Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nasiema Allie"'
Autor:
Kudzanai Ian Tapfuma, Kudakwashe Nyambo, Lucinda Baatjies, Marshal Keyster, Lukhanyo Mekuto, Liezel Smith, Nasiema Allie, Andre Gareth Loxton, Rehana Malgas-Enus, Vuyo Mavumengwana
Publikováno v:
SN Applied Sciences, Vol 4, Iss 5, Pp 1-19 (2022)
Abstract Tuberculosis (TB) is a persistent lung infection caused by Mycobacterium tuberculosis. The disease is characterized by high mortality rates of over 1 million per year. Unfortunately, the potency and effectiveness of currently used anti-TB dr
Externí odkaz:
https://doaj.org/article/28a29061eb274dc69cd54d870e6b5034
Autor:
Kudzanai Ian Tapfuma, Kudakwashe Nyambo, Francis Adu-Amankwaah, Lucinda Baatjies, Liezel Smith, Nasiema Allie, Marshall Keyster, Andre G. Loxton, Mkhuseli Ngxande, Rehana Malgas-Enus, Vuyo Mavumengwana
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12406- (2022)
The number and diversity of drugs in the tuberculosis (TB) drug development process has increased over the years, yet the attrition rate remains very high, signaling the need for continued research in drug discovery. In this study, crude secondary me
Externí odkaz:
https://doaj.org/article/fb39a0124d72440db551a47e61c24fd7
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 23, Iss 5, Pp 680-690 (2020)
Objective(s): This study aimed to explore the contribution of tumor necrosis factor (TNF) in the recruitment of B-cell and secretion of immunoglobulins (Igs) during cerebral tuberculosis (TB).Materials and Methods: In this work, the contributing role
Externí odkaz:
https://doaj.org/article/916fb9542d194bb0ba5a3232e0808f15
Autor:
Ivy Dambuza, Roanne Keeton, Nasiema Allie, Nai-Jen Hsu, Philippa Randall, Boipelo Sebesho, Lizette Fick, Valerie J F Quesniaux, Muazzam Jacobs
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e25121 (2011)
Of those individuals who are infected with M. tuberculosis, 90% do not develop active disease and represents a large reservoir of M. tuberculosis with the potential for reactivation of infection. Sustained TNF expression is required for containment o
Externí odkaz:
https://doaj.org/article/e264c71eab914fe3af80df35a7d8bbf4
Autor:
Kudzanai I. Tapfuma, Annamé Lourens, Lucinda Baatjies, Nasiema Allie, Andre G. Loxton, Vuyo Mavumengwana, Rehana Malgas-Enus
Publikováno v:
Materials Today Communications. 34:105098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82e3520af568d4d9c1828e66950f5190
https://doi.org/10.1016/j.mtcomm.2022.105098
https://doi.org/10.1016/j.mtcomm.2022.105098
Autor:
Roanne Keeton, Bernhard Ryffel, Valérie F. J. Quesniaux, Muazzam Jacobs, Nai-Jen Hsu, Nasiema Allie, Ngiambudulu M. Francisco
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2017, 8, ⟨10.3389/fimmu.2017.00180⟩
Frontiers in Immunology, Frontiers, 2017, 8, ⟨10.3389/fimmu.2017.00180⟩
Tuberculosis of the central nervous system (CNS-TB) is a devastating complication of tuberculosis, and tumor necrosis factor (TNF) is crucial for innate immunity and controlling the infection. TNF is produced by many cell types upon activation, in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7bb184ac619000ba07188c21bff15e
Autor:
Ivy M. Dambuza, Muazzam Jacobs, Roanne Keeton, Nasiema Allie, Nai-Jen Hsu, Bernhard Ryffel, Valérie F. J. Quesniaux
Publikováno v:
Scientific Reports
The pleiotropic activities of TNF are mediated by two structurally related but functionally distinct type I transmembrane receptors, p55TNFR and p75TNFR expressed in most cell types, that can be cleaved and act as TNF scavengers. Here, we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02eef76b9459fcc4aa07316968bc0262
https://pubmed.ncbi.nlm.nih.gov/27995986
https://pubmed.ncbi.nlm.nih.gov/27995986
Autor:
Valérie F. J. Quesniaux, Analbery Monteiro, Muazzam Jacobs, Sergei I. Grivennikov, Nasiema Allie, Cecile Fremond, Sergei A. Nedospasov, Shreemanta K. Parida, Daniela Carlos, Bernhard Ryffel, Arina Samarina, Marc Le Bert, Dieudonnée Togbe, Tania Botha
Publikováno v:
Microbes and Infection
Microbes and Infection, Elsevier, 2007, 9 (5), pp.623-8. ⟨10.1016/j.micinf.2007.02.002⟩
Microbes and Infection, Elsevier, 2007, 9 (5), pp.623-8. ⟨10.1016/j.micinf.2007.02.002⟩
Tumor necrosis factor (TNF) is critical and non-redundant to control Mycobacterium tuberculosis infection and cannot be replaced by other proinflammatory cytokines. Overproduction of TNF may cause immunopathology, while TNF neutralization reactivates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f3398fffd32f0f9fd446b5c72f233a
https://doi.org/10.1016/j.micinf.2007.02.002
https://doi.org/10.1016/j.micinf.2007.02.002
Publikováno v:
Immunology. 100:494-501
Interleukin-10 (IL-10) down-regulates T helper type 1 cell and macrophage functions. As IL-10 is induced along with tumour necrosis factor (TNF) and IL-12 in mycobacterial infection, we asked whether endogenous IL-10 plays a role in the antimycobacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b59bd3fc7686ceff37ae40a36babdd32
https://doi.org/10.1046/j.1365-2567.2000.00053.x
https://doi.org/10.1046/j.1365-2567.2000.00053.x
Publikováno v:
Clinical Immunology. 94:192-199
Neutralization of TNF or disruption of TNF-R1 leads to fatal Mycobacterium bovis BCG infection. Here we used TNF-LT-alpha-deficient mice to test whether a complete disruption of TNF and LT-alpha reduces further host resistance to BCG infection. The b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af06d3c4d6b2c364000a050f911eea9b
https://doi.org/10.1006/clim.2000.4835
https://doi.org/10.1006/clim.2000.4835