Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies.

Autor: Izquierdo E; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Vorholt D; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Blakemore S; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Sackey B; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Nolte JL; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Barbarino V; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Schmitz J; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Nickel N; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Bachurski D; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Lobastova L; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Nikolic M; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Michalik M; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Brinker R; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Merkel O; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Franitza M; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Georgomanolis T; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; West German Genome Center (WGGC), Cologne, Germany., Neuhaus R; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Koch M; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Nasada N; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Knittel G; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Chapuy B; Department of Hematology, Oncology, and Cancer Immunology, Campus Benjamin Franklin, Charité - University Medical Center Berlin, corporate member of Free University Berlin and Humboldt-University Berlin, Berlin, Germany., Ludwig N; Institute for Human Genetics, University of Saarland, Homburg/Saar, Germany., Meese E; Institute for Human Genetics, University of Saarland, Homburg/Saar, Germany., Frenzel L; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Reinhardt HC; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and.; Clinic for Hematology and Stem Cell Transplantation, University Hospital Essen, University Duisburg-Essen, Essen, Germany; and., Peifer M; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Rebollido-Rios R; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Bruns H; Department of Internal Medicine, University of Erlangen, Erlangen, Germany., Krüger M; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Hallek M; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and., Pallasch CP; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn.; Cologne Excellence Cluster for Cellular Stress Responses in Ageing-Associated Diseases (CECAD), and.

Publikováno v: Blood [Blood] 2022 Jun 23; Vol. 139 (25), pp. 3617-3629.