Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Narsingh D. Agnish"'
Autor:
Kit A. Keller, Narsingh D. Agnish
Publikováno v:
Toxicological Sciences. 38:2-6
Based on a review of the pertinent literature and our own unpublished data, it is recommended that culling of rodent litters in the early postnatal period should be a standard practice in delivery-type reproduction studies. This, in turn, will reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7186b7f09b1bdc632016bad8a6d9a149
https://doi.org/10.1093/toxsci/38.1.2
https://doi.org/10.1093/toxsci/38.1.2
Autor:
Narsingh D. Agnish, Judith W. Henck, Ada H. C. Kung, Mercedes Serabian, Kim G. Hilbish, Andrew G Hendrickx, Joyce Mordenti, Joy A. Cavagnaro
Publikováno v:
Teratology. 53:185-195
Parke-Davis Pharmaceutical Research, Ann Arbor, Michigan 48105 (J.WH.); Miles, Inc., Elkhart, Indiana 46515 (K.G.H.); USFDA, Rockville, Maryland 20852 (M.A.S., J.A.C.); California Regional Primate Research Center, Davis, California 95616 (A.G.H.); Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd391ebeb6a7cec52fe46bbff7cb9a9
https://doi.org/10.1002/(sici)1096-9926(199603)53:3<185::aid-tera6>3.0.co
https://doi.org/10.1002/(sici)1096-9926(199603)53:3<185::aid-tera6>3.0.co
Publikováno v:
Fundamental and Applied Toxicology. 15:249-257
Experimental evidence exists to indicate that retinoids may act as detergents to disrupt biological membranes. Taurine, an amino sulfonic acid, has been shown to possess membrane-stabilizing and cytoprotective properties. This study was undertaken to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14d8ce985f622f48b0571de96e3b98a4
https://doi.org/10.1016/0272-0590(90)90052-l
https://doi.org/10.1016/0272-0590(90)90052-l
Publikováno v:
Teratology. 42:25-33
Sprague-Dawley female rats were treated with a single oral dose of 0 (vehicle), 10, or 25 mg/kg of etretinate (ET), an aromatic retinoid, on gestation day 6, 7, or 8. While treatment on day 8 with both dosages of ET was highly teratogenic, no evidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4df7d600e40cedd521728bfba07cbb
https://doi.org/10.1002/tera.1420420105
https://doi.org/10.1002/tera.1420420105
Autor:
L. Juhasz, S. Chari, Narsingh D. Agnish, M. Kromka, H. Rudiger, Horst Staudner, Christian Eckhoff
Publikováno v:
Toxicology and applied pharmacology. 125(1)
No embryotoxic or teratogenic effects, considered to be treatment related, were observed in rabbits after daily oral doses of 3 mg/kg of 13-cis-retinoic acid (13-cis-RA) from Day 8 to Day 11 of gestation. In contrast, treatment with 15 mg/kg/day sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17a673d7aaa1350c12dec59c3ffb4ec
https://pubmed.ncbi.nlm.nih.gov/8128493
https://pubmed.ncbi.nlm.nih.gov/8128493
Publikováno v:
Development. 36:639-652
The inhibitory effect of 5-bromodeoxyuridine (BudR)-an analog of thymidine-on embryonic mouse limb-buds was studied in vitro employing an organ-culture system. The effect was found to be dose-related and also depended on the developmental stage of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::670c51760312ef4ef391a331bd23c176
https://doi.org/10.1242/dev.36.3.639
https://doi.org/10.1242/dev.36.3.639
Autor:
Edward J. Lammer, Diane T. Chen, Richard M. Hoar, Narsingh D. Agnish, Paul J. Benke, John T. Braun, Cynthia J. Curry, Paul M. Fernhoff, Art W. Grix, Ira T. Lott, James M. Richard, Shyan C. Sun
Publikováno v:
New England Journal of Medicine. 313:837-841
Retinoic acid, an analogue of vitamin A, is known to be teratogenic in laboratory animals and has recently been implicated in a few clinical case reports. To study the human teratogenicity of this agent, we investigated 154 human pregnancies with fet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5344af911827d76a338a1c38f1f76e07
https://doi.org/10.1056/nejm198510033131401
https://doi.org/10.1056/nejm198510033131401
Publikováno v:
Development. 36:623-638
As maternally administered 5-bromodeoxyuridine (BudR) is very quickly degraded by the liver, a combination of whole embryo culture and organ culture techniques was adopted to expose postimplantation mouse embryos to the analog and to study the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17eceee05742d0813ca95f7662921f0c
https://doi.org/10.1242/dev.36.3.623
https://doi.org/10.1242/dev.36.3.623
Publikováno v:
Journal of the American Academy of Dermatology. 11(4 Pt 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66117a50bd372b4519d9b3e6e3390d3
https://pubmed.ncbi.nlm.nih.gov/6593332
https://pubmed.ncbi.nlm.nih.gov/6593332
Autor:
Narsingh D. Agnish, D. M. Kochhar
Publikováno v:
Developmental biology. 56(1)
Organ culture techniques were employed to study the developmental potential of embryonic mouse limbs. Isolated limb buds from 12- and 13-day embryos grew well and, after 6 days in culture, well-defined scapula, humerus, radio-ulna, and digits were ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8273d7f169028edcec1087c0cfbf85db
https://pubmed.ncbi.nlm.nih.gov/838130
https://pubmed.ncbi.nlm.nih.gov/838130