Time-Course Analysis of Gene Expression During the Saccharomyces cerevisiae Hypoxic Response

Autor: Nasrine Bendjilali, Samuel MacLeon, Gurmannat Kalra, Stephen D. Willis, A. K. M. Nawshad Hossian, Erica Avery, Olivia Wojtowicz, Mark J. Hickman

Publikováno v: G3: Genes, Genomes, Genetics, Vol 7, Iss 1, Pp 221-231 (2017)

Many cells experience hypoxia, or low oxygen, and respond by dramatically altering gene expression. In the yeast Saccharomyces cerevisiae, genes that respond are required for many oxygen-dependent cellular processes, such as respiration, biosynthesis

Externí odkaz: https://doaj.org/article/235ab15fc679477ea149cb1387f0126e

A genome-wide investigation of copy number variation in patients with sporadic brain arteriovenous malformation.

Autor: Nasrine Bendjilali, Helen Kim, Shantel Weinsheimer, Diana E Guo, Pui-Yan Kwok, Jonathan G Zaroff, Stephen Sidney, Michael T Lawton, Charles E McCulloch, Bobby P C Koeleman, Catharina J M Klijn, William L Young, Ludmila Pawlikowska

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e71434 (2013)

Brain arteriovenous malformations (BAVM) are clusters of abnormal blood vessels, with shunting of blood from the arterial to venous circulation and a high risk of rupture and intracranial hemorrhage. Most BAVMs are sporadic, but also occur in patient

Externí odkaz: https://doaj.org/article/04907797385149b98403c9bdddf9e49e

Abstract WP426: Does Intracerebral Hemorrhage in Brain Arteriovenous Malformation Share Genetic Risk Factors With Primary Intracerebral Hemorrhage?

Autor: Nerissa U. Ko, Nasrine Bendjilali, Jonathan G. Zaroff, Ludmila Pawlikowska, Michael T. Lawton, Shantel Weinsheimer, Helen Kim, Charles E. McCulloch, Jeffrey Nelson

Publikováno v: Stroke. 49

Introduction: Sporadic brain arteriovenous malformations (BAVMs) are rare vascular lesions that are a major cause of intracerebral hemorrhage (ICH) in younger persons. Genetic risk factors for ICH in BAVM have not been firmly established. Late-onset

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb6c96bda189181add3440ce242bedab
https://doi.org/10.1161/str.49.suppl_1.wp426

Genome-wide association study of sporadic brain arteriovenous malformations

Autor: Charles E. McCulloch, Alfredo Puca, Shantel Weinsheimer, Nasrine Bendjilali, Ludmila Pawlikowska, Roberto Pola, Matthias Simon, Rustam Al-Shahi Salman, Jonathan G. Zaroff, J. Nelson, Catharina J.M. Klijn, Bobby P. C Koeleman, Helen Kim, Azize Bostroem, William L. Young, Carmelo Lucio Sturiale, Stephen Sidney, Diana E. Guo, Marco Maria Fontanella, Michael T. Lawton, Jonathan Berg

Publikováno v: Journal of Neurology, Neurosurgery, and Psychiatry, 87, 916-23
Weinsheimer, S, Bendjilali, N, Nelson, J, Guo, D E, Zaroff, J G, Sidney, S, McCulloch, C E, Al-Shahi Salman, R, Berg, J N, Koeleman, B P C, Simon, M, Bostroem, A, Fontanella, M, Sturiale, C L, Pola, R, Puca, A, Lawton, M T, Young, W L, Pawlikowska, L, Klijn, C J M, Kim, H 2016, ' Genome-wide association study of sporadic brain arteriovenous malformations ', Journal of Neurology, Neurosurgery & Psychiatry . https://doi.org/10.1136/jnnp-2015-312272
Journal of Neurology, Neurosurgery, and Psychiatry, 87, 9, pp. 916-23
Journal of Neurology, Neurosurgery and Psychiatry, 87(9), 916. BMJ Publishing Group
Journal of neurology, neurosurgery, and psychiatry, vol 87, iss 9

BACKGROUND: The pathogenesis of sporadic brain arteriovenous malformations (BAVMs) remains unknown, but studies suggest a genetic component. We estimated the heritability of sporadic BAVM and performed a genome-wide association study (GWAS) to invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b895b7ba23d6f6db69ea08dad6a2f30d
https://europepmc.org/articles/PMC4963303/

Common variants on 9p21.3 are associated with brain arteriovenous malformations with accompanying arterial aneurysms

Autor: Jeffrey Nelson, Steven W. Hetts, Jonathan G. Zaroff, Charles E. McCulloch, Ludmila Pawlikowska, Helen Kim, Nasrine Bendjilali, Mark R. Segal, Shantel Weinsheimer, Stephen Sidney, William L. Young

Publikováno v: Journal of neurology, neurosurgery, and psychiatry, vol 85, iss 11

Objective To investigate whether previously reported 9p21.3 single nucleotide polymorphisms (SNPs) are associated with risk of brain arteriovenous malformations (BAVM), which often have accompanying arterial aneurysms. Common variants in the 9p21.3 l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8121621a520ae730b186bf769d8fad96
https://escholarship.org/uc/item/0564g8cw