Hyccin/FAM126A deficiency reduces glial enrichment and axonal sheath, which are rescued by overexpression of a plasma membrane-targeting PI4KIIIα in Drosophila

Autor: Qichao Zhang, Baozhu Zhang, Nastasia.K.H. Lim, Xiao Zhang, Shiquan Meng, Jens R. Nyengaard, Fude Huang, Wen-An Wang

Publikováno v: Zhang, Q, Zhang, B, Lim, N K H, Zhang, X, Meng, S, Nyengaard, J R, Huang, F & Wang, W A 2022, ' Hyccin/FAM126A deficiency reduces glial enrichment and axonal sheath, which are rescued by overexpression of a plasma membrane-targeting PI4KIIIα in Drosophila ', Biochemical and Biophysical Research Communications, vol. 589, pp. 71-77 . https://doi.org/10.1016/j.bbrc.2021.11.106

Hyccin/FAM126A mutations are linked to hypomyelination and congenital cataract disease (HCC), but whether and how Hyccin/FAM126A deficiency causes hypomyelination remains undetermined. This study shows Hyccin/FAM126A expression was necessary for the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8231b7737fa2d46a0c9bb19c28251a
https://pure.au.dk/portal/da/publications/hyccinfam126a-deficiency-reduces-glial-enrichment-and-axonal-sheath-which-are-rescued-by-overexpression-of-a-plasma-membranetargeting-pi4kiii-in-drosophila(438e2aab-6144-4607-be82-a6f3a6062b49).html