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pro vyhledávání: '"Naser Uddin Hoti"'
Autor:
Theodore L. DeWeese, Ronald Rodriguez, Shawn E. Lupold, Wasim H. Chowdhury, Tamara Jane Johnson, Naser Uddin Hoti, Chunyan Liu, Ying Li, Yonggang Zhang
Publikováno v:
Cancer gene therapy
Conditionally replicating adenoviruses (CRAds) utilize tissue specific promoters to control the expression of the early genes, E1A and E1B, to preferentially replicate and lyse tumor cells (oncolysis). Previous CRAds used in prostate cancer gene ther
Publikováno v:
Journal of Cancer Therapy. :1012-1019
Prostate specific conditionally replicating adenoviruses (CRAd) are made by placing a tissue specific promoter upstream of one or more of the viral genes required for replication (e.g., E1A, E1B). However, one major problem associated with these vect
Publikováno v:
Molecular Therapy. 13:S118