Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood

Autor: Nasif, Sofia, de Souza, Flavio S. J., González, Laura E., Yamashita, Miho, Orquera, Daniela P., Low, Malcolm J., Rubinstein, Marcelo

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2015 Apr . 112(15), E1861-E1870.

Externí odkaz: https://www.jstor.org/stable/26462254

Corrections and Retractions

Autor: Schwartz, Craig P., Uejio, Janel S., Duffin, Andrew M., England, Alice H., Kelly, Daniel N., Prendergast, David, Saykally, Richard J., Franchini, Lucía F., López-Leal, Rodrigo, Nasif, Sofía, Beati, Paula, Gelman, Diego M., Low, Malcolm J., de Souza, Flávio J. S., Rubinstein, Marcelo

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2011 Dec . 108(51), 20850-20850.

Externí odkaz: https://www.jstor.org/stable/23077334

CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells

Autor: Reber, Stefan, Mechtersheimer, Jonas Matthias, Nasif, Sofia, Benitez, Julio Aguila, Colombo, Martino, Domanski, Michal, Jutzi, Daniel, Hedlund, Eva, Ruepp, Marc-David, Matera, A. Gregory

Publikováno v: Molecular Biology of the Cell
Reber, Stefan; Mechtersheimer, Jonas Matthias; Nasif, Sofia; Benitez, Julio Aguila; Colombo, Martino; Domanski, Michal; Jutzi, Daniel; Hedlund, Eva; Ruepp, Marc-David; Matera, A. Gregory (2018). CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells. Molecular biology of the cell, 29(2), pp. 75-83. American Society for Cell Biology 10.1091/mbc.E17-05-0288
Reber, S, Mechtersheimer, J, Nasif, S, Benitez, J A, Colombo, M, Domanski, M, Jutzi, D, Hedlund, E & Ruepp, M-D 2018, ' CRISPR-Trap : a clean approach for the generation of gene knockouts and gene replacements in human cells ', Molecular Biology of the Cell, vol. 29, no. 2, pp. 75-83 . https://doi.org/10.1091/mbc.e17-05-0288

Conventional nonhomologous end joining–based gene knockouts can lead to the production of C-terminally truncated proteins with potentially residual or dominant negative functions. Combining CRISPR/Cas9 with gene traps targeting the first intron (CR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3c9a0a214fcda839329c1b22d1afd7

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