Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Nasreddine, El Omari"'
Autor:
Nasreddine El Omari, Saad Bakrim, Asaad Khalid, Ashraf N. Abdalla, Mohamed A. M. Iesa, Kawtar El Kadri, Siah Ying Tang, Bey Hing Goh, Abdelhakim Bouyahya
Publikováno v:
Natural Products and Bioprospecting, Vol 14, Iss 1, Pp 1-29 (2024)
Abstract Until recently, the main pharmaceuticals used to control cholesterol and prevent cardiovascular disease (CVD) were statin-related drugs, known for their historical side effects. Therefore, there is growing interest in exploring alternatives,
Externí odkaz:
https://doaj.org/article/9b5bc027757f431489faf17b01748a04
Autor:
Saad Bakrim, Naoufal El Hachlafi, Asaad Khalid, Ashraf N. Abdalla, Nasreddine El Omari, Sara Aboulaghras, Ashraf M. Sakran, Khang Wen Goh, Long Chiau Ming, Pakhrur Razi, Abdelhakim Bouyahya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116886- (2024)
Colorectal cancer (CRC) is one of the most significant forms of human cancer. It is characterized by its heterogeneity because several molecular factors are involved in contiguity and can link it to others without having a linear correlation. Among t
Externí odkaz:
https://doaj.org/article/8f4d65386e2a4c54963b5c6d27c66973
Autor:
Nasreddine El Omari, Asaad Khalid, Hafiz A. Makeen, Hassan A. Alhazmi, Mohammed Albratty, Syam Mohan, Ching Siang Tan, Long Chiau Ming, Jack Bee Chook, Abdelhakim Bouyahya
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33052- (2024)
The Food and Drug Administration (FDA) has approved vorinostat, also called Zolinza®, for its effectiveness in fighting cancer. This drug is a suberoyl-anilide hydroxamic acid belonging to the class of histone deacetylase inhibitors (HDACis). Its HD
Externí odkaz:
https://doaj.org/article/c4bef52742e643f699db2347ea611e5a
Autor:
Abdelhakim Bouyahya, Abdelaali Balahbib, Asaad Khalid, Hafiz A. Makeen, Hassan A. Alhazmi, Mohammed Albratty, Andi Hermansyah, Long Chiau Ming, Khang Wen Goh, Nasreddine El Omari
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e29718- (2024)
Diabetes is a complex disease that affects a large percentage of the world's population, and it is associated with several risk factors. Self-management poses a significant challenge, but natural sources have shown great potential in providing effect
Externí odkaz:
https://doaj.org/article/147f7be2dda846c68bab677fcfb6964e
Autor:
Abdelhakim Bouyahya, Saad Bakrim, Sara Aboulaghras, Kawtar El Kadri, Tarik Aanniz, Asaad Khalid, Ashraf N. Abdalla, Ahmed A. Abdallah, Chrismawan Ardianto, Long Chiau Ming, Nasreddine El Omari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116432- (2024)
Oxidative stress results from a persistent imbalance in oxidation levels that promotes oxidants, playing a crucial role in the early and sustained phases of DNA damage and genomic and epigenetic instability, both of which are intricately linked to th
Externí odkaz:
https://doaj.org/article/639baef7f07f41c88aa154e1eb5d1266
Autor:
Abdelhakim Bouyahya, Saad Bakrim, Imane Chamkhi, Douae Taha, Nasreddine El Omari, Naoual El Mneyiy, Naoufal El Hachlafi, Mohamed El-Shazly, Asaad Khalid, Ashraf N. Abdalla, Khang Wen Goh, Long Chiau Ming, Bey Hing Goh, Tarik Aanniz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115989- (2024)
Cyanobacteria and microalgae contain various phytochemicals, including bioactive components in the form of secondary metabolites, namely flavonoids, phenolic acids, terpenoids, and tannins, with remarkable anticancer effects. This review highlights t
Externí odkaz:
https://doaj.org/article/75ab4aff174f43f29de5d0b093ec95d1
Autor:
Saad Bakrim, Nasreddine El Omari, Eman Jamil Khan, Asaad Khalid, Ashraf N. Abdalla, Jack Bee Chook, Khang Wen Goh, Long Chiau Ming, Sara Aboulaghras, Abdelhakim Bouyahya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115783- (2023)
Nuclear receptors (NRs) represent intracellular proteins that function as a signaling network of transcriptional factors to control genes in response to a variety of environmental, dietary, and hormonal stimulations or serve as orphan receptors lacki
Externí odkaz:
https://doaj.org/article/216412ff993d4feb9cf06c6e7a064324
Autor:
Nasreddine El Omari, Abdelaali Balahbib, Saad Bakrim, Taoufiq Benali, Riaz Ullah, Amal Alotaibi, Hanae Naceiri El Mrabti, Bey Hing Goh, Seng-Kai Ong, Long Chiau Ming, Abdelhakim Bouyahya
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21222- (2023)
Lavandula stoechas, a Mediterranean plant, renowned in traditional medicine for its health benefits, is also arousing strong interest associated with its essential oils (EOs) with promising therapeutic properties. The aim of this study was to analyze
Externí odkaz:
https://doaj.org/article/aaeb656e86ab4551bb05505ba96d1c3f
Autor:
Nasreddine El Omari, Saad Bakrim, Asaad Khalid, Mohammed Albratty, Ashraf N. Abdalla, Learn-Han Lee, Khang Wen Goh, Long Chiau Ming, Abdelhakim Bouyahya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115212- (2023)
Cancer progression is strongly affected by epigenetic events in addition to genetic modifications. One of the key elements in the epigenetic control of gene expression is histone modification through acetylation, which is regulated by the synergy bet
Externí odkaz:
https://doaj.org/article/00a245c40d244199a61d642ce4976a7c
Autor:
Nasreddine El Omari, Learn-Han Lee, Saad Bakrim, Hafiz A. Makeen, Hassan A. Alhazmi, Syam Mohan, Asaad Khalid, Long Chiau Ming, Abdelhakim Bouyahya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114774- (2023)
Romidepsin, also known as NSC630176, FR901228, FK-228, FR-901228, depsipeptide, or Istodax®, is a natural molecule produced by the Chromobacterium violaceum bacterium that has been approved for its anti-cancer effect. This compound is a selective hi
Externí odkaz:
https://doaj.org/article/d1da66ffb0ad4dd580886e8d305c06bf