Zobrazeno 1 - 10 of 127 pro vyhledávání: '"Naseem Km"'
1
Platelet Flow Cytometry: Instrument Setup, Controls, and Panel Performance
Autor: Spurgeon, BEJ, Naseem, KM
Platelet flow cytometry is widely used in cardiovascular medicine as the platelet surface is rich in clinical biomarkers. Surface profiling is critical in disease management, but current assays can abet clinical errors as they are suboptimal and pron
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::3ebef666e4a41c96fd776826f2c17100
https://eprints.whiterose.ac.uk/149331/1/CytometryB-2019-Spurgeon_Naseem_CYT_B.pdf
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3
cGMP signaling inhibits platelet shape change through regulation of the RhoA-Rho Kinase-MLC phosphatase signaling pathway
Autor: Aburima, A, Walladbegi, K, Wake, JD, Naseem, KM
Background: Platelet shape change, spreading and thrombus stability require activation of the actin cytoskeleton contractile machinery. The mechanisms controlling actin assembly to prevent unwanted platelet activation are unclear. Objectives: We exam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ba2964060abc39470c56ea550613fe9a
https://eprints.whiterose.ac.uk/132896/1/JTH-2017-Aburima.pdf
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4
Modification of tissue factor by peroxynitrite influences its procoagulant activity
Autor: Camille Ettelaie, Jacqueline M. Adam, Naseem Km, Bruckdorfer Kr, Nicola J. James, Nicholas J. Bradley
Publikováno v: FEBS letters. 429(3)
Peroxynitrite, a reactive oxidising species resulting from a reaction between nitric oxide and the superoxide anion, modifies proteins by nitration of certain amino acids such as tyrosine. Tissue factor (TF), a transmembrane protein, is expressed on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c4c56ef7c7c817f4ce52e26e95274f
https://pubmed.ncbi.nlm.nih.gov/9662446
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6
The synergism of hydrogen peroxide with plasma S-nitrosothiols in the inhibition of platelet activation
Autor: K R Bruckdorfer, S Chirico, Naseem Km, B Mohammadi
Earlier studies have shown that inhibition of aggregation of washed platelets (WP) by NO was enhanced almost 100-fold by H2O2. In the present study, the interactions of H2O2 with nitrosothiols, the influence of the presence of plasma and the mechanis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab52fbb44ec5fc6390998c8fa0b4be98
https://europepmc.org/articles/PMC1217683/
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7
The mechanism of inhibition of factor III (thromboplastin) activity by apolipoprotein B-100. Protein-protein interactions
Autor: K. Richard Bruckdorfer, Nicola J. James, B. R. Wilbourn, Naseem Km, Camille Ettelaie, Jacqueline M. Adam
Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 16(5)
Abstract Factor III (thromboplastin) activity is inhibited by apoB-100, but the mechanism of inhibition is unknown. By examining the effect of purified apoB-100 on factor III activity, we showed that apoB-100 can inhibit factor III via a different me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd3c0549f35c14b9f8b2b1a38418850
https://pubmed.ncbi.nlm.nih.gov/8963721
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9
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10
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