Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Naseem Khorram"'
Autor:
Jana H. Badrani, Allyssa N. Strohm, Lee Lacasa, Blake Civello, Kellen Cavagnero, Yung-An Haung, Michael Amadeo, Luay H. Naji, Sean J. Lund, Anthea Leng, Hyojoung Kim, Rachel E. Baum, Naseem Khorram, Monalisa Mondal, Grégory Seumois, Julie Pilotte, Peter W. Vanderklish, Heather M. McGee, Taylor A. Doherty
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The function of RNA binding proteins within innate lymphoid cells (ILC) has been partially characterised. Here the authors show that RBM3 functions to limit the type 2 immunity promoting activity of ILC2 partially through cysteinyl leukotriene 1 rece
Externí odkaz:
https://doaj.org/article/8f52f115894447729c3303cf626c6953
Autor:
Naseem Khorram, Anthea S. Leng, Rachel Baum, Jana Badrani, Taylor A. Doherty, Greggory Seumois, Hyojoung Kim, Kellen J. Cavagnero, Sean Lund, Luay H. Naji, Julie Pilotte, Monalisa Mondal, Lee Lecasa, Allyssa N. Strohm, Peter W. Vanderklish, Michael B. Amadeo
Innate lymphoid cells (ILCs) promote lung inflammation through cytokine production in diseases such as asthma. RNA-binding proteins (RBPs) are critical post-transcriptional regulators of cellular function, including inflammatory responses, though the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a26552c016c7d724756cd4d11442b646
https://doi.org/10.21203/rs.3.rs-45172/v1
https://doi.org/10.21203/rs.3.rs-45172/v1
Autor:
Jana H. Badrani, Michael Amadeo, Kellen Cavagnero, Luay H. Naji, Sean J. Lund, Anthea Leng, Lee Lacasa, Allyssa Strohm, Hyojoung Kim, Rachel E. Baum, Naseem Khorram, Monalisa Mondal, Grégory Seumois, Julie Pilotte, Peter W. Vanderklish, Taylor A. Doherty
Innate lymphoid cells (ILCs) promote lung inflammation through cytokine production in diseases such as asthma. RNA-binding proteins (RBPs) are critical post-transcriptional regulators of cellular function, including inflammatory responses, though the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8023e835c53c21ef1e7c6643ee8dee92
https://doi.org/10.1101/2020.07.27.223958
https://doi.org/10.1101/2020.07.27.223958
Autor:
Julie Pilotte, Luay H. Naji, Rachel Baum, Naseem Khorram, Peter W. Vanderklish, Taylor A. Doherty, Sean Lund, Kellen J. Cavagnero, Jana Badrani, Michael B. Amadeo
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:AB1
Publikováno v:
International Archives of Allergy and Immunology. 163:92-105
Background: Exposure to the fungal allergen Alternaria alternata as well as ryegrass pollen has been implicated in severe asthma symptoms during thunderstorms. We have previously shown that Alternaria extract induces innate type 2 lung inflammation i
Autor:
Naseem Khorram, Siwy Ling Yang, Sean Lund, Taylor A. Doherty, Rachel Baum, Kuang-Ren Chung, Hee-Kyoo Kim
Publikováno v:
Experimental Lung Research. 39:399-409
The fungal allergen Alternaria alternata is associated with development of asthma, though the mechanisms underlying the allergenicity of Alternaria are largely unknown. The aim of this study was to identify whether the MAP kinase homologue Fus3 of Al
Publikováno v:
Journal of Allergy and Clinical Immunology. 132:205-213
Background Cysteinyl leukotrienes (CysLTs) contribute to asthma pathogenesis, in part through cysteinyl leukotriene receptor 1 (CysLT1R). Recently discovered lineage-negative type 2 innate lymphoid cells (ILC2s) potently produce IL-5 and IL-13. Objec
Autor:
Naseem Khorram, Peter Rosenthal, Pejman Soroosh, Wei Duan, Michael Croft, Taylor A. Doherty, Heonsik Choi, Zbigniew Mikulski, Yan Fei Adams, Amit Mehta, David H. Broide
Publikováno v:
The Journal of Experimental Medicine
Lung-resident antigen-presenting macrophages promote tolerance to inhaled antigens via the induction of regulatory T cells.
Airway tolerance is the usual outcome of inhalation of harmless antigens. Although T cell deletion and anergy are likely
Airway tolerance is the usual outcome of inhalation of harmless antigens. Although T cell deletion and anergy are likely
Autor:
Taylor A. Doherty, Peter Rosenthal, Jae Youn Cho, Naseem Khorram, Dean Sheppard, Marina Miller, Alexa Pham, Kotaro Sugimoto, Michael Croft, David H. Broide
Publikováno v:
The Journal of Immunology. 188:2622-2629
The fungal allergen, Alternaria, is specifically associated with severe asthma, including life-threatening exacerbations. To better understand the acute innate airway response to Alternaria, naive wild-type (WT) mice were challenged once intranasally
Publikováno v:
Open Journal of Obstetrics and Gynecology. :283-286
Background: The objective of this study was to determine the effects of acupuncture treatment as an adjunctive therapy on the outcome of in vitro fertilization (IVF)/Intracytoplasmic Sperm Injection (ICSI). Material/Methods: We conducted a retrospect