Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nashitha Kabir"'
Autor:
Christopher O’Shea, James Winter, S. Nashitha Kabir, Molly O’Reilly, Simon P. Wells, Olivia Baines, Laura C. Sommerfeld, Joao Correia, Ming Lei, Paulus Kirchhof, Andrew P. Holmes, Larissa Fabritz, Kashif Rajpoot, Davor Pavlovic
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/d1ada08902cf44d48c42bfc7bf032f79
Autor:
Christopher O’Shea, James Winter, S. Nashitha Kabir, Molly O’Reilly, Simon P Wells, Olivia Baines, Laura C. Sommerfeld, Joao Correia, Ming Lei, Paulus Kirchhof, Andrew P. Holmes, Larissa Fabritz, Kashif Rajpoot, Davor Pavlovic
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-12 (2022)
Abstract Optical mapping of animal models is a widely used technique in pre-clinical cardiac research. It has several advantages over other methods, including higher spatial resolution, contactless recording and direct visualisation of action potenti
Externí odkaz:
https://doaj.org/article/f56558f5ecfb42e4809246dad06922f8
Autor:
Jasmeet S. Reyat, Winnie Chua, Victor R. Cardoso, Anika Witten, Peter M. Kastner, S. Nashitha Kabir, Moritz F. Sinner, Robin Wesselink, Andrew P. Holmes, Davor Pavlovic, Monika Stoll, Stefan Kääb, Georgios V. Gkoutos, Joris R. de Groot, Paulus Kirchhof, Larissa Fabritz
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
BACKGROUND Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation.METHO
Externí odkaz:
https://doaj.org/article/f0ceb91cf1c64eb28dce8b403521e23a
Autor:
S. Nashitha Kabir, Jasmeet S. Reyat, Antony J. Workman, Priyanka Saxena, Dannie Fobian, Davor Pavlovic, Larissa Fabritz, Clara Apicella, Stefan M. Kuhlmann, Godfrey L. Smith, Paulus Kirchhof, Molly O’Reilly, Andrew P. Holmes, Fahima Syeda, Suranjana Gupta, Christopher O’Shea
Publikováno v:
Heart Rhythm. 18:1212-1220
Background Although atrial fibrillation ablation is increasingly used for rhythm control therapy, antiarrhythmic drugs (AADs) are commonly used, either alone or in combination with ablation. The effectiveness of AADs is highly variable. Previous work
Autor:
Laura C. Sommerfeld, Andrew P. Holmes, Ting Y. Yu, Christopher O’Shea, Deirdre M. Kavanagh, Jeremy M. Pike, Thomas Wright, Fahima Syeda, Areej Aljehani, Tania Kew, Victor R. Cardoso, S. Nashitha Kabir, Claire Hepburn, Priyanka M. Menon, Sophie Broadway-Stringer, Molly O’Reilly, Anika Witten, Lisa Fortmueller, Susanne Lutz, Alexandra Kulle, Georgios V. Gkoutos, Davor Pavlovic, Wiebke Arlt, Gareth G. Lavery, Richard Steeds, Katja Gehmlich, Monika Stoll, Paulus Kirchhof, Larissa Fabritz
Androgenic anabolic steroids (AAS) are commonly abused by young men. Male sex associates with earlier manifestation of common and rare cardiac conditions including atrial fibrillation and arrhythmogenic right ventricular cardiomyopathy (ARVC). Clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320bdecc137f36457f502ef7283eb6a9
https://doi.org/10.1101/2022.06.03.494748
https://doi.org/10.1101/2022.06.03.494748
Autor:
Julius Obergassel, Molly O’Reilly, Christopher O’Shea, Paulus Kirchhof, Lars Eckardt, Larissa Fabritz, L C Sommerfeld, Fahima Syeda, S. Nashitha Kabir
Publikováno v:
Europace
Aims Genetically altered mice are powerful models to investigate mechanisms of atrial arrhythmias, but normal ranges for murine atrial electrophysiology have not been robustly characterized. Methods and results We analyzed results from 221 electrophy
Autor:
Sian O' Brien, Andrew P. Holmes, Daniel M. Johnson, S. Nashitha Kabir, Christopher O' Shea, Molly O' Reilly, Adelisa Avezzu, Jasmeet S. Reyat, Amelia W. Hall, Clara Apicella, Patrick T. Ellinor, Steven Niederer, Nathan R. Tucker, Larissa Fabritz, Paulus Kirchhof, Davor Pavlovic
Atrial fibrillation (AF) affects over 1% of the population and is a leading cause of stroke and heart failure in the elderly. A feared side effect of sodium channel blocker therapy, ventricular pro-arrhythmia, appears to be relatively rare in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978c50e204b5bb0d3afc935e4259b287
http://oro.open.ac.uk/81833/1/OBrien_et_al_Atrial_vs_Ventricular_Sodium_JMCC_13_01_2022.pdf
http://oro.open.ac.uk/81833/1/OBrien_et_al_Atrial_vs_Ventricular_Sodium_JMCC_13_01_2022.pdf
Autor:
Silvio Weber, Maximilian Hoffmann, Susanne Kämmerer, Molly O’Reilly, Ali El-Armouche, Mirna S. Sadek, Sems Malte Tugtekin, Ben Wielockx, Pauline Wimberger, Mario Günscht, L C Sommerfeld, Natalie Herzog, Ursula Ravens, Larissa Fabritz, Stefan Rose-John, Jan-Heiner Küpper, Kaomei Guan, Erik Klapproth, S. Nashitha Kabir, Tomasz Kolanowski, Jan Dominik Kuhlmann, Michael Wagner, Manuel Mayr, Stefanie Meyer-Roxlau, Stephan R Künzel, Konrad Grützmann, Stanley Nattel, Karolina Künzel, Xiaoke Yin, C. Piorkowski, Johanna S E Rausch, Dobromir Dobrev
Publikováno v:
Circulation Research
Supplemental Digital Content is available in the text.
Rationale: Fibrosis promotes the maintenance of atrial fibrillation (AF), making it resistant to therapy. Improved understanding of the molecular mechanisms leading to atrial fibrosis will o
Rationale: Fibrosis promotes the maintenance of atrial fibrillation (AF), making it resistant to therapy. Improved understanding of the molecular mechanisms leading to atrial fibrosis will o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e048dfbc460665ba37f1c2b2bbe8d1
https://www.ncbi.nlm.nih.gov/pubmed/34433292
https://www.ncbi.nlm.nih.gov/pubmed/34433292
Autor:
Nashitha Kabir, Eloisa Arbustini, Beatriz Ortiz-Bonnin, Sven Dittmann, Francesca Gualandi, Roland F.R. Schindler, Sven Zumhagen, Birgit Stallmeyer, Rita Selvatici, Alessandra Ferlini, Corinna Friedrich, Susanne Rinné, Lisa Fortmüller, Thomas Brand, Eric Schulze-Bahr, Ursula Herbort-Brand, Niels Decher, Aytug K. Kiper, Larissa Fabritz, Claudio Rapezzi
Publikováno v:
Journal of molecular and cellular cardiology. 145
Despite recent progress in the understanding of cardiac ion channel function and its role in inherited forms of ventricular arrhythmias, the molecular basis of cardiac conduction disorders often remains unresolved. We aimed to elucidate the genetic b
Autor:
Stefan Kääb, Paulus Kirchhof, Moritz F. Sinner, Winnie Chua, Robin Wesselink, Georgios V. Gkoutos, Monika Stoll, S. Nashitha Kabir, Jasmeet S. Reyat, Peter Kastner, Anika Witten, Joris R. de Groot, Davor Pavlovic, Larissa Fabritz, Victor Roth Cardoso, Andrew P. Holmes
Publikováno v:
JCI INSIGHT
JCI Insight, Vol 5, Iss 16 (2020)
JCI Insight
JCI INSIGHT, 5(16):139179. American Society for Clinical Investigation
JCI insight, 5(16):e139179. The American Society for Clinical Investigation
JCI Insight, Vol 5, Iss 16 (2020)
JCI Insight
JCI INSIGHT, 5(16):139179. American Society for Clinical Investigation
JCI insight, 5(16):e139179. The American Society for Clinical Investigation
BACKGROUND Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation. METH