graft immunogenicity. We investigated the immunological response in a bra
Externí odkaz:
https://doaj.org/article/c377023aeb3c49e0bf911f268d1c356c
Autor:
Vinicius Luderer Dias, Karina Andrighetti de Oliveira Braga, Natalia Aparecida Nepomuceno, Liliane Moreira Ruiz, Juan David Ruiz Perez, Aristides Tadeu Correia, Luiz Carlos de Caires Junior, Ernesto Goulart, Mayana Zatz, Paulo Manuel Pêgo-Fernandes
Publikováno v:
Jornal Brasileiro de Pneumologia, Vol 47, Iss 4 (2021)
RESUMO Objetivo A escassez de pulmões viáveis ainda é um grande obstáculo para o transplante. As vítimas de trauma, que constituem potenciais doadores de pulmão, comumente apresentam choque hipovolêmico que acarreta inflamação e deterioraç
Externí odkaz:
https://doaj.org/article/b2d6b2af1f0147af910e548ea88dc21f
Autor:
Luis Gustavo Abdalla, Karina Andrighetti de Oliveira Braga, Natalia Aparecida Nepomuceno, Lucas Matos Fernandes, Marcos Naoyuki Samano, Paulo Manuel Pêgo-Fernandes
Publikováno v:
Jornal Brasileiro de Pneumologia, Vol 42, Iss 2, Pp 95-98 (2016)
Objective: To evaluate the use of ex vivo lung perfusion (EVLP) clinically to prepare donor lungs for transplantation. Methods: A prospective study involving EVLP for the reconditioning of extended-criteria donor lungs, the criteria for which include
Externí odkaz:
https://doaj.org/article/ec2bf694369b49668effcf618b3ab94d
Autor:
Arteiro Queiroz Menezes, Paulo Manuel Pêgo-Fernandes, Paulo Francisco Guerreiro Cardoso, Karina Andrighetti de Oliveira Braga, Natalia Aparecida Nepomuceno, Rogerio Pazetti, Aristides Tadeu Correia, Mauro Canzian, Jacqueline Klarosk Santim, Fabio Biscegli Jatene
Publikováno v:
Clinics, Vol 67, Iss 11, Pp 1309-1314 (2012)
OBJECTIVE: This study evaluated the performance of lungs that were preserved with different solutions (Celsior, Perfadex or saline) in an ex vivo rat lung perfusion system. METHODS: Sixty Wistar rats were anesthetized, anticoagulated and randomized i
Externí odkaz:
https://doaj.org/article/74a85c4981c14b38b6b29e8a14f3d6eb
Autor:
Edson Azevedo Simões, Paulo Francisco Guerreiro Cardoso, Paulo Manuel Pêgo-Fernandes, Mauro Canzian, Rogério Pazetti, Karina Andriguetti de Oliveira Braga, Natalia Aparecida Nepomuceno, Fabio Biscegli Jatene
Publikováno v:
Jornal Brasileiro de Pneumologia, Vol 38, Iss 4, Pp 461-469 (2012)
OBJETIVO: Comparar os achados histopatológicos e de apoptose em pulmões de ratos preservados em soluções low-potassium dextran (LPD, baixo potássio dextrana), histidine-tryptophan-ketoglutarate (HTK, histidina-triptofano-cetoglutarato) ou salina
Externí odkaz:
https://doaj.org/article/0b80c6cf50a44dc6a0393510f7d96c8f