Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Narumol, Chinookoswong"'
Autor:
Randy Hecht, Yue-Sheng Li, Jeonghoon Sun, Ed Belouski, Michael Hall, Todd Hager, Junming Yie, Wei Wang, Dwight Winters, Stephen Smith, Chris Spahr, Lei-Ting Tam, Zhongnan Shen, Shanaka Stanislaus, Narumol Chinookoswong, Yvonne Lau, Allen Sickmier, Mark Leo Michaels, Thomas Boone, Murielle M Véniant, Jing Xu
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49345 (2012)
Fibroblast growth factor 21 (FGF21) is a promising drug candidate for the treatment of type 2 diabetes. However, the use of wild type native FGF21 is challenging due to several limitations. Among these are its short half-life, its susceptibility to i
Externí odkaz:
https://doaj.org/article/4b03784bd0594b29a2d0316fd49362ba
Autor:
Hua Zhu Ke, Jin Wang, Jing Xu, Michael S. Ominsky, Murielle M. Véniant, Kelly S. Villasenor, Xiaodong Li, Benxian Liu, Narumol Chinookoswong, Rogely W. Boyce, Qing-Tian Niu, Philip Wong, Marina Stolina, Chun-Ya Han, Shanaka Stanislaus, Denise Dwyer, Michelle Chen, Frank Asuncion
Publikováno v:
Journal of Bone and Mineral Research. 32:834-845
Results of prior studies suggest that fibroblast growth factor 21 (FGF21) may be involved in bone turnover and in the actions of peroxisome proliferator-activated receptor (PPAR) α and γ in mice. We have conducted independent studies to examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed6a32d61aa304329a236f241c29735
https://doi.org/10.1002/jbmr.2936
https://doi.org/10.1002/jbmr.2936
Autor:
David W. Brankow, Shu-Chen Lu, Jing Xu, Shuying Liu, Shirley Steavenson, Colin V. Gegg, Richard A. Lindberg, Wei Gu, Narumol Chinookoswong, Murielle M. Véniant
Publikováno v:
Molecular Pharmacology. 75:901-907
Ghrelin is a 28-amino acid peptide secreted mainly by the stomach. Acyl-ghrelin, which binds to and activates the growth hormone secretagogue receptor type 1a (GHS-R1a), is considered to be the active form for its orexigenic effects. It has been demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295b85dcb2ee6b40eaa2abba9ecd4f50
https://doi.org/10.1124/mol.108.052852
https://doi.org/10.1124/mol.108.052852
Autor:
Xiaodong, Li, Shanaka, Stanislaus, Frank, Asuncion, Qing-Tian, Niu, Narumol, Chinookoswong, Kelly, Villasenor, Jin, Wang, Philip, Wong, Rogely, Boyce, Denise, Dwyer, Chun-Ya, Han, Michelle M, Chen, Benxian, Liu, Marina, Stolina, Hua Zhu, Ke, Michael S, Ominsky, Murielle M, Véniant, Jing, Xu
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 32(4)
Results of prior studies suggest that fibroblast growth factor 21 (FGF21) may be involved in bone turnover and in the actions of peroxisome proliferator-activated receptor (PPAR) α and γ in mice. We have conducted independent studies to examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60eb2df1cdd65dda9b0a20074f1b166f
https://pubmed.ncbi.nlm.nih.gov/27505721
https://pubmed.ncbi.nlm.nih.gov/27505721
Autor:
Reza Jazayeri, Mohenish K. Singh, Jin Lin Wang, Victoria Fernandez, Maziyar Saberi, James R. Davis, Narumol Chinookoswong, Zhi Qing Shi, Nancy Levin, Toby L. Smith, Ben B. Yaspelkis, Beatriz Trevino
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 280:E130-E142
In addition to suppressing appetite, leptin may also modulate insulin secretion and action. Leptin was administered here to insulin-resistant rats to determine its effects on secretagogue-stimulated insulin release, whole body glucose disposal, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ae7597b7c881441bcc2283caa605e8
https://doi.org/10.1152/ajpendo.2001.280.1.e130
https://doi.org/10.1152/ajpendo.2001.280.1.e130
Publikováno v:
Endocrinology. 140:2117-2124
We have recently shown that leptin enhances systemic insulin sensitivity and whole body glucose utilization in the rat. This study examines our hypothesis that leptin has differential effects in regulating glucose utilization among the tissues, i.e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d487994bd2933e2fffa20b283c7fa569
https://doi.org/10.1210/endo.140.5.6681
https://doi.org/10.1210/endo.140.5.6681
Autor:
Shu-Chen Lu, Murielle M. Véniant, Jen Weiszmann, Richard A. Lindberg, Jing Xu, Jennifer Patel, Yang Li, Jim Busby, Shanaka Stanislaus, Yue-Sheng Li, Hongfei Ge, Narumol Chinookoswong, Melissa Graham, Yvonne Y. Lau, Todd Hager, Randy Ira Hecht
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 297(5)
Recombinant fibroblast growth factor (FGF)21 has antihyperglycemic, antihyperlipidemic, and antiobesity effects in diabetic rodent and monkey models. Previous studies were confined to measuring steady-state effects of FGF21 following subchronic or ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa50d32f4650bb6641b1d183fd31ddc
https://pubmed.ncbi.nlm.nih.gov/19706786
https://pubmed.ncbi.nlm.nih.gov/19706786
Autor:
Jin Lin Wang, Xueming Qian, Narumol Chinookoswong, Zhi-Qing Shi, John Lu, Lars Eyde Theill, Gwyneth Chow
Publikováno v:
Endocrinology. 143(9)
We have conducted three studies to examine the role of TNFalpha in islet destruction in female nonobese diabetic mouse (NOD) mice, a model of human autoimmune diabetes, using polyethylene glycolated (PEGylated) soluble TNF receptor type I (PEG sTNF-R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad36ac224515597cff3279cdf7d3a210
https://pubmed.ncbi.nlm.nih.gov/12193562
https://pubmed.ncbi.nlm.nih.gov/12193562
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 279(6)
We examined a possible mechanistic interaction between leptin and thyroid hormones in rats with hypothyroidism induced by thyroidectomy (TX) and propylthiouracil administration. In study 1, the TX rats were treated by vehicle (V, n = 9) or by recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfa3106d58c9f062ae7a764880f5457
https://pubmed.ncbi.nlm.nih.gov/11093915
https://pubmed.ncbi.nlm.nih.gov/11093915
Autor:
Deborah A. Russell, Kathy K. Tucker, Robert C. Thompson, Tadahiko Kohno, Narumol Chinookoswong
Publikováno v:
The Journal of infectious diseases. 171(6)
The interleukin (IL)-1 receptor antagonist (Ra) and a polyethylene glycol-linked dimer of the type I soluble receptor of tumor necrosis factor (TNF), PEG-(rsTNF-RI)2, were used to determine whether maximal protection against lethality and organ dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0026e209db0c93ed58849d3c32a2dd4
https://pubmed.ncbi.nlm.nih.gov/7769288
https://pubmed.ncbi.nlm.nih.gov/7769288