Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Narsimha, Bogaraju"'
Autor:
Jagadeesh Babu Thentu, Nageswararao Muddana, Renny Abraham, Raghava Choudary Palacharla, Srinivasa Rao Ravella, Ramkumar Subramanian, Venkat Reddy Mekala, Shinde Anil Karbhari, Narsimha Bogaraju, Abdul Rasheed Mohammed, Gopinadh Bhyrapuneni, Ramakrishna Nirogi, Venkat Jasti
Publikováno v:
Journal of Medicinal Chemistry. 63:2833-2853
A series of chemical optimizations guided by in vitro affinity at the α4β2 receptor in combination with selectivity against the α3β4 receptor, pharmacokinetic evaluation, and in vivo efficacy in a forced swim test resulted in identification of 3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ac0220a5003d1184e2ad4655e6b000
https://doi.org/10.1021/acs.jmedchem.9b00790
https://doi.org/10.1021/acs.jmedchem.9b00790
Autor:
Ramakrishna, Nirogi, Abdul Rasheed, Mohammed, Anil Karbhari, Shinde, Shankar Reddy, Gagginapally, Durga Malleshwari, Kancharla, Srinivasa Rao, Ravella, Narsimha, Bogaraju, Vanaja Reddy, Middekadi, Ramkumar, Subramanian, Raghava Choudary, Palacharla, Vijay, Benade, Nageswararao, Muddana, Renny, Abraham, Rajesh Babu, Medapati, Jagadeesh Babu, Thentu, Venkat Reddy, Mekala, Surendra, Petlu, Bujji Babu, Lingavarapu, Sivasekhar, Yarra, Narendra, Kagita, Vinod Kumar, Goyal, Santosh Kumar, Pandey, Venkat, Jasti
Publikováno v:
Journal of medicinal chemistry. 64(15)
A series of oxadiazole derivatives were synthesized and evaluated as 5-hydroxytryptamine-4 receptor (5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0658b7f6a1d5f4d39f7637a5b2805752
https://pubmed.ncbi.nlm.nih.gov/34251799
https://pubmed.ncbi.nlm.nih.gov/34251799
Autor:
Pooja Singh, Nageswararao Muddana, Ramakrishna Nirogi, Narsimha Bogaraju, Abdul Rasheed Mohammed, Srinivasa Rao Ravella, Raghava Choudary Palacharla, Ramkumar Subramanian, Shankar Reddy Gagginapally, Shinde Anil Karbhari, Vanaja Reddy Middekadi, Durga Malleshwari Kancharla, Pradeep Jayarajan, Vijay Benade, Sumit Raosaheb Birangal
Publikováno v:
Journal of Medicinal Chemistry. 61:4993-5008
Alzheimer’s disease (AD) is a neurodegenerative disorder that has a higher prevalence and incidence in people older than 60 years. The need for improved AD therapies is unmet as the current therapies are symptomatic with modest efficacy. Partial ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99c12a66cd15dcfd5d91660e6cac491a
https://doi.org/10.1021/acs.jmedchem.8b00457
https://doi.org/10.1021/acs.jmedchem.8b00457
Autor:
Ramakrishna Nirogi, Mohammed Abdul Rasheed, Ramkumar Subramanian, Jayaprakash Tadiparthi, Rajesh Kallepalli, Pooja Singh, Joylee Fernandes, Narsimha Bogaraju, Purnachander Are, Surendra Petlu, Sumanth Yathavakilla, Arun Babu Vuyyuru, Sthevaan Vincent, Venkat Reddy Mekala, Praveena Nissankararao Mary
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adbfa0ef07ef1e4cf3e35e77a3ddcf1d
https://doi.org/10.1016/j.jalz.2018.06.1819
https://doi.org/10.1016/j.jalz.2018.06.1819
Autor:
Ramakrishna Nirogi, Srinivasa Rao Ravella, Shankar Reddy Gagginapally, Abdul Rasheed Mohammed, Narsimha Bogaraju
Publikováno v:
Green Chemistry Letters and Reviews. 7:150-157
Synthetic routes for 5-amino-6-chlorochroman-8-carboxylic acid 1 a key intermediate for several potent 5-HT4 agonists have been explored. An efficient, high yielding, and a concise synthetic route has been established with significant modifications t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20911a2ca425448f22f26c8043b1a5a0
https://doi.org/10.1080/17518253.2014.904010
https://doi.org/10.1080/17518253.2014.904010
Autor:
Shankar Reddy Gagginapalli, Ramakrishna Nirogi, Narsimha Bogaraju, Raghava Chowdary Palacharla, Vinod Kumar Goyal, Nageswara Rao Muddana, Pradeep Jayarajan, Vijay Benade, Srinivasa Rao Ravella, Laxman Kota, Abdul Rasheed Mohammed, Gopinadh Bhyrapuneni, Anil Shinde, Ramkumar Subramanian
Publikováno v:
European journal of medicinal chemistry. 103
Alzheimer's disease (AD) is a neurodegenerative disease which has a higher prevalence and incidence in older people. The need for improved AD therapies is unmet. The 5-hydroxytryptamine4 receptor (5-HT4R) partial agonists may be of benefit for both t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b006bd0e7b886175b3f0e538a24552
https://pubmed.ncbi.nlm.nih.gov/26363507
https://pubmed.ncbi.nlm.nih.gov/26363507