Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nassia Methia"'
Autor:
D Cosman, Nassia Methia, Monique Titeux, C Florindo, R Nador, K Schooley, Najet Debili, I Dusanter-Fourt, M Charon, Françoise Wendling
Publikováno v:
Blood. 85:391-401
The Mpl receptor (Mpl-R) is a cytokine receptor belonging to the hematopoietin receptor superfamily for which a ligand has been recently characterized. To study the lineage distribution of Mpl-R in normal hematopoietic cells, we developed a monoclona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fdfb599f4ccf954b94c68c5d242103e
https://doi.org/10.1182/blood.v85.2.391.bloodjournal852391
https://doi.org/10.1182/blood.v85.2.391.bloodjournal852391
Autor:
Nassia Methia, Françoise Wendling, Monique Titeux, Janine Breton-Gorius, Najet Debili, Mark Teepe, Eugene Maraskovsky, David Cosman, William Vainchenker, Christina Florindo
Publikováno v:
Nature. 369:571-574
Megakaryocytopoiesis is the cellular developmental process that leads to platelet production. At least two humoral growth factors may be necessary for megakaryocyte proliferation and maturation. One is a megakaryocyte-colony stimulating factor (MK-CS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb3c1ed68b38ab8efd12adad87ba632f
https://doi.org/10.1038/369571a0
https://doi.org/10.1038/369571a0
Publikováno v:
Blood. 98(5)
To examine the role of the platelet adhesion molecule von Willebrand factor (vWf) in atherogenesis, vWf-deficient mice (vWf−/−) were bred with mice lacking the low-density lipoprotein receptor (LDLR−/−) on a C57BL/6J background. LDLR−/−vW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cadc02d09dae4b602d3c92abe550d744
https://pubmed.ncbi.nlm.nih.gov/11520791
https://pubmed.ncbi.nlm.nih.gov/11520791
Publikováno v:
European journal of cell biology. 78(12)
Sorting of von Willebrand factor precursor (pro-vWf) from the trans-Golgi network to secretory granules (Weibel-Palade bodies) is critical for its conversion to the biologically active highly multimeric form, as well as for regulated secretion by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9066718379e2d0fed40de5771672939
https://pubmed.ncbi.nlm.nih.gov/10669107
https://pubmed.ncbi.nlm.nih.gov/10669107
Autor:
Cécile V. Denis, Richard O. Hynes, Nassia Methia, Mollie Ullman-Cullere, Helen Rayburn, Denisa D. Wagner, Paul S. Frenette
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(16)
von Willebrand factor (vWf) deficiency causes severe von Willebrand disease in humans. We generated a mouse model for this disease by using gene targeting. vWf-deficient mice appeared normal at birth; they were viable and fertile. Neither vWf nor vWf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa975565065642917e5d988731401022
https://pubmed.ncbi.nlm.nih.gov/9689113
https://pubmed.ncbi.nlm.nih.gov/9689113
Publikováno v:
Thrombosis and haemostasis. 74(1)
v-mpl is a mouse oncogene that is part of the genome of the myeloproliferative leukemia virus (MPLV). The cellular homolog gene c-mpl encodes an hematopoietic cytokine receptor mainly restricted to the megakaryocytic lineage of differentiation. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33407e828cbd3ec113a9020d442e308e
https://pubmed.ncbi.nlm.nih.gov/8578519
https://pubmed.ncbi.nlm.nih.gov/8578519
Publikováno v:
Blood. 82(5)
The proto-oncogene c-mpl encodes a protein whose sequence shares striking homologies with members of the highly conserved hematopoietin receptor superfamily. This gene had been transduced in a truncated form by the acute leukemogenic murine Myeloprol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf4e6528f5e3dc3f7af1873a12e034e
https://pubmed.ncbi.nlm.nih.gov/7689867
https://pubmed.ncbi.nlm.nih.gov/7689867
Publikováno v:
médecine/sciences. 10:874
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7521fc0a1fe95a9c3ec27d6e8762221
https://doi.org/10.4267/10608/2722
https://doi.org/10.4267/10608/2722
Publikováno v:
médecine/sciences. 10:114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4e8839dc1b8e45f6232d8aae703d095
https://doi.org/10.4267/10608/2494
https://doi.org/10.4267/10608/2494
Autor:
Nassia Methia, Maria Economopoulos, Denisa D. Wagner, Kennard L. Thomas, Patrick Andre, Ali Hafezi-Moghadam
Publikováno v:
Europe PubMed Central
BACKGROUND: Apolipoprotein E (apoE) mediates lipoprotein uptake by receptors such as the LDL receptor (LDLR). The isoform apoE4 has been linked to Alzheimer's disease and to poor outcomes after brain injury. Astrocytes that induce blood brain barrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b025c58af621ba4d449b58146ae79b
http://europepmc.org/abstract/med/11844869
http://europepmc.org/abstract/med/11844869
