Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nasser M. Qtaishat"'
Publikováno v:
Analytical Biochemistry. 432:49-57
This study reports the preparation and characterization of cysteine-terminated B-domain (Bd-cys) of Staphylococcus aureus protein A, in combination with immunoglobulin G (IgG) antibodies directed against the ρ1 and α1 subunits of GABA(A) receptors,
Publikováno v:
Current Eye Research. 32:1073-1082
Using an in vivo radiolabeling technique, we investigated the movement of retinoid into the retinal pigment epithelium (RPE) of the abcr-/- mouse, which lacks the photoreceptor ABCR protein and is a model for Stargardt disease. Eye tissues and serum
Publikováno v:
Journal of Neuroscience Methods. 151:97-105
The present paper describes the design, construction and testing of a temperature-sensitive N -isopropylacrylamide hydrogel device for studying the controlled presentation of γ-aminobutyric acid (GABA) to GABA C membrane receptors expressed in Xenop
Publikováno v:
Experimental Eye Research. 81:455-463
All- trans retinol generated in rod photoreceptors upon the bleaching of rhodopsin is known to move from the rods to the retinal pigment epithelium (RPE), where it is enzymatically converted to 11- cis retinal in the retinoid visual cycle. Interphoto
Autor:
David R. Pepperberg, John R. Hetling, Thomas J. Park, Nasser M. Qtaishat, Machelle T. Pardue, Monica S. Baig-Silva, Dalia Y. Samaan, Christopher M. Comer
Publikováno v:
Journal of Comparative Physiology A. 191:317-330
The eyes and visual capacity of the naked mole-rat, Heterocephalus glaber, a subterranean rodent, were evaluated using anatomical, biochemical, and functional assays, and compared to other rodents of similar body size (mouse and gerbil). The eye is s
Autor:
Leslie W.-M. Fung, James Davis, Cynthia C. LaBrake, Denise M. Lusitani, Mark R. Kelley, Nasser M. Qtaishat, Richard N. Yu
Publikováno v:
Journal of Biological Chemistry. 269:25955-25958
The 106-amino acid sequence motifs of spectrin have been suggested to fold into stable structural domains, consisting mostly of coiled coils of triple helices. With the advent of molecular biology and biophysical techniques, structural studies of the
Publikováno v:
Investigative ophthalmologyvisual science. 49(6)
PURPOSE The ABCR protein of the rod outer segment is thought to facilitate movement of the all-trans retinal photoproduct of rhodopsin bleaching out of the disc lumen. This study was undertaken to investigate the extent to which ABCR deficiency affec
Autor:
Ting Huai Wu, Muayyad R. Al-Ubaidi, May Nour, Harris Ripps, Nasser M. Qtaishat, Janis Lem, Steven J. Fliesler, Muna I. Naash, Xi-Qin Ding, Dibyendu Chakraborty, Neal S. Peachey
Publikováno v:
The Journal of comparative neurology. 478(2)
Several mutations in the opsin gene have been associated with congenital stationary night blindness, considered to be a relatively nonprogressive disorder. In the present study, we examined the structural and functional changes induced by one of thes
Publikováno v:
Investigative ophthalmologyvisual science. 44(4)
PURPOSE. Mice with a targeted disruption of the gene encoding RPE65, a protein ordinarily highly expressed in the retinal pigment epithelium (RPE), accumulate abnormally high levels of all-trans retinyl ester in the RPE and exhibit very little 11-cis
Autor:
Dibyendu Chakraborty, T. H. Wu, Harris Ripps, Xi-Qin Ding, Muayyad R. Al-Ubaidi, Steven J. Fliesler, Muna I. Naash, Neal S. Peachey, Janis Lem, Nasser M. Qtaishat, May Nour
Publikováno v:
The Journal of Comparative Neurology. 480:250-250