Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nasi Mian"'
Autor:
Clare E. Beesley, Nasi Mian, Anuska Mann, Kevin Mills, Geoffrey Keir, Peter E. Clayton, Viki C. Worthington, Stephanie Grunewald, James I. Langridge, Marie Jackson, Liz Young, Philippa B. Mills, Bryan Winchester
Publikováno v:
PROTEOMICS. 6:2295-2304
A method for the diagnosis of the congenital disorders of glycosylation type I (CDG-I) by SELDI-TOF-MS of serum transferrin immunocaptured on protein chip arrays is described. The underglycosylation of glycoproteins in CDG-I produces glycoforms of tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d97b240cbf40f89081349fcbcf3634
https://doi.org/10.1002/pmic.200500682
https://doi.org/10.1002/pmic.200500682
Publikováno v:
Clinical Science. 107:37-45
Poor fetal and infant nutrition has been linked to impaired glucose tolerance in later life. We studied the effect of protein deficiency during gestation and the suckling period in a rat model and found that poor nutrition ‘programmes’ pancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec9ae82149cf73115f16dad6321a711
https://doi.org/10.1042/cs20030350
https://doi.org/10.1042/cs20030350
Publikováno v:
Prenatal Diagnosis. 18:693-699
Two pregnancies at risk for the carbohydrate-deficient glycoprotein syndrome Type 1A (CDG1A, phosphomannomutase deficient) were monitored by enzyme and genetic linkage analyses. The index case in both families had a proven deficiency of phosphomannom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b75f4cc7391a7318927bef6b4522853
https://doi.org/10.1002/(sici)1097-0223(199807)18:7<693::aid-pd335>3.0.co
https://doi.org/10.1002/(sici)1097-0223(199807)18:7<693::aid-pd335>3.0.co
Autor:
Nasi Mian, Geoffrey Keir, Andrew W. Johnson, J. Charlwood, Peter E. Clayton, Bryan Winchester
Publikováno v:
Journal of Inherited Metabolic Disease. 20:817-827
The carbohydrate-deficient glycoprotein syndrome (CDGS) is a group of disorders characterized biochemically by abnormal glycosylation of serum and cellular glycoproteins. It has been classified into four forms on the basis of the isoelectric focusing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e505392e1da964dfa3658a0d16599890
https://doi.org/10.1023/a:1005380003902
https://doi.org/10.1023/a:1005380003902
Autor:
Raymond A. Dwek, Oleg Iourin, Pauline M. Rudd, Nasi Mian, Geoffrey Keir, Bryan Winchester, Taj S. Mattu
Publikováno v:
Glycoconjugate Journal. 13:1031-1042
One of the biochemical characteristics of carbohydrate deficient glycoprotein syndromes is the presence of abnormal glycoforms in serum transferrin. Both glycoform heterogeneity and variable site occupancy may, in principle, lead to the generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f283dd3e01e67e372a71a96ff36bf69d
https://doi.org/10.1007/bf01053199
https://doi.org/10.1007/bf01053199
Autor:
Nasi Mian, Philippa B. Mills, Peter E. Clayton, Andrew W. Johnson, Bryan Winchester, Kevin Mills
Publikováno v:
Glycobiology. 13(2)
Conditions under which the glycosylation capacity of cells is limited provide an opportunity for studying the efficiency of site-specific glycosylation and the role of glycosylation in the maturation of glycoproteins. Congenital disorders of glycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e096065cc5b71ff0b4598c1a8abe10b3
https://pubmed.ncbi.nlm.nih.gov/12626422
https://pubmed.ncbi.nlm.nih.gov/12626422
Publikováno v:
Glycobiology. 8(4)
The glycosylation of serum transferrin from galactosemic patients with a deficiency of galactose-1-phosphate uridyl transferase (EC 2. 7.7 12) is abnormal but becomes normal after treatment with a galactose-free diet. To understand the structural and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b875fec3680cf85a78fa926d950c297f
https://pubmed.ncbi.nlm.nih.gov/9499382
https://pubmed.ncbi.nlm.nih.gov/9499382
Autor:
Peter E. Clayton, Nasi Mian
Publikováno v:
American Journal of Medical Genetics. 56:289-289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::701bd9ce7d695cc4b4fc6ff983c16916
https://doi.org/10.1002/ajmg.1320560312
https://doi.org/10.1002/ajmg.1320560312
Publikováno v:
Biochemical Journal. 181:377-385
Chemically sulphated glycopeptides (derived from pig duodenal mucosa) inhibited Clostridium perfringens neuraminidase (EC 3.2.1.18) activity in a pH-dependent manner. Analysis of inhibition kinetics data indicated that, although the enzyme inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3abe29a5744d56e2c8a071fe1b239cd
https://doi.org/10.1042/bj1810377
https://doi.org/10.1042/bj1810377
Autor:
Nasi Mian
Publikováno v:
Biochemical Journal. 237:343-357
A high-Mr phosphoprotein (Mr 442,000) was purified from Nonidet-P-40-solubilized plasma membranes of cultured human skin fibroblasts. The protein comprised one 200,000-Mr subunit consisting of 116,000- and 84,000-Mr polypeptides and two identical 121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07053ad9c1e823763008910505ac8dcb
https://doi.org/10.1042/bj2370343
https://doi.org/10.1042/bj2370343